Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Devesh M, Sawant"'
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109311- (2024)
Summary: Cross-coupling azide and isocyanide have recently gained recognition as ideal methods for efficiently synthesizing asymmetric carbodiimides. This reaction exhibits high reaction rates, efficiency, and favorable atom/step/redox economy. It en
Externí odkaz:
https://doaj.org/article/1a0dc9860c094b43adcc1c3f333212d2
Publikováno v:
Current Computer-Aided Drug Design. 19:382-390
Background: Amphotericin B is a gold-standard drug, particularly for the treatment of systemic fungal infections. However, its low solubility and permeability limit its application. To improve its bioavailability, AmB may be conjugated with various w
Autor:
Elagandhula Sathish, Ashis Kumar Gupta, null Deeksha, Sandeep Kumar Mishra, Devesh M. Sawant, Ritesh Singh
Publikováno v:
The Journal of Organic Chemistry. 87:14168-14176
Herein, we report a highly efficient and unprecedented approach for heteroarylation of congested α-bromoamides via electrophilic aromatic substitution of imidazo-heteroarenes and indolizines under mild reaction conditions (room temperature, metal, a
Autor:
Avadh Biharee, Arpita Yadav, Kailash Jangid, Yogesh Singh, Swanand Kulkarni, Devesh M. Sawant, Pradeep Kumar, Suresh Thareja, Akhlesh Kumar Jain
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-12
Publikováno v:
Current Topics in Medicinal Chemistry. 22:1571-1592
Abstract: Over the last 50 years, the number of patients with mycotic infections has gradually in-creased. Amphotericin-B is a gold-standard drug used in serious systemic fungal infections. How-ever, limited solubility and permeability are challengin
Autor:
Elagandhula, Sathish, Arshad J, Ansari, Gaurav, Joshi, Akansha, Pandit, Monika, Shukla, Neha, Kumari, Ashoke, Sharon, Ved Prakash, Verma, Devesh M, Sawant
Publikováno v:
Organicbiomolecular chemistry. 20(23)
In the current research, we envisaged the synthesis of bis-heterocycles containing the dihydroisoxazole ring by [3 + 2] cycloaddition of VECs (vinyl ethylene carbonates) and nitrile oxides, assisted by a Pd catalyst. Herein we explored hydroximoyl ch
Autor:
Gaurav Joshi, Sandeep Singh, Raj Kumar, Arshad J. Ansari, Praveen Sharma, Ramesh K. Metre, Vijai K. Agnihotri, Devesh M. Sawant, Chanchayya Gupta Chandaluri, Antim K. Maurya
Publikováno v:
The Journal of Organic Chemistry. 84:3817-3825
A Pd-catalyzed cascade reaction of four versatile privileged synthons is described. The sequential reaction involves the formation of five new chemical bonds by concatenating three distinct chemical steps. One of the derivatives exhibited absorption
Autor:
Vijai K. Agnihotri, Prasad V. Bharatam, Antim K. Maurya, Ashoke Sharon, Devesh M. Sawant, Aabid Abdullah Wani, Sarika Verma, Arshad J. Ansari
Publikováno v:
Chemical Communications. 55:14825-14828
A serendipitous discovery of [1,3]-sulfonyl migration has been made in the two-component reaction of azomethine imine and allenoates. Current methodology involving N-S bond cleavage and C-S bond formation provided easy access to biologically importan
Autor:
Antim K. Maurya, Arshad J. Ansari, Anita Kumawat, Ramdas S. Pathare, Ram T. Pardasani, Vijai K. Agnihotri, Devesh M. Sawant, Ramesh K. Metre, Ashoke Sharon, Sarika Verma, Rahul Joshi
Publikováno v:
New Journal of Chemistry. 43:13721-13724
Pd-Catalyzed sequential reactions to afford skeletally diverse molecules are described. The reaction involved azomethine imine formation and a cyclocondensation reaction as individual steps. The methodology provides excellent regio- and stereocontrol
Autor:
Elagandhula Sathish, Manmohan Sharma, Arshad J. Ansari, Gaurav Joshi, Akansha Pandit, Monika Shukla, Neha Kumari, Ashoke Sharon, Ved Prakash Verma, Devesh M. Sawant
Publikováno v:
Organic & Biomolecular Chemistry. 20:9241-9241
Correction for ‘Pd-Catalysed [3 + 2]-cycloaddition towards the generation of bioactive bis-heterocycles/identification of COX-2 inhibitors via in silico analysis’ by Elagandhula Sathish et al., Org. Biomol. Chem., 2022, 20, 4746–4752, https://d