Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Devin Hasanally"'
Autor:
Rakesh Chaudhary, Devin Hasanally, Aleksandra Stamenkovic, Amir Ravandi, Grant N. Pierce, Riya Ganguly, Thane G. Maddaford
Publikováno v:
Molecular and Cellular Biochemistry. 437:163-175
The omega-3 fatty acid, alpha linolenic acid (ALA) found in plant-derived foods induces significant cardiovascular benefits when ingested. ALA may be cardioprotective during ischemia; however, the mechanism(s) responsible for this effect is unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31519ab7171e0bcdd5a7cdfeaad76c37
https://doi.org/10.1007/s11010-017-3104-z
https://doi.org/10.1007/s11010-017-3104-z
Autor:
Devin Hasanally, Christopher W. White, Ganghong Tian, Ryan Lillico, Stephen R. Large, Jayan Nagendran, Ian M.C. Dixon, Larry V. Hryshko, E. Ambrose, Darren H. Freed, Keith J. Simons, T.W. Lee, Fei Wang, Bo Xiang, Ayyaz Ali, A. Müller, Ted M. Lakowski, Rakesh C. Arora, Simon Messer, Y. Li, Ousama Rachid, H. Le, Jaskiran Sandha
Publikováno v:
American Journal of Transplantation. 16:783-793
Hearts donated following circulatory death (DCD) may represent an additional source of organs for transplantation; however, the impact of donor extubation on the DCD heart has not been well characterized. We sought to describe the physiologic changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb126249bbea5672350c5adad0cddd4f
https://doi.org/10.1111/ajt.13543
https://doi.org/10.1111/ajt.13543
Autor:
David Chan, Lorrie A. Kirshenbaum, Xuchu Que, Grant N. Pierce, Sotirios Tsimikas, Devin Hasanally, Ming Yow Hung, Yusu Gu, William H. Bradford, Aleksandra Stamenkovic, Amir Ravandi, Masahiko Hoshijima, Andrea L. Edel, Victoria Margulets, Davinder S. Jassal, David Cheung, Nancy D. Dalton, Phuong Miu, Joseph L. Witztum, Rakesh Chaudhary, Calvin Yeang, Kirk L. Peterson
Aims Myocardial ischaemia followed by reperfusion (IR) causes an oxidative burst resulting in cellular dysfunction. Little is known about the impact of oxidative stress on cardiomyocyte lipids and their role in cardiac cell death. Our goal was to ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb80245a4a8a1418279fc7b38262332
https://europepmc.org/articles/PMC6302283/
https://europepmc.org/articles/PMC6302283/
Autor:
Davinder S. Jassal, Devin Hasanally, Rakesh Chaudhary, Amir Ravandi, Piotr Wtorek, James A. Thliveris, Megan daSilva, Jordyn Lerner, Anita K. Sharma, Matthew R. Zeglinski, Pawan K. Singal, Sheena Premecz
Publikováno v:
Canadian Journal of Cardiology. 30:359-367
Doxorubicin (DOX) and trastuzumab (TRZ) are highly effective chemotherapeutic agents in the breast cancer setting, limited by their cardiotoxic side effects. Among the potential mechanisms for this drug-induced cardiomyopathy, increased production of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ab13a957bf558df317a04f275d0ba3
https://doi.org/10.1016/j.cjca.2013.11.013
https://doi.org/10.1016/j.cjca.2013.11.013
Autor:
P. Mundt, Devin Hasanally, Yun Li, Ayyaz Ali, Stephen R. Large, Larry V. Hryshko, Christopher W. White, Darren H. Freed, S. Colah, Bo Xiang, Julianne Klein, Matthew Lytwyn, Amir Ravandi, T.W. Lee, Rakesh C. Arora, Ganghong Tian
Publikováno v:
The Journal of Heart and Lung Transplantation. 32:734-743
Background Ex vivo heart perfusion (EVHP) has been proposed as a means to facilitate the resuscitation of donor hearts after cardiocirculatory death (DCD) and increase the donor pool. However, the current approach to clinical EVHP may exacerbate myoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e70865eb3a74458dd08a0e0c0316fb
https://doi.org/10.1016/j.healun.2013.04.016
https://doi.org/10.1016/j.healun.2013.04.016
Publikováno v:
Clinical Lipidology. 8:205-215
Long thought of as a bystander in pathophysiological processes, lipid molecules have emerged as bioactive mediators of cardiovascular pathology. There has been accumulating evidence from both in vivo and in vitro studies that demonstrate an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df28afba3b57593213912d217a666341
https://doi.org/10.2217/clp.13.13
https://doi.org/10.2217/clp.13.13
Publikováno v:
Lipids. 52(1)
Oxidized low-density lipoprotein (OxLDL) plays an important role in initiation and progression of atherosclerosis. Proatherogenic effects of OxLDL have been attributed to bioactive phospholipids generated during LDL oxidation. It is unknown what effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd06e1a266808db0d77a196e22146b48
https://pubmed.ncbi.nlm.nih.gov/27914034
https://pubmed.ncbi.nlm.nih.gov/27914034
Publikováno v:
Circulation. 132
Introduction: Despite restoration of blood flow to myocardium after ischemia, a large percentage of myocardial cells die after reperfusion. This phenomenon is termed ischemia/reperfusion injury (I/R). Oxidized phosphatidylcholines (OxPC) are generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e7648bb3f3e2f9275d995c9210dfb8e
https://doi.org/10.1161/circ.132.suppl_3.16872
https://doi.org/10.1161/circ.132.suppl_3.16872
Autor:
Christopher W. White, Julianne Klein, Stephen R. Large, P. Mundt, Amir Ravandi, Devin Hasanally, E. Ambrose, Darren H. Freed, Bo Xiang, Yun Li, Alison L. Müller, Rakesh C. Arora, T.W. Lee, Ganghong Tian, Larry V. Hryshko
Publikováno v:
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 34(1)
Ex vivo heart perfusion (EVHP) provides the opportunity to resuscitate unused donor organs and facilitates assessments of myocardial function that are required to demonstrate organ viability before transplantation. We sought to evaluate the effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15bb1e87a916bf17526a949f90dcc677
https://pubmed.ncbi.nlm.nih.gov/35760461
https://pubmed.ncbi.nlm.nih.gov/35760461
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Reperfusion of ischemic heart tissue leads to a rapid burst of reactive oxygen species which initiates a cascade of events that cumulate in cell death. The most susceptible biomolecules to oxidative injury are membrane associated phospholipids. Oxidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01cb88aa0b144a943e4be6419e8d3784
https://doi.org/10.1161/atvb.34.suppl_1.545
https://doi.org/10.1161/atvb.34.suppl_1.545