Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Devin A Boyles"'
Autor:
Cynthia M McMillen, Devin A Boyles, Stefan G Kostadinov, Ryan M Hoehl, Madeline M Schwarz, Joseph R Albe, Matthew J Demers, Amy L Hartman
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 10, p e0010898 (2022)
Rift Valley fever (RVF) is a disease of animals and humans associated with abortions in ruminants and late-gestation miscarriages in women. Here, we use a rat model of congenital RVF to identify tropisms, pathologies, and immune responses in the plac
Externí odkaz:
https://doaj.org/article/252dffdec9d24454814de48ee8408d52
Autor:
Henry Ma, Joseph R Albe, Theron Gilliland, Cynthia M McMillen, Christina L Gardner, Devin A Boyles, Emily L Cottle, Matthew D Dunn, Jeneveve D Lundy, Noah Salama, Katherine J O'Malley, Ivona Pandrea, Tobias Teichert, Stacey Barrick, William B Klimstra, Amy L Hartman, Douglas S Reed
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1009946 (2022)
Venezuelan equine encephalitis virus (VEEV) is a positively-stranded RNA arbovirus of the genus Alphavirus that causes encephalitis in humans. Cynomolgus macaques are a relevant model of the human disease caused by VEEV and are useful in exploring pa
Externí odkaz:
https://doaj.org/article/a9ae6f80485742ccbbc0ae30019f063d
Autor:
Joseph R Albe, Henry Ma, Theron H Gilliland, Cynthia M McMillen, Christina L Gardner, Devin A Boyles, Emily L Cottle, Matthew D Dunn, Jeneveve D Lundy, Katherine J O'Malley, Noah Salama, Aaron W Walters, Ivona Pandrea, Tobias Teichert, William B Klimstra, Douglas S Reed, Amy L Hartman
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009308 (2021)
Aerosol exposure to eastern equine encephalitis virus (EEEV) can trigger a lethal viral encephalitis in cynomolgus macaques which resembles severe human disease. Biomarkers indicative of central nervous system (CNS) infection by the virus and lethal
Externí odkaz:
https://doaj.org/article/148107b18d2d4b4295040268973f0ef0
Autor:
Joseph R Albe, Devin A Boyles, Aaron W Walters, Michael R Kujawa, Cynthia M McMillen, Douglas S Reed, Amy L Hartman
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007833 (2019)
Rift Valley fever virus (RVFV) causes severe disease in livestock concurrent with zoonotic transmission to humans. A subset of people infected with RVFV develop encephalitis, and significant gaps remain in our knowledge of how RVFV causes pathology i
Externí odkaz:
https://doaj.org/article/e0c25f150c4c4c20910536b32320f6cd
Autor:
Cynthia M. McMillen, Devin A. Boyles, Stefan G. Kostadinov, Ryan M. Hoehl, Madeline M. Schwarz, Joseph R. Albe, Matthew J. Demers, Amy L. Hartman
Rift Valley fever (RVF) is a disease of animals and humans associated with abortions in ruminants and, more recently, late-gestation miscarriages in African women. Here, we use a rat model of congenital RVF to identify cellular tropism, pathology, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e01f781a370b3ba417fd9357e7ad963
https://doi.org/10.1101/2022.02.25.481831
https://doi.org/10.1101/2022.02.25.481831
Autor:
Austin B. Moyle, Daisy W. Leung, Safder Ganaie, Michael R. Kujawa, Devin A. Boyles, Xiaoxia Cui, Takeshi Egawa, Aidan R. Cole, David A. Price, Wenjie Wang, Monica F. Sentmanat, Michael L. Gross, Ryan M. Hoehl, Herbert W. Virgin, Gaya K. Amarasinghe, Sachdev S. Sidhu, Amy L. Hartman, John G. Doench, Cynthia M. McMillen, Anita K. McElroy, Annie X. Feng, Matthew Demers, Sean P. J. Whelan, Joan Teyra, Tom J. Brett, Anthony Orvedahl, Shane Miersch, Nawneet Mishra, Joseph R. Albe, Madeline M. Schwarz, Nicole D. Wagner, Zachary T. Koenig, Lia Cardarelli, Sarah H. Stubbs
Publikováno v:
Cell
Rift Valley Fever Virus (RVFV) is a zoonotic pathogen with pandemic potential. RVFV entry is mediated by the viral glycoprotein (Gn), but host entry factors remain poorly defined. Our genome-wide CRISPR screen identified low-density lipoprotein recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4526e72964ff21055ddcb4d8d6c2fff1
https://europepmc.org/articles/PMC8786218/
https://europepmc.org/articles/PMC8786218/
Autor:
Katherine J. O’Malley, Joseph R. Albe, Matthew D. Dunn, Emily L. Cottle, Cynthia M. McMillen, Ivona Pandrea, Henry Ma, Noah Salama, William B. Klimstra, Tobias Teichert, Stacey Barrick, Theron Gilliland, Jeneveve D. Lundy, Douglas S. Reed, Devin A. Boyles, Christina L. Gardner, Amy L. Hartman
Publikováno v:
PLoS pathogens. 18(6)
Venezuelan equine encephalitis virus (VEEV) is a positively-stranded RNA arbovirus of the genus Alphavirus that causes encephalitis in humans. Cynomolgus macaques are a relevant model of the human disease caused by VEEV and are useful in exploring pa
Autor:
Cynthia M. McMillen, Amy L. Hartman, Katherine J. O’Malley, Joseph R. Albe, Madeline M. Schwarz, Douglas S. Reed, Devin A. Boyles
Publikováno v:
The Journal of General Virology
The zoonotic emerging Rift Valley fever virus (RVFV) causes sporadic disease in livestock and humans throughout Africa and the Saudi Arabian peninsula. Infection of people with RVFV can occur through mosquito bite or mucosal exposure during butcherin
Autor:
Amy L. Hartman, Cynthia M. McMillen, Carolyn B. Coyne, Joseph R. Albe, Michael R. Kujawa, Jeffrey F. Bonadio, Nitin Arora, Devin A. Boyles
Publikováno v:
Science Advances
Rift Valley fever virus infection of pregnant rats results in fetal infection and death, even in dams with no signs of illness.
Rift Valley fever virus (RVFV) infections in pregnant livestock cause high rates of fetal demise; miscarriage in preg
Rift Valley fever virus (RVFV) infections in pregnant livestock cause high rates of fetal demise; miscarriage in preg
Autor:
Tobias Teichert, Theron Gilliland, Joseph R. Albe, William B. Klimstra, Henry Ma, Douglas S. Reed, Devin A. Boyles, Amy L. Hartman, Cynthia M. McMillen, Ivona Pandrea, Jeneveve D. Lundy, Emily L. Cottle, Christina L. Gardner, Matthew D. Dunn, Noah Salama, Aaron W. Walters, Katherine J. O’Malley
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009308 (2021)
PLoS Pathogens
PLoS Pathogens
Aerosol exposure to eastern equine encephalitis virus (EEEV) can trigger a lethal viral encephalitis in cynomolgus macaques which resembles severe human disease. Biomarkers indicative of central nervous system (CNS) infection by the virus and lethal