Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Devon M. Headen"'
Autor:
Maria M. Coronel, Devon M. Headen, Michael D. Hunckler, Haval Shirwan, Jessica D. Weaver, Andrés J. García
Publikováno v:
Am J Transplant
Transplantation of hydrogel-encapsulated allogeneic islets has been explored to reduce or eliminate the need for chronic systemic immunosuppression by creating a physical barrier which prevents direct antigen presentation. Although successful in rode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840096ed7c6cc706ce010741b8eeab9f
https://europepmc.org/articles/PMC6487074/
https://europepmc.org/articles/PMC6487074/
Autor:
Maria M. Coronel, Devon M. Headen, Cherie L. Stabler, Andrés J. García, Michael D. Hunckler, Jessica D. Weaver
Publikováno v:
Biomaterials. 172
The use of immunoisolating macrodevices in islet transplantation confers the benefit of safety and translatability by containing transplanted cells within a single retrievable device. To date, there has been limited development and characterization o
Publikováno v:
Microsystems & Nanoengineering. 4
Cells can be microencapsulated in synthetic hydrogel microspheres (microgels) using droplet microfluidics, but microfluidic devices with a single droplet generating geometry have limited throughput, especially as microgel diameter decreases. Here we
Autor:
Devon M. Headen, Jahizreal Aquart, Andrés J. García, Lonnie D. Shea, Jessica D. Weaver, Haval Shirwan, Christopher T. Johnson
Publikováno v:
Science Advances
VEGF-delivering synthetic hydrogel improves islet survival and function in extrahepatic transplant sites over current clinical method.
Islet transplantation is a promising alternative therapy for insulin-dependent patients, with the potential to
Islet transplantation is a promising alternative therapy for insulin-dependent patients, with the potential to
Autor:
Andrés J. García, José M. Cervantes-Uc, Juan V. Cauich-Rodríguez, C. Mojica-Cardoso, Devon M. Headen, J. Santa-Olalla Tapia, L. H. Chan-Chan, R.F. Vargas-Coronado, J.L.A. Perales-Alcacio
Publikováno v:
Journal of Biomaterials Science, Polymer Edition. 24:1601-1617
Novel biodegradable segmented polyurethanes (SPUs) were synthesized with polycaprolactone diol, 4,4'-methylen bis (cyclohexyl isocyanate) (HMDI), and either L-glutathione or its constituent amino acids (L-glutamic acid, L-cysteine and glycine) as cha
Autor:
Cristina González-García, Devon M. Headen, Greg A. Foster, Manuel Salmerón-Sánchez, Andrés J. García, Haval Shirwan
Publikováno v:
Biomaterials. 113
Degradable hydrogels to deliver bioactive proteins represent an emerging platform for promoting tissue repair and vascularization in various applications. However, implanting these biomaterials requires invasive surgery, which is associated with comp
Autor:
Milton R. Brown, Andrés J. García, Michael Davis, Gigi Joseph, Allen L. Liu, Devon M. Headen, Anita Saraf, Daiana Weiss, W. R. Taylor
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Following myocardial injury, 1 in 3 patients will have irreversible cardiac damage and develop congestive heart failure. The paracrine factors secreted by mesenchymal stem cells (MSCs) have shown promise in regenerating damaged heart tissue through t
Publikováno v:
Biomedical Microdevices. 14:999-1007
Swimming microrobots are envisioned to impact minimally invasive diagnosis, localized treatment of diseases, and environmental monitoring. Dynamics of micro-scale swimming robots falls in the realm of low Reynolds number, where viscous forces exerted
Autor:
Michael D. Hunckler, Kyle B. Woodward, Pradeep Shrestha, Jessica D. Weaver, Min Tan, William S. Bowen, Esma S. Yolcu, Andrés J. García, Maria M. Coronel, Devon M. Headen, Haval Shirwan
Publikováno v:
Transplantation. 102:S291
Autor:
Haval Shirwan, Kyle B. Woodward, Devon M. Headen, Hong Zhao, Pradeep Shrestha, Min Tan, William S. Bowen, María M. Coronel, Michael D. Hunckler, Jessica D. Weaver, Esma S. Yolcu, Andrés J. García
Publikováno v:
The Journal of Immunology. 200:55.36-55.36
Allogenic islet transplantation is an effective therapy for type 1 diabetes in the clinic. Sustained graft survival requires chronic immunosuppression that has adverse effects. Islet graft rejection is initiated and perpetuated by T effector cells (T