Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Devin R Polichuk"'
Autor:
Kirsten R. Benjamin, D. Dengrove, T. Treynor, Hanxiao Jiang, Darwin W. Reed, Karl Fisher, Douglas J. Pitera, S. Secrest, Kenneth W. Ellens, Patrick J. Westfall, M. Yu, Rika Regentin, T. Iqbal, A. Main, H. Tsuruta, Derek McPhee, Tizita Horning, R. Vazquez, S. Bajad, Ronald Henry, G. Dang, Keat H. Teoh, Jefferson C. Lievense, J. Galazzo, Scott Fickes, L. Kizer, Don Diola, Anna Tai, K. K. Reiling, B. Lieu, Patrick S. Covello, Lars F. Westblade, G. Dorin, Sara P. Gaucher, M. Fleck, Jacob R. Lenihan, M. Hepp, Michael D. Leavell, N. S. Renninger, Lishan Zhao, D. Melis, Diana Eng, Lan Xu, Jay D. Keasling, Christopher J. Paddon, Nathan A. Moss, T. Geistlinger, Jack D. Newman, Devin R Polichuk, Yansheng Zhang
Publikováno v:
Nature. 496:528-532
Saccharomyces cerevisiae is engineered to produce high concentrations of artemisinic acid, a precursor of the artemisinin used in combination therapies for malaria treatment; an efficient and practical chemical process to convert artemisinic acid to
Publikováno v:
Phytochemistry. 71:1264-1269
The major components of the isoprenoid-rich essential oil of Artemisia annua L. accumulate in the subcuticular sac of glandular secretory trichomes. As part of an effort to understand isoprenoid biosynthesis in A. annua, an expressed sequence tags (E
Publikováno v:
Botany. 87:635-642
Limitations in the supply of the antimalarial compound artemisinin from Artemisia annua L. have led to an interest in understanding its biosynthesis and enhancing its production. Recent biochemical and molecular genetic data have implicated dihydroar
Publikováno v:
Phytochemistry. 68:1864-1871
Artemisinin, a sesquiterpene lactone endoperoxide derived from the glandular secretory trichomes (GSTs) of Artemisia annua, provides the basis for the most effective treatments of malaria. The biology and biochemistry of GSTs of the Asteraceae and th
Publikováno v:
FEBS Letters. 580:1411-1416
Artemisinin, a sesquiterpene lactone endoperoxide derived from the plant Artemisia annua, forms the basis of the most important treatments of malaria in use today. In an effort to elucidate the biosynthesis of artemisinin, an expressed sequence tag a
Autor:
Patrick S. Covello, Stephen J. Ambrose, and Andrew R. S. Ross, Peter H. Buist, Darwin W. Reed, Robert J. Sasata, Christopher K. Savile, Devin R. Polichuk
Publikováno v:
Journal of the American Chemical Society. 125:10635-10640
The mechanism by which the fatty acid acetylenase of Crepis alpina catalyzes crepenynic acid ((9Z)-octadeca-9-en-12-ynoic acid) production from linoleic acid has been probed through the use of kinetic isotope effect (KIE) measurements. This was accom