Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Devika B."'
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-26 (2023)
Abstract Background Much in vitro research on the applicability of gold nanoparticles (GNPs) in cancer treatment has been focused on two-dimensional (2D) monolayer models. To improve this, we explored the effect of the combination of GNPs and docetax
Externí odkaz:
https://doaj.org/article/36c7455df08742308a2e06625ffab284
Autor:
Abdulaziz Alhussan, Nolan Jackson, Norman Chow, Ermias Gete, Nicole Wretham, Nancy Dos Santos, Wayne Beckham, Cheryl Duzenli, Devika B. Chithrani
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 713 (2024)
This research underscores the potential of combining nanotechnology with conventional therapies in cancer treatment, particularly for challenging cases like pancreatic cancer. We aimed to enhance pancreatic cancer treatment by investigating the syner
Externí odkaz:
https://doaj.org/article/da12d4fe204b42e1b9d76ee5d42418a7
Publikováno v:
Molecules, Vol 29, Iss 11, p 2438 (2024)
Radiotherapy is an essential component of the treatment regimens for many cancer patients. Despite recent technological advancements to improve dose delivery techniques, the dose escalation required to enhance tumor control is limited due to the inev
Externí odkaz:
https://doaj.org/article/922d5ef7590f471e888beab73f0c8e2b
Autor:
Kyle Bromma, Nancy Dos Santos, Ingrid Barta, Abraham Alexander, Wayne Beckham, Sunil Krishnan, Devika B. Chithrani
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Recent clinical trials show docetaxel (DTX), given in conjunction with radiation therapy (RT) and androgen suppression, improves survival in high-risk prostate cancer. Addition of gold nanoparticles (GNPs) to this current DTX/RT protocol is
Externí odkaz:
https://doaj.org/article/e49fc97f980f416e966cd2ae708ed4c6
Publikováno v:
Pharmaceutics, Vol 16, Iss 2, p 175 (2024)
Cancer is defined as the uncontrolled proliferation of heterogeneous cell cultures in the body that develop abnormalities and mutations, leading to their resistance to many forms of treatment. Left untreated, these abnormal cell growths can lead to d
Externí odkaz:
https://doaj.org/article/57ed3f81d1a841489b059631ab4a733a
Autor:
Abdulaziz Alhussan, Kyle Bromma, Ece Pinar Demirci Bozdoğan, Andrew Metcalfe, Joanna Karasinska, Wayne Beckham, Abraham S. Alexander, Daniel J. Renouf, David F. Schaeffer, Devika B. Chithrani
Publikováno v:
Current Oncology, Vol 28, Iss 3, Pp 1962-1979 (2021)
Pancreatic cancer is one of the deadliest types of cancer, with a five-year survival rate of only 10%. Nanotechnology offers a novel perspective to treat such deadly cancers through their incorporation into radiotherapy and chemotherapy. However, the
Externí odkaz:
https://doaj.org/article/83da062e6af1442aabd6135833a9a5a2
Publikováno v:
Cancer Nanotechnology, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Successful integration of nanotechnology into the current paradigm of cancer therapy requires proper understanding of the interface between nanoparticles (NPs) and cancer cells, as well as other key components within the tumor microenvironme
Externí odkaz:
https://doaj.org/article/e7417468d24443228b5e383d723f8c58
Autor:
Nolan Jackson, Abdulaziz Alhussan, Kyle Bromma, David Jay, James C. Donnelly, Frederick G. West, Afsaneh Lavasanifar, Michael Weinfeld, Wayne Beckham, Devika B. Chithrani
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2795 (2022)
Radiation therapy (RT) is frequently used to locally treat tumors. One of the major issues in RT is normal tissue toxicity; thus, it is necessary to limit dose escalation for enhanced local control in patients that have locally advanced tumors. Integ
Externí odkaz:
https://doaj.org/article/a9ada600b46941b1bddf75ccea8a198c
Autor:
Kyle Bromma, Kristy Rieck, Jayesh Kulkarni, Connor O’Sullivan, Wonmo Sung, Pieter Cullis, Jan Schuemann, Devika B. Chithrani
Publikováno v:
Cancer Nanotechnology, Vol 10, Iss 1, Pp 1-17 (2019)
Abstract Background Radiotherapy is commonly used for treating cancer. Novel sensitizers, such as gold nanoparticles (GNPs), are being used to enhance the local radiation dose. It is not known how the uptake and radiation dose enhancement of GNPs var
Externí odkaz:
https://doaj.org/article/38df13f482774eaf907c54067bc376fe
Autor:
Celina Yang, Kyle Bromma, Caterina Di Ciano-Oliveira, Gaetano Zafarana, Monique van Prooijen, Devika B. Chithrani
Publikováno v:
Cancer Nanotechnology, Vol 9, Iss 1, Pp 1-14 (2018)
Abstract Background The combined use of radiation therapy and chemotherapy is commonly being used in cancer treatment. The side effects of the treatment can be further minimized through targeted delivery of anticancer drugs and local enhancement of t
Externí odkaz:
https://doaj.org/article/0631bb869e1846829f92ee58393d7ed1