Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Devora Cohen-Karni"'
Publikováno v:
Nature Reviews Bioengineering. 1:193-207
Autor:
Thaiesha A. Wright, Katarzyna Szcześniak, Boyle C. Cheng, Jacek Jenczyk, Xiangyu Zhang, Stefan Jurga, Saadyah Averick, Dominik Konkolewicz, Devora Cohen-Karni, Robert T. Mathers, Marina Kovaliov, Richard C. Page, Dong Meng
Publikováno v:
Bioconjugate Chemistry. 31:939-947
Due to their capacity to conduct complex organic transformations, enzymes find extensive use in medical and industrial settings. Unfortunately, enzymes are limited by their poor stability when exposed to harsh non-native conditions. While a host of m
Publikováno v:
Biophys Rev
The ability to manipulate the electrophysiology of electrically active cells and tissues has enabled a deeper understanding of healthy and diseased tissue states. This has primarily been achieved via input/output (I/O) bioelectronics that interface e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0d6508ba1d26f800f6babdba627a50
https://europepmc.org/articles/PMC8717360/
https://europepmc.org/articles/PMC8717360/
Autor:
Yingqiao Wang, Devora Cohen-Karni, Esther Bedoyan, Tzahi Cohen-Karni, Raghav Garg, Maysamreza Chamanzar, Anna Kalmykov, Jay W. Reddy, Sahil K. Rastogi
Objective. Three-dimensional (3D) neuronal spheroid culture serves as a powerful model system for the investigation of neurological disorders and drug discovery. The success of such a model system requires techniques that enable high-resolution funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c306f6d6974cfe1eecf218266c267ecf
https://doi.org/10.1101/2020.11.29.401638
https://doi.org/10.1101/2020.11.29.401638
Autor:
Devora Cohen-Karni, Saadyah Averick, Chen Xu, Kevin A. Burridge, Nestor D. Tomycz, Nicholas M. Daman, Marina Kovaliov, Dominik Konkolewicz, J. Kenneth Wickiser, Dorian Mambelli, Samantha Sloane, Richard C. Page, J. Jared Guth
Publikováno v:
European Polymer Journal. 107:15-24
Protein polymer hybrids play an increasingly important role in therapeutics and biocatalysis. Synthesis of these biohybrids can be achieved by either the grafting-from or grafting-to strategy and are generally thought to be interchangeable. Therefore
Autor:
Saadyah Averick, Devora Cohen-Karni, Shaohua Li, Nestor D. Tomycz, Stephen Jaffee, Marina Kovaliov
Publikováno v:
Bioconjugate Chemistry. 28:1251-1259
The targeted delivery of polymers to neurons is a challenging yet important goal for polymer based drug delivery. We prepared a fentanyl based atom transfer radical polymerization (ATRP) initiator to target the Mu opioid receptor (MOR) for neuronal t
Autor:
Antonina Simakova, Sangwoo Park, Zongyu Wang, Krzysztof Matyjaszewski, Devora Cohen-Karni, Sipei Li, Saadyah Averick, Liye Fu, Hee Sung Chung
Publikováno v:
Biomacromolecules. 18:475-482
The synthesis of a sulfoxide-based water-soluble polymer, poly(2-(methylsulfinyl)ethyl acrylate) (polyMSEA), a polymeric analogue of DMSO, by atom transfer radical polymerization (ATRP) is reported. Well-defined linear polymers were synthesized using
Autor:
Saadyah Averick, Devora Cohen-Karni, Nestor D. Tomycz, Marina Kovaliov, Boyle C. Cheng, Shaohua Li, Donald Whiting
Publikováno v:
RSC Advances. 7:20015-20019
The synthesis of novel fentanyl acrylate derivatives via bromo-fentanyl using Heck coupling is described. The synthesis is concise and represents an efficient and useful method for functionalizing fentanyl for medicinal chemistry investigations. The
Autor:
Scott Graner, Devora Cohen-Karni, Dominik Konkolewicz, Marina Kovaliov, Theresa Ramelot, Saadyah Averick
Publikováno v:
Polymer Chemistry. 8:3992-3998
Aqueous initiators for continuous activator regeneration atom transfer radical polymerization (ICAR ATRP) was applied to graft well defined acrylamide, N,N-dimethylacrylamide and N-vinylimidazole homo and block copolymers from a model protein initiat
Publikováno v:
Polymer. 99:59-62
Post-polymerization functionalization is a critical tool in preparing functional materials. The critical aspects of post-polymerization reactions are high yields, short reaction times, simple purification, near stoichiometric amounts of reactants, an