Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Devin Wahl"'
Autor:
Devin Wahl, Sydney J. Risen, Shelby C. Osburn, Tobias Emge, Sadhana Sharma, Vincenzo S. Gilberto, Anushree Chatterjee, Prashant Nagpal, Julie A. Moreno, Thomas J. LaRocca
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Neuroinflammation contributes to impaired cognitive function in brain aging and neurodegenerative disorders like Alzheimer’s disease, which is characterized by the aggregation of pathological tau. One major driver of both age- and tau-asso
Externí odkaz:
https://doaj.org/article/5605af35a84d4c0f8db032124aca9f4d
Publikováno v:
Experimental Gerontology, Vol 192, Iss , Pp 112458- (2024)
Reducing neuroinflammation, a key contributor to brain aging and neurodegenerative diseases, is a promising strategy for improving cognitive function in these settings. The FDA-approved nucleoside reverse transcriptase inhibitor 3TC (Lamivudine) has
Externí odkaz:
https://doaj.org/article/791b80b31cb4467192ca2845385f25df
Autor:
Devin Wahl, Zachary S. Clayton
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/3d5ff8f441974efd919e39655115b601
Autor:
Michel Bernier, Dylan Harney, Yen Chin Koay, Antonio Diaz, Abhishek Singh, Devin Wahl, Tamara Pulpitel, Ahmed Ali, Vince Guiterrez, Sarah J. Mitchell, Eun-Young Kim, John Mach, Nathan L. Price, Miguel A. Aon, David G. LeCouteur, Victoria C. Cogger, Carlos Fernandez-Hernando, John O’Sullivan, Mark Larance, Ana Maria Cuervo, Rafael de Cabo
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 6, Iss 1, Pp 1-11 (2020)
Abstract There is an unmet need and urgency to find safe and effective anti-obesity interventions. Our recent study in mice fed on obesogenic diet found that treatment with the alcohol aversive drug disulfiram reduced feeding efficiency and led to a
Externí odkaz:
https://doaj.org/article/6764f6e5a0bd403f9dbc67a86fdcd3e6
Autor:
Margalida Torrens-Mas, Cayetano Navas-Enamorado, Devin Wahl, Andres Sanchez-Polo, Anna Picca, Jordi Oliver, Pilar Roca, Marta Gonzalez-Freire
Publikováno v:
Nutrients, Vol 14, Iss 21, p 4535 (2022)
Calorie restriction (CR), defined as a reduction of the total calorie intake of 30% to 60% without malnutrition, is the only nutritional strategy that has been shown to extend lifespan, prevent or delay the onset of age-associated diseases, and delay
Externí odkaz:
https://doaj.org/article/c92ec2c5a99841e48a2be72b38b31e1c
Autor:
Devin Wahl, Thomas J. LaRocca
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
Aging is the greatest risk factor most diseases, including cardiovascular disorders, cancers, diabetes, and neurodegeneration, but select nutritional interventions may profoundly reduce the risk for these conditions. These interventions include calor
Externí odkaz:
https://doaj.org/article/10ecc948bb8d4a5c9038dd23ddcfaa2e
Autor:
Devin Wahl, Samantha M. Solon-Biet, Victoria C. Cogger, Luigi Fontana, Stephen J. Simpson, David G. Le Couteur, Rosilene V. Ribeiro
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104481- (2019)
Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders, and neurodegenerative disease. There is emerging evidence that interventions that improve metabolic health with aging may also be effective for brain heal
Externí odkaz:
https://doaj.org/article/6bf0f2e42e554968bf2b530decc0a09b
Autor:
Devin Wahl, Samantha M. Solon-Biet, Qiao-Ping Wang, Jibran A. Wali, Tamara Pulpitel, Ximonie Clark, David Raubenheimer, Alistair M. Senior, David A. Sinclair, Gregory J. Cooney, Rafael de Cabo, Victoria C. Cogger, Stephen J. Simpson, David G. Le Couteur
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2234-2243.e6 (2018)
Summary: Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-protein, high-carbohydrate (LPHC) diets also extend lifespan, but it is not known whether they are beneficial for brain health. We compared hippoca
Externí odkaz:
https://doaj.org/article/01bfc1c1dff647aeb3faeae44f8706aa
Autor:
Devin Wahl, Meghan E. Smith, Cali M. McEntee, Alyssa N. Cavalier, Shelby C. Osburn, Samuel D. Burke, Randy A. Grant, David Nerguizian, Daniel S. Lark, Christopher D. Link, Thomas J. LaRocca
Publikováno v:
Aging Cell. 22