Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Devin Leake"'
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167088 (2016)
The fields of antibody engineering, enzyme optimization and pathway construction rely increasingly on screening complex variant DNA libraries. These highly diverse libraries allow researchers to sample a maximized sequence space; and therefore, more
Externí odkaz:
https://doaj.org/article/10a74fc5092240caa0aa18a504632fd0
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156478 (2016)
Many applications in molecular biology can benefit from improved PCR amplification of DNA segments containing a wide range of GC content. Conventional PCR amplification of DNA sequences with regions of GC less than 30%, or higher than 70%, is complex
Externí odkaz:
https://doaj.org/article/f89a17184384437c8776cb90a9227913
Autor:
Robyn P Hickerson, Winston C Wey, David L Rimm, Tycho Speaker, Susie Suh, Manuel A Flores, Emilio Gonzalez-Gonzalez, Devin Leake, Christopher H Contag, Roger L Kaspar
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Despite the development of potent siRNAs that effectively target genes responsible for skin disorders, translation to the clinic has been hampered by inefficient delivery through the stratum corneum barrier and into the live cells of the epidermis. A
Externí odkaz:
https://doaj.org/article/5b246f274dc140719661a9ecf71eb076
Autor:
Žaklina Strezoska, Abel Licon, Josh Haimes, Katie Jansen Spayd, Kruti M Patel, Kevin Sullivan, Katarzyna Jastrzebski, Kaylene J Simpson, Devin Leake, Anja van Brabant Smith, Annaleen Vermeulen
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42341 (2012)
RNAi screening using pooled shRNA libraries is a valuable tool for identifying genetic regulators of biological processes. However, for a successful pooled shRNA screen, it is imperative to thoroughly optimize experimental conditions to obtain reprod
Externí odkaz:
https://doaj.org/article/eb94d0add74e441f93937a750fe12195
Autor:
Angela Schoolmeesters, Teresa Eklund, Devin Leake, Annaleen Vermeulen, Queta Smith, Shelley Force Aldred, Yuriy Fedorov
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5605 (2009)
BACKGROUND:Mesenchymal stem (MS) cells are excellent candidates for cell-based therapeutic strategies to regenerate injured tissue. Although human MS cells can be isolated from bone marrow and directed to differentiate by means of an osteogenic pathw
Externí odkaz:
https://doaj.org/article/b9d31ec996a549c887f1acd3e264fa91
Autor:
John A. Martignetti, Goutham Narla, Devin Leake, Esteban A. Terzo, Jaya Sangodkar, Fei Huang, Analisa DiFeo
Supplementary Figure 7 from KLF6-SV1 Is a Novel Antiapoptotic Protein That Targets the BH3-Only Protein NOXA for Degradation and Whose Inhibition Extends Survival in an Ovarian Cancer Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0375e0e372e0fadd78e976f3dda668af
https://doi.org/10.1158/0008-5472.22377729
https://doi.org/10.1158/0008-5472.22377729
Autor:
John A. Martignetti, Goutham Narla, Devin Leake, Esteban A. Terzo, Jaya Sangodkar, Fei Huang, Analisa DiFeo
Supplementary Figure 1 from KLF6-SV1 Is a Novel Antiapoptotic Protein That Targets the BH3-Only Protein NOXA for Degradation and Whose Inhibition Extends Survival in an Ovarian Cancer Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adfc0b641eebfb34e806193134f4750b
https://doi.org/10.1158/0008-5472.22377750
https://doi.org/10.1158/0008-5472.22377750
Autor:
John A. Martignetti, Goutham Narla, Devin Leake, Esteban A. Terzo, Jaya Sangodkar, Fei Huang, Analisa DiFeo
Supplementary Figure 2 from KLF6-SV1 Is a Novel Antiapoptotic Protein That Targets the BH3-Only Protein NOXA for Degradation and Whose Inhibition Extends Survival in an Ovarian Cancer Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e753032f2e25b16453cb7b1d05ba4b6
https://doi.org/10.1158/0008-5472.22377747.v1
https://doi.org/10.1158/0008-5472.22377747.v1
Autor:
John A. Martignetti, Goutham Narla, Devin Leake, Esteban A. Terzo, Jaya Sangodkar, Fei Huang, Analisa DiFeo
Supplementary Figure 6 from KLF6-SV1 Is a Novel Antiapoptotic Protein That Targets the BH3-Only Protein NOXA for Degradation and Whose Inhibition Extends Survival in an Ovarian Cancer Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ddad31146e5bf7737b3d9069eecf6ab
https://doi.org/10.1158/0008-5472.22377732.v1
https://doi.org/10.1158/0008-5472.22377732.v1
Autor:
John A. Martignetti, Goutham Narla, Devin Leake, Esteban A. Terzo, Jaya Sangodkar, Fei Huang, Analisa DiFeo
Supplementary Figure 4 from KLF6-SV1 Is a Novel Antiapoptotic Protein That Targets the BH3-Only Protein NOXA for Degradation and Whose Inhibition Extends Survival in an Ovarian Cancer Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711ae6588803108175addc37855eb29b
https://doi.org/10.1158/0008-5472.22377741.v1
https://doi.org/10.1158/0008-5472.22377741.v1