Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Devon M Fitzgerald"'
Autor:
Devon M Fitzgerald
Publikováno v:
eLife, Vol 8 (2019)
The way that bacteria grow – either floating in liquid or attached to a surface – affects their ability to evolve antimicrobial resistance and our ability to treat infections.
Externí odkaz:
https://doaj.org/article/dcf6a091ddcf470cba06fc687d74831f
Autor:
Devon M Fitzgerald, Susan M Rosenberg
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1007995 (2019)
Mutations drive evolution and were assumed to occur by chance: constantly, gradually, roughly uniformly in genomes, and without regard to environmental inputs, but this view is being revised by discoveries of molecular mechanisms of mutation in bacte
Externí odkaz:
https://doaj.org/article/dbdb4898ff744634b84d6e0f41ffabba
Autor:
Jonatan Axelsson, Danielle LeBlanc, Habiballah Shojaeisaadi, Matthew J Meier, Devon M. Fitzgerald, Daniela Nachmanson, Jedidiah Carlson, Alexandra Golubeva, Jake Higgins, Thomas Smith, Fang Yin Lo, Richard Pilsner, Andrew Williams, Jesse Salk, Francesco Marchetti, Carole Yauk
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract De novo mutations (DNMs) are drivers of genetic disorders. However, the study of DNMs is hampered by technological limitations preventing accurate quantification of ultra-rare mutations. Duplex Sequencing (DS) theoretically has T. Blood MF a
Externí odkaz:
https://doaj.org/article/642eb87b6f244a7fb80c1b98bc0a8549
Autor:
Devon M Fitzgerald, Susan M Rosenberg
Publikováno v:
eLife, Vol 6 (2017)
Tumor-growth-factor-beta signaling helps cancer cells to evolve and become resistant to drugs by down-regulating accurate DNA repair.
Externí odkaz:
https://doaj.org/article/3f4e1fa70d6c4b6096b188da4430f449
Publikováno v:
PLoS Genetics, Vol 11, Iss 9, p e1005456 (2015)
Externí odkaz:
https://doaj.org/article/2d1c8eff0a5b4a86bcec3b4ecc715e5a
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004649 (2014)
Flagellar synthesis is a highly regulated process in all motile bacteria. In Escherichia coli and related species, the transcription factor FlhDC is the master regulator of a multi-tiered transcription network. FlhDC activates transcription of a numb
Externí odkaz:
https://doaj.org/article/860e074710684a4d92eb681c9d57c973
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24364 (2011)
The neural cell adhesion molecule L1 is critical for brain development and plays a role in learning and memory in the adult. Ethanol inhibits L1-mediated cell adhesion and neurite outgrowth in cerebellar granule neurons (CGNs), and these actions migh
Externí odkaz:
https://doaj.org/article/e145037883d24dbb830e8c006202da3c
Publikováno v:
bioRxiv
Genome-scale analyses have revealed many transcription factor binding sites within, rather than upstream of genes, raising questions as to the function of these binding sites. Here, we use complementary approaches to map the regulon of theEscherichia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3aca87bab5693ff25e513fc8ce4bd4a
https://europepmc.org/articles/PMC9934606/
https://europepmc.org/articles/PMC9934606/
Autor:
Elizabeth Schmidt, Devon M. Fitzgerald, Camila Zanette, Gavin D. Meredith, Mark A. McElwain, Raul Burciaga, Kevin C. Vavra, Thomas H. Smith, Jesse J. Salk, Jake Higgins
Publikováno v:
Cancer Research. 83:LB254-LB254
Sensitive and specific detection of low frequency mutations in acute myeloid leukemia (AML) is critical in research of minimal residual disease (MRD). At variant allele frequencies (VAF) below approximately 1%, PCR and sequencing errors result in pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8149c84dc67c0e88b96201842fabadde
https://doi.org/10.1158/1538-7445.am2023-lb254
https://doi.org/10.1158/1538-7445.am2023-lb254
Publikováno v:
Cells
Cells, Vol 10, Iss 2275, p 2275 (2021)
Cells, Vol 10, Iss 2275, p 2275 (2021)
The Escherichia coli SOS response to DNA damage, discovered and conceptualized by Evelyn Witkin and Miroslav Radman, is the prototypic DNA-damage stress response that upregulates proteins of DNA protection and repair, a radical idea when formulated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5fd827b808bdc9ff60d60b1d8388ab
https://pubmed.ncbi.nlm.nih.gov/34571923
https://pubmed.ncbi.nlm.nih.gov/34571923