Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Devon Placides"'
Autor:
Chao Ma, Jerry B. Hunt, Maj-Linda B. Selenica, Awa Sanneh, Leslie A. Sandusky-Beltran, Mallory Watler, Rana Daas, Andrii Kovalenko, Huimin Liang, Devon Placides, Chuanhai Cao, Xiaoyang Lin, Michael B. Orr, Bei Zhang, John C. Gensel, David J. Feola, Marcia N. Gordon, Dave Morgan, Paula C. Bickford, Daniel C. Lee
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Alzheimer’s disease (AD) includes several hallmarks comprised of amyloid-β (Aβ) deposition, tau neuropathology, inflammation, and memory impairment. Brain metabolism becomes uncoupled due to aging and other AD risk factors, which ultimately lead
Externí odkaz:
https://doaj.org/article/eb73ef7b7394472091f6f6e6c914d923
Autor:
Devon Placides, Kevin Nash, Marcia N. Gordon, Mallory D. Watler, Dave Morgan, Andrii Kovalenko, April L. Lussier, Edwin J. Weeber, Sarah N. Fontaine, Laura J. Blair, Jerry B. Hunt, Leslie A. Sandusky-Beltran, Chad A. Dickey, Daniel C. Lee, Jeremy D. Baker, April L. Darling, John Ivan T. Calahatian, Maj-Linda B. Selenica, Chao Ma, Mackenzie D. Martin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-24 (2019)
Background Tau stabilizes microtubules; however, in Alzheimer’s disease (AD) and tauopathies, tau becomes hyperphosphorylated, aggregates, and results in neuronal death. Our group recently uncovered a unique interaction between polyamine metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f7e770da9aa071b4410d08c755536a
http://link.springer.com/article/10.1186/s13195-019-0507-y
http://link.springer.com/article/10.1186/s13195-019-0507-y
Autor:
Maj-Linda B. Selenica, Kevin Ratnasamy, Chad A. Dickey, Margaret Fahnestock, Laura J. Blair, Kevin Nash, Daniel C. Lee, Devon Placides, Andrii Kovalenko, April L. Darling, Erin L. Abner, Huimin Liang, Camilla Michalski, Sarah N. Fontaine, John Ivan T. Calahatian, Leslie A. Sandusky-Beltran, Joshua J. Gamsby, Jeremy D. Baker, Jerry B. Hunt, Chao Ma
Publikováno v:
J Clin Invest
Tauopathies display a spectrum of phenotypes from cognitive to affective behavioral impairments; however, mechanisms promoting tau pathology and how tau elicits behavioral impairment remain unclear. We report a unique interaction between polyamine me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33b1bc68c081762982c122956567e7b
https://doi.org/10.1172/jci126299
https://doi.org/10.1172/jci126299
Autor:
Henry Gong, Sandra Zivkovic, Umesh K. Jinwal, Vinh B. Dinh, Dale Chaput, Devon Placides, Yumeng Zhang, Stanley M. Stevens, Eni Cvitkovic, Ernide Frederic, Vedad Delic, Tam-Anh Phan, Christian Reynes, Daniel C. Lee, Josean Cruz, Hamed Mirzaei, Jeddidiah W. D. Griffin, Patrick C. Bradshaw
Publikováno v:
NeuroMolecular Medicine. 19:322-344
Parkinson's disease (PD) is a neurodegenerative disorder characterized by alpha-synuclein accumulation and loss of dopaminergic neurons in the substantia nigra (SN) region of the brain. Increased levels of alpha-synuclein have been shown to result in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759c2fc241ddc0aa8dca61b534d1faf5
https://doi.org/10.1007/s12017-017-8448-8
https://doi.org/10.1007/s12017-017-8448-8
Autor:
Leslie A. Sandusky, Patrick Reid, Marcia N. Gordon, Kevin Nash, Peter Moran, Jerry B. Hunt, Maj-Linda B. Selenica, Rodrigo Uricia, Daniel C. Lee, Chad A. Dickey, Miloni Savlia, Kevin Ratnasamy, Dave Morgan, Yashobha Ranaweera, Firas Abuqalbeen, Nina Slouha, Clement G.Y. Yang, Santiago Rodriguez-Ospina, Devon Placides
Tau accumulation remains one of the closest correlates of neuronal loss in Alzheimer's disease. In addition, tau associates with several other neurodegenerative diseases, collectively known as tauopathies, in which clinical phenotypes manifest as cog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fe1b3fbc016619ddce45dd04bb4dcd
https://europepmc.org/articles/PMC6605229/
https://europepmc.org/articles/PMC6605229/
Autor:
Maj-Linda B. Selenica, Kevin Ratnasamy, Daniel C. Lee, Leslie A. Sandusky, Kevin Nash, Devon Placides, Jerry B. Hunt, Firas Abuqualbeen
Publikováno v:
Alzheimer's & Dementia. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33a4bcf3e06ca779dc58d8cfed7186f2
https://doi.org/10.1016/j.jalz.2015.06.914
https://doi.org/10.1016/j.jalz.2015.06.914
Autor:
Jerry B. Hunt, Marcia N. Gordon, Kevin Nash, Santiago Rodrigez-Ospina, Clement G.Y. Yang, Devon Placides, Miloni Savlia, Peter Moran, Daniel C. Lee, Maj-Linda B. Selenica, David G. Morgan
Publikováno v:
Alzheimer's & Dementia. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c82c539bc321977eb1e8a55878a11c9
https://doi.org/10.1016/j.jalz.2013.05.638
https://doi.org/10.1016/j.jalz.2013.05.638