Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Devi SenGupta"'
Autor:
Mohamed Abdel-Mohsen, Steven Deeks, Leila Giron, Kai Ying Hong, Aaron Goldman, Liao Zhang, Susie S. Y. Huang, Donovan Verrill, Susan Guo, Lisa Selzer, Christiaan R. de Vries, Elena Vendrame, Devi SenGupta, Jeffrey J. Wallin, Yanhui Cai
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAntiretroviral therapy (ART) for HIV-1 treatment has improved lifespan but requires lifelong adherence for people living with HIV (PLWH), highlighting the need for a cure. Evaluation of potential cure strategies requires analytic treatment
Externí odkaz:
https://doaj.org/article/095bab4f17fa480d8c63f5de87ce6252
Autor:
Susan Pereira Ribeiro, Jeffrey M Milush, Edecio Cunha-Neto, Esper G Kallas, Jorge Kalil, Luiz Felipe D Passero, Peter W Hunt, Steven G Deeks, Douglas F Nixon, Devi SenGupta
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176509 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0166759.].
Externí odkaz:
https://doaj.org/article/30d43e76ec9a45649e36422e656323c2
Autor:
Susan Pereira Ribeiro, Jeffrey M Milush, Edecio Cunha-Neto, Esper G Kallas, Jorge Kalil, Luiz Felipe D Passero, Peter W Hunt, Steven G Deeks, Douglas F Nixon, Devi SenGupta
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166759 (2016)
Chronic HIV infection is characterized by increased immune activation and immunosenescence. p16 INK4a (p16) is a member of the cyclin-dependent kinase antagonist family that inhibits cellular proliferation, and its protein expression increases during
Externí odkaz:
https://doaj.org/article/6a1a97a157604c5983bf7c1306582e2c
Autor:
Ravi Tandon, Maria T M Giret, Devi Sengupta, Vanessa A York, Andrew A Wiznia, Michael G Rosenberg, Esper G Kallas, Lishomwa C Ndhlovu, Douglas F Nixon
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45733 (2012)
As perinatally HIV-1-infected children grow into adolescents and young adults, they are increasingly burdened with the long-term consequences of chronic HIV-1 infection, with long-term morbidity due to inadequate immunity. In progressive HIV-1 infect
Externí odkaz:
https://doaj.org/article/7b75b4c258804f33ae86cf305ecdf7f5
Autor:
Christopher E Ormsby, Devi Sengupta, Ravi Tandon, Steven G Deeks, Jeffrey N Martin, R Brad Jones, Mario A Ostrowski, Keith E Garrison, Joel A Vázquez-Pérez, Gustavo Reyes-Terán, Douglas F Nixon
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e41021 (2012)
Human endogenous retroviruses (HERV) are remnants of ancestral retroviral infections integrated into the germ line, and constitute approximately 8% of the genome. Several autoimmune disorders, malignancies, and infectious diseases such as HIV-1 are a
Externí odkaz:
https://doaj.org/article/d69162197cad401db23a89d82c0653ab
Autor:
Monique Nijhuis, Steven G. Deeks, Richard Dunham, Marein A. W. P. de Jong, Marein de Jong, Thanyawee Puthanakit, Mirko Paiardini, Santiago Perez Patrigeon, Krista L. Dong, Jan van Lunzen, Luke Jasenosky, Jessica Salzwedel, Simon Collins, Katharine J. Bar, Frank Mardarelli, Jeffrey T. Safrit, Jeremy Sugarman, Alex Schneider, Nancie M. Archin, Zaza M. Ndhlovu, Joel N. Blankson, Zabrina L. Brumme, Hans-Peter Kiem, Gaerolwe Masheto, Beatriz Mothe, Karine Dubé, Katherine Luzuriaga, Jennifer Power, Sarah Fidler, Richard Jefferys, Fu Sheng Wang, Jeff Taylor, Kumitaa Theva Das, Boro Dropulic, Kai Deng, Devi SenGupta, Sharon Lewin, Marina Caskey, Susana T. Valente, Siegfried Schwarze, Nicolas Chomont, R. Brad Jones, Ole S. Søgaard, Paula M. Cannon, Olivier Lambotte, Edward Nelson Kankaka, Gabriela Turk, Christina Antoniadi, Udom Likhitwonnawut, Caroline T. Tiemessen, Pablo Tebas, Rosanne Lamplough, Cissy Kityo, Fernanda Heloise Côrtes, Melannie Ott, Rose Nabatanzi, Oguzhan Latif Nuh, Mitch Matoga, Linos Vandekerckhove, J. Victor Garcia, Thumbi Ndung'u, Bonnie J. Howell, Aurelio Orta-Resendiz, Ricardo Sobhie Diaz, Michael Louella, Ann Chahroudi, Deborah Persaud, Stephan Dressler, Josephine Nabukenya, Sharon R Lewin
Publikováno v:
Nature Medicine. 27:2085-2098
Despite the success of antiretroviral therapy (ART) for people living with HIV, lifelong treatment is required and there is no cure. HIV can integrate in the host genome and persist for the life span of the infected cell. These latently infected cell
Autor:
Devi SenGupta, Pottage John C, Moses Supercharger Nsubuga, Thumbi Ndung'u, Timothy Attoye, Mitchell Warren, David Ripin, Rowena Johnston, Karine Dubé, Brian P. Doehle, Izukanji Sikazwe, Mark Dybul, Joseph M. McCune, Sharon R Lewin, Rosanne Lamplough, Steven G. Deeks, Cathy Bansbach, James F. Rooney, Adam Jiang, Gary J Nabel
Publikováno v:
Lancet HIV
The Lancet. HIV
The Lancet. HIV
Summary Developing a cure for HIV is a global priority. Target product profiles are a tool commonly used throughout the drug development process to align interested parties around a clear set of goals or requirements for a potential product. Three di
Autor:
John W. Mellors, Brian Moldt, Moti Ramgopal, Terri Wrin, April L. Ferre, Edwin DeJesus, Yanhui Cai, Barbara L. Shacklett, Romas Geleziunas, Peter Shalit, Norman G. Jones, Elena Vendrame, Anthony Mills, Rita Humeniuk, Steven G. Deeks, Devi SenGupta, Jeffrey M. Milush, Diana M. Brainard, Greg M. Laird, Jeffrey Wallin, Cynthia Brinson, Rebecca Begley, Liao Zhang, Susan Guo
Publikováno v:
Science translational medicine. 13(599)
Toll-like receptor 7 (TLR7) agonists, in combination with other therapies, can induce sustained control of simian-human immunodeficiency virus (SHIV) or simian immunodeficiency virus (SIV) in nonhuman primates. Here, we report the results of a random
Autor:
Hiba Graham, Terri Wrin, Joshua C. Cyktor, Michael F. Para, Gregory M. Laird, Heena Patel, Jillian Boice, Rita Humeniuk, Jeffrey Wallin, Romas Geleziunas, Cynthia Brinson, Dianna Koontz, Diana M. Brainard, John W. Mellors, Jana L. Jacobs, Constance A. Benson, Polina German, Susan Guo, Sharon A. Riddler, Rebecca Begley, Moti Ramgopal, Devi SenGupta, Edwin DeJesus, Liao Zhang, Anthony Mills
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 72(11)
Background Treatment with vesatolimod, an investigational, oral, toll-like receptor 7 (TLR7) agonist, leads to sustained viral remission in some non-human primates when combined with anti-envelope antibodies or therapeutic vaccines. We report results
Autor:
Frank A. Post, Cynthia Brinson, Debbie Hagins, Hans-Jürgen Stellbrink, Claudia Martorell, B. Rashbaum, Morales-Ramirez J, H Liu, Chloe Orkin, Eric S. Daar, Y P Liu, Das M, Melanie A. Thompson, Sean E Collins, Devi SenGupta, Anthony Mills, Olayemi Osiyemi, Edwin DeJesus, Danielle Porter
Publikováno v:
HIV Medicine
Objectives The single‐tablet regimen rilpivirine, emtricitabine and tenofovir alafenamide (RPV/FTC/TAF) for treatment of HIV‐1‐infected adults was approved based on bioequivalence. We assessed the clinical efficacy, safety and tolerability of s