Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Devin A. Bradburn"'
Publikováno v:
Biol Chem
DHX36 is a eukaryotic DEAH/RHA family helicase that disrupts G-quadruplex structures (G4s) with high specificity, contributing to regulatory roles of G4s. Here we used a DHX36 truncation to examine the roles of the 13-amino acid DHX36-specific motif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925792222a614c5b2d7ccbb21acc258b
https://doi.org/10.1515/hsz-2020-0302
https://doi.org/10.1515/hsz-2020-0302
Autor:
Anne-Claude Gingras, Cecilia Blikstad, Katharine S. Ullman, Jagoree Roy, Vikash K Yadav, Izabella Krystkowiak, Malika Amyn Kaderali, Jennifer T. Wang, Douglas R. Mackay, Ylva Ivarsson, Devin A. Bradburn, Eirini Tsekitsidou, Callie P. Wigington, Cassandra J. Wong, Tim Stearns, Su Hyun Hong, Nikhil P Damle, Martha S. Cyert, Eduard Resch, Shou-Ling Xu, Norman E. Davey
Publikováno v:
Mol Cell
SummaryShort linear motifs (SLiMs) drive dynamic protein-protein interactions essential for signaling, but sequence degeneracy and low binding affinities make them difficult to identify. We harnessed unbiased systematic approaches for SLiM discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b884773d32528587d0f9d3cfe127763
https://publica.fraunhofer.de/handle/publica/264773
https://publica.fraunhofer.de/handle/publica/264773
Publikováno v:
The Journal of biological chemistry. 293(6)
Single-stranded DNA (ssDNA) and RNA regions that include at least four closely spaced runs of three or more consecutive guanosines strongly tend to fold into stable G-quadruplexes (G4s). G4s play key roles as DNA regulatory sites and as kinetic traps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3beac9e68d50842a098185ade7a57352
https://pubmed.ncbi.nlm.nih.gov/29269411
https://pubmed.ncbi.nlm.nih.gov/29269411