Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Devin K Schweppe"'
Autor:
Patrick J Nygren, Sohum Mehta, Devin K Schweppe, Lorene K Langeberg, Jennifer L Whiting, Chad R Weisbrod, James E Bruce, Jin Zhang, David Veesler, John D Scott
Publikováno v:
eLife, Vol 6 (2017)
Scaffolding the calcium/calmodulin-dependent phosphatase 2B (PP2B, calcineurin) focuses and insulates termination of local second messenger responses. Conformational flexibility in regions of intrinsic disorder within A-kinase anchoring protein 79 (A
Externí odkaz:
https://doaj.org/article/5f4da514208a4f9884397e3ab2fb4cf5
Autor:
Timothy M. Locke, Rose Fields, Hayden Gizinski, George M. Otto, Melissa J.S. MacEwen, Domnita-Valeria Rusnac, Peixian He, David M. Shechner, Chris D. McGann, Matthew D. Berg, Judit Villen, Yasemin Sancak, Devin K. Schweppe
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114879- (2024)
Summary: Calcium ions play important roles in nearly every biological process, yet whole-proteome analysis of calcium effectors has been hindered by a lack of high-throughput, unbiased, and quantitative methods to identify protein-calcium engagement.
Externí odkaz:
https://doaj.org/article/83058aefa024485bafa97ed7f25ab95d
Autor:
Juan D Chavez, Jimmy K Eng, Devin K Schweppe, Michelle Cilia, Keith Rivera, Xuefei Zhong, Xia Wu, Terrence Allen, Moshe Khurgel, Akhilesh Kumar, Athanasios Lampropoulos, Mårten Larsson, Shuvadeep Maity, Yaroslav Morozov, Wimal Pathmasiri, Mathew Perez-Neut, Coriness Pineyro-Ruiz, Elizabeth Polina, Stephanie Post, Mark Rider, Dorota Tokmina-Roszyk, Katherine Tyson, Debora Vieira Parrine Sant'Ana, James E Bruce
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167547 (2016)
Chemical cross-linking mass spectrometry (XL-MS) provides protein structural information by identifying covalently linked proximal amino acid residues on protein surfaces. The information gained by this technique is complementary to other structural
Externí odkaz:
https://doaj.org/article/3ba39bd136884daab38534c011a3f079
Autor:
Qing Yu, Xinyue Liu, Mark P. Keller, Jose Navarrete-Perea, Tian Zhang, Sipei Fu, Laura P. Vaites, Steven R. Shuken, Ernst Schmid, Gregory R. Keele, Jiaming Li, Edward L. Huttlin, Edrees H. Rashan, Judith Simcox, Gary A. Churchill, Devin K. Schweppe, Alan D. Attie, Joao A. Paulo, Steven P. Gygi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Targeted proteomics enables robust hypothesis-driven research. Here, Yu et al. present a multiplexed approach for targeted pathway proteomics and apply it to quantify protein families across 480 fully genotyped Diversity Outbred mice, revealing impac
Externí odkaz:
https://doaj.org/article/cd1a101b49ee4dfbb34edecc65790389
Autor:
Gregory R. Keele, Ji-Gang Zhang, John Szpyt, Ron Korstanje, Steven P. Gygi, Gary A. Churchill, Devin K. Schweppe
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112715- (2023)
Summary: Maintenance of protein homeostasis degrades with age, contributing to aging-related decline and disease. Previous studies have primarily surveyed transcriptional aging changes. To define the effects of age directly at the protein level, we p
Externí odkaz:
https://doaj.org/article/0ebf66b87b984c858446f29df12b141a
Autor:
Jonathon J. O’Brien, Meagan Gadzuk-Shea, Phillip M. Seitzer, Ramin Rad, Fiona E. McAllister, Devin K. Schweppe
Publikováno v:
Journal of Proteome Research. 22:334-342
Stochastic, intensity-based precursor isolation can result in isotopically enriched fragment ions. This problem is exacerbated for large peptides and stable isotope labeling experiments using deuterium or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa069a3ac2ba38b2e6278ba46524915
https://doi.org/10.1021/acs.jproteome.2c00247
https://doi.org/10.1021/acs.jproteome.2c00247
Publikováno v:
Cell Chemical Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39da0800d4c3bdc0ad5fa5c8de195951
https://doi.org/10.1016/j.chembiol.2023.04.004
https://doi.org/10.1016/j.chembiol.2023.04.004
Autor:
Chris D. McGann, Will Barshop, Jesse Canterbury, Chuwei Lin, Wassim Gabriel, Mathias Wilhelm, Graeme McAlister, Devin K. Schweppe
Sample multiplexed quantitative proteomics has proved to be a highly versatile means to assay molecular phenotypes. Yet, stochastic precursor selection and precursor co-isolation can dramatically reduce the efficiency of data acquisition and quantita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08b407253ef33c35096c0bea42fe162b
https://doi.org/10.1101/2023.02.08.527705
https://doi.org/10.1101/2023.02.08.527705
Autor:
Ashley F. Tsue, Evan E. Kania, Diana Q. Lei, Rose Fields, Christopher D. McGann, Elliot Hershberg, Xinxian Deng, Maryanne Kihiu, Shao-En Ong, Christine M. Disteche, Sita Kugel, Brian J. Beliveau, Devin K. Schweppe, David M. Shechner
Publikováno v:
bioRxiv
Throughout biology, RNA molecules form complex networks of molecular interactions that are central to their function, but remain challenging to investigate. Here, we introduce Oligonucleotide-mediated proximity-interactome MAPping (O-MAP), a straight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6883d23e364b652de865445cd891798e
https://europepmc.org/articles/PMC9882335/
https://europepmc.org/articles/PMC9882335/
Autor:
Dylan C. Mitchell, Miljan Kuljanin, Jiaming Li, Jonathan G. Van Vranken, Nathan Bulloch, Devin K. Schweppe, Edward L. Huttlin, Steven P. Gygi
Publikováno v:
Nature Biotechnology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a210bf23be62c5c54982c849745fab1
https://doi.org/10.1038/s41587-022-01539-0
https://doi.org/10.1038/s41587-022-01539-0