Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Devon L Moose"'
Autor:
Melissa A. Marchal, Devon L. Moose, Afshin Varzavand, Nicole E. Jordan, Destiney Taylor, Munir R. Tanas, James A. Brown, Michael D. Henry, Christopher S. Stipp
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionAbl family kinases function as proto-oncogenes in various leukemias, and pro-tumor functions have been discovered for Abl kinases in many solid tumors as well. However, a growing body of evidence indicates that Abl kinases can function to
Externí odkaz:
https://doaj.org/article/3f74f3b22e7d4202910ff27fb642931d
Autor:
Courtney A. Kaemmer, Shaikamjad Umesalma, Chandra K. Maharjan, Devon L. Moose, Goutham Narla, Sarah L. Mott, Gideon K. D. Zamba, Patrick Breheny, Benjamin W. Darbro, Andrew M. Bellizzi, Michael D. Henry, Dawn E. Quelle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Pancreatic neuroendocrine neoplasms (pNENs) are slow growing cancers of increasing incidence that lack effective treatments once they become metastatic. Unfortunately, nearly half of pNEN patients present with metastatic liver tumors at diag
Externí odkaz:
https://doaj.org/article/ae2055035fc14c58a5dbf133596a14d9
Autor:
Devon L. Moose, Michael D. Henry
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 4 (2020)
During metastasis, cancer cells traverse the circulation to reach distant organs. Conventionally, this journey has been regarded as mechanically destructive to circulating tumor cells from solid tissues. We have recently shown that cancer cells from
Externí odkaz:
https://doaj.org/article/f99e319b7a3149868123ebd8bb48fe05
Autor:
Devon L. Moose, Benjamin L. Krog, Tae-Hyung Kim, Lei Zhao, Sophia Williams-Perez, Gretchen Burke, Lillian Rhodes, Marion Vanneste, Patrick Breheny, Mohammed Milhem, Christopher S. Stipp, Amy C. Rowat, Michael D. Henry
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3864-3874.e6 (2020)
Summary: During metastasis, cancer cells are exposed to potentially destructive hemodynamic forces including fluid shear stress (FSS) while en route to distant sites. However, prior work indicates that cancer cells are more resistant to brief pulses
Externí odkaz:
https://doaj.org/article/90d7b137bfca43899cdd2b65c1b3c7df
Autor:
Courtney Yong, Devon L Moose, Nadine Bannick, Wade R Gutierrez, Marion Vanneste, Robert Svensson, Patrick Breheny, James A Brown, Rebecca D Dodd, Michael B Cohen, Michael D Henry
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0232807 (2020)
Here we have improved an existing mouse model of prostate cancer based on prostate-specific deletion of Pten and Trp53 by incorporating a Cre-activatable luciferase reporter. By coupling the deletion of those genes to the activation of a luciferase r
Externí odkaz:
https://doaj.org/article/ce7d1f3ddce84cf390873022563396c7
Autor:
Han Chen, Sommer Y. Osman, Devon L. Moose, Marion Vanneste, Jared L. Anderson, Michael D. Henry, Robbyn K. Anand
Publikováno v:
Lab on a Chip.
Dielectrophoretic capture of circulating melanoma cell (CMC) and white blood cells (WBCs) is quantified as a function of electric field frequency, and the optimized conditions are utilized to isolate CMCs from patient-derived blood samples.
Autor:
Devon L. Moose, Amanda N. Pope, Marion Vanneste, Patrick Breheny, Eric B. Taylor, Michael D. Henry
Publikováno v:
Cancer Research. 83:B047-B047
Background and Purpose: Circulating tumor cells (CTCs) are exposed to mechanical and biochemical stresses including fluid shear stress (FSS), due to blood flow, and oxidative distress, from a lack of matrix attachment. Recently we have shown that via
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
The sodium leak channel NARROW ABDOMEN (NA)/ NALCN is an important component of circadian pacemaker neuronal output. In Drosophila, rhythmic expression of the NA channel regulator Nlf-1 in a subset of adult pacemaker neurons has been proposed to cont
Externí odkaz:
https://doaj.org/article/f456283e9fc045b7b679ba6715176c68
Autor:
Marisa R Buchakjian, Nicole M Merritt, Devon L Moose, Adam J Dupuy, Munir R Tanas, Michael D Henry
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183469 (2017)
Genetic mouse models of soft tissue sarcoma provide critical insights into disease pathophysiology, which are oftentimes unable to be extracted from human tumor samples or xenograft models. In this study we describe a mouse model of soft tissue sarco
Externí odkaz:
https://doaj.org/article/110cec91e0cb46afa5b7de457cbbbd2d
Publikováno v:
Journal of Visualized Experiments.
During metastasis, cancer cells from solid tissues, including epithelia, gain access to the lymphatic and hematogenous circulation where they are exposed to mechanical stress due to hemodynamic flow. One of these stresses that circulating tumor cells