Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Devin M Boe"'
Autor:
Beata Malachowska, Weng-Lang Yang, Andrea Qualman, Israel Muro, Devin M. Boe, Jed N. Lampe, Elizabeth J. Kovacs, Juan-Pablo Idrovo
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Burn induces a systemic response affecting multiple organs, including the liver. Since the liver plays a critical role in metabolic, inflammatory, and immune events, a patient with impaired liver often exhibits poor outcomes. The mortality r
Externí odkaz:
https://doaj.org/article/3902d53e7c5e4be794ef1dc208f20f0f
Autor:
Holly J. Hulsebus, Kevin M. Najarro, Rachel H. McMahan, Devin M. Boe, David J. Orlicky, Elizabeth J. Kovacs
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Alcohol consumption is commonplace in the United States and its prevalence has increased in recent years. Excessive alcohol use is linked to an increased risk of infections including pneumococcal pneumonia, mostly commonly caused by Streptococcus pne
Externí odkaz:
https://doaj.org/article/6a8e2a046e5c4b829ea003375bb76d09
Autor:
Devin M Boe, Holly J Hulsebus, Kevin M Najarro, Juliet E Mullen, Hyunmin Kim, Aik Choon Tan, Rachel H McMahan, Elizabeth J Kovacs
Publikováno v:
Journal of Leukocyte Biology. 112:1371-1386
Alveolar macrophages (AMs) are tissue-resident cells of the lower airways that perform many homeostatic functions critical for pulmonary health and protection against pathogens. However, little is known about the factors that shape AMs during healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fd3a08fa018731f1696592edf289a6e
https://doi.org/10.1002/jlb.3hi0620-399rr
https://doi.org/10.1002/jlb.3hi0620-399rr
Publikováno v:
Advances in geriatric medicine and research. 4(2)
Advanced age escalates post-burn complications and older burn patients, and even those with relatively minor burns, have worse clinical outcomes after injury. While the mechanism(s) responsible for the compounding effects of age and burn injury have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c6844dbf8de94016c63665b1151f1f2
https://pubmed.ncbi.nlm.nih.gov/35913894
https://pubmed.ncbi.nlm.nih.gov/35913894
Autor:
Holly J. Hulsebus, Juan Pablo Idrovo, Rebecca L. McCullough, Rachel H. McMahan, Kiran U Dyamenahalli, Elizabeth J. Kovacs, Devin M. Boe, Travis Walrath
Publikováno v:
J Leukoc Biol
The gastrointestinal (GI) tract is a vitally important site for the adsorption of nutrients as well as the education of immune cells. Homeostasis of the gut is maintained by the interplay of the intestinal epithelium, immune cells, luminal Ags, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fc6c291be148f67b6b6423c9585fb4
https://doi.org/10.1002/jlb.3ri0620-405rr
https://doi.org/10.1002/jlb.3ri0620-405rr
Publikováno v:
J Trauma Acute Care Surg
BACKGROUND Burn injury still has a high attributable mortality. The elevated mortality rate of severe burns is still concerning. Hepatic inflammation and injury are common after burns and are associated with poor outcomes. Necroptosis is a programmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33b2d06f8d12bc6015fe9769d443ae5
https://doi.org/10.1097/ta.0000000000002865
https://doi.org/10.1097/ta.0000000000002865
Autor:
Travis Walrath, Elizabeth J. Kovacs, Juan Pablo Idrovo, Rachel H. McMahan, Devin M. Boe, Soncy Kaahui
Publikováno v:
J Trauma Acute Care Surg
BACKGROUND: Elderly burn patients exhibit a lower survival rate compared with younger counterparts. The liver is susceptible to damage after burn injury, which predisposes to poor outcomes. Lipid homeostasis and the antioxidant glutathione system pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5e2fa616dfcb1b4374eb1ac32c60ab
https://pubmed.ncbi.nlm.nih.gov/33306599
https://pubmed.ncbi.nlm.nih.gov/33306599
Autor:
Kevin M, Najarro, Devin M, Boe, Travis M, Walrath, Juliet E, Mullen, Madison T, Paul, John H, Frankel, Holly J, Hulsebus, Juan-Pablo, Idrovo, Rachel H, McMahan, Elizabeth J, Kovacs
Publikováno v:
Exp Gerontol
BACKGROUND: Advanced age is an independent risk factor for morbidity and mortality after burn injury. Following burn, the intestines can become permeable leading to the leakage of bacteria and their products from the lumen of the ileum to the portal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089f7e047b049b4432ddf59e9fdb3d0f
https://doi.org/10.1016/j.exger.2021.111654
https://doi.org/10.1016/j.exger.2021.111654
Publikováno v:
Clinics in Geriatric Medicine. 33:459-471
With the coming of the “Silver Tsunami,” expanding our knowledge about how a variety of intrinsic and extrinsic factors affect the immune system in the elderly is both timely and of immediate clinical need. It is clear that the global population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72037ae1f6816ebc3848280f27fa6591
https://doi.org/10.1016/j.cger.2017.06.002
https://doi.org/10.1016/j.cger.2017.06.002
Publikováno v:
Clinical and Experimental Immunology. 187:16-25
Summary The world is undergoing an unprecedented shift in demographics, with the number of individuals over the age of 60 years projected to reach 2 billion or more by 2050, representing 22% of the global population. Elderly people are at a higher ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98cb929a53ae071132f4cfccd02c7d78
https://doi.org/10.1111/cei.12881
https://doi.org/10.1111/cei.12881