Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Devon Zimmerman"'
Autor:
Carlos Gonzalez, Scott Probst, Steve Goodman, Randy Schweickart, Zhuoer Lin, Devon Zimmerman, Kara Levine, Samantha Sbardella, Zhimei Du, Anne Mayer, David Shaw, Hana Sheikh, Arshan Nazempour, Robert Tarsa, Steven Wall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c58a1a1179e4a141f91419f4855f8d49
https://doi.org/10.46220/2021cgt007
https://doi.org/10.46220/2021cgt007
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 118(4)
Retroviral gene delivery is widely used in T cell therapies for hematological cancers. However, viral vectors are expensive to manufacture, integrate genes in semi-random patterns, and their transduction efficiency varies between patients. In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe94771069978d2e7b185dbfcc05728
https://pubmed.ncbi.nlm.nih.gov/33480049
https://pubmed.ncbi.nlm.nih.gov/33480049
Retroviral gene delivery is widely used in T cell therapies for hematological cancers. However, viral vectors are expensive to manufacture, they integrate genes in semi-random patterns, and their transduction efficiency is highly variable. In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54a5b410b2ce8391a4dadfd4f12cab52
https://doi.org/10.22541/au.160262388.84292192/v1
https://doi.org/10.22541/au.160262388.84292192/v1
Publikováno v:
Bioengineering & Translational Medicine. 2:212-221
While many blood substitutes are based on mammalian hemoglobins (e.g., human hemoglobin, HbA), the naturally extracellular hemoglobins of invertebrates (a.k.a. erythrocruorins, Ecs) are intriguing alternative oxygen carriers. Specifically, the erythr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c88ec583650265001e5ce24ec56ffcae
https://doi.org/10.1002/btm2.10067
https://doi.org/10.1002/btm2.10067
Autor:
Devon Zimmerman, Sagar Shelake, Bharathikumar Vellalore Maruthachalam, Maria Ozerova, Amos Tsai, Vishal Nashine
Publikováno v:
Cryobiology. 97:277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42b06a1868ad4ae46c7bd628c609ad23
https://doi.org/10.1016/j.cryobiol.2020.10.110
https://doi.org/10.1016/j.cryobiol.2020.10.110
Publikováno v:
Protein Expression and Purification. 125:74-82
Although donated blood is the preferred material for transfusion, its limited availability and stringent storage requirements have motivated the development of blood substitutes. The giant extracellular hemoglobin (aka erythrocruorin) of the earthwor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8dee7b49f96a814a3765ce1a319c81
https://doi.org/10.1016/j.pep.2015.09.006
https://doi.org/10.1016/j.pep.2015.09.006
If a transgene is effectively delivered to a cell, its expression may still be limited by epigenetic mechanisms that silence the transgene. Indeed, once the transgene reaches the nucleus, it may be bound by histone proteins and condensed into heteroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657214b8343c4c5c0bced4aeb97ad95a
Publikováno v:
Biotechnology progress. 34(6)
If a transgene is effectively delivered to a cell, its expression may still be limited by epigenetic mechanisms that silence the transgene. Indeed, once the transgene reaches the nucleus, it may be bound by histone proteins and condensed into heteroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752abebf97b0862432208482973b84c2
https://pubmed.ncbi.nlm.nih.gov/30294957
https://pubmed.ncbi.nlm.nih.gov/30294957
Autor:
Noelle Comolli, Matthew Nicholas, Matthew Tucker, Kyle Spivack, Osheiza Abdulmalik, Jacob Elmer, Devon Zimmerman
Since donated red blood cells must be constantly refrigerated, they are often unavailable in remote areas and battlefields. The goal of this study was to synthesize a highly stable blood substitute that does not require refrigeration. Specifically, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751300f1705a7bdfeae4edb5ea23dc12
Since donated red blood cells must be constantly refrigerated, they are not available in remote areas and battlefields. We have previously shown that the hemoglobin of the earthworm Lumbricus terrestris (LtEc) is an effective and safe substitute for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd358ce8396f7aec3a276523b83c6eb
https://europepmc.org/articles/PMC5911234/
https://europepmc.org/articles/PMC5911234/