Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Devendra B. Srivastava"'
Autor:
Kylie S. Chew, Robert C. Wells, Arash Moshkforoush, Darren Chan, Kendra J. Lechtenberg, Hai L. Tran, Johann Chow, Do Jin Kim, Yaneth Robles-Colmenares, Devendra B. Srivastava, Raymond K. Tong, Mabel Tong, Kaitlin Xa, Alexander Yang, Yinhan Zhou, Padma Akkapeddi, Lakshman Annamalai, Kaja Bajc, Marie Blanchette, Gerald Maxwell Cherf, Timothy K. Earr, Audrey Gill, David Huynh, David Joy, Kristen N. Knight, Diana Lac, Amy Wing-Sze Leung, Katrina W. Lexa, Nicholas P. D. Liau, Isabel Becerra, Mario Malfavon, Joseph McInnes, Hoang N. Nguyen, Edwin I. Lozano, Michelle E. Pizzo, Elysia Roche, Patricia Sacayon, Meredith E. K. Calvert, Richard Daneman, Mark S. Dennis, Joseph Duque, Kapil Gadkar, Joseph W. Lewcock, Cathal S. Mahon, René Meisner, Hilda Solanoy, Robert G. Thorne, Ryan J. Watts, Y. Joy Yu Zuchero, Mihalis S. Kariolis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Brain exposure of systemically administered biotherapeutics is highly restricted by the blood-brain barrier (BBB). Here, we report the engineering and characterization of a BBB transport vehicle targeting the CD98 heavy chain (CD98hc or SLC3
Externí odkaz:
https://doaj.org/article/c0dcaba8ffc04890ade94c8b75b21509
Autor:
Kylie S. Chew, Robert C. Wells, Arash Moshkforoush, Darren Chan, Kendra J. Lechtenberg, Hai L. Tran, Johann Chow, Do Jin Kim, Yaneth Robles-Colmenares, Devendra B. Srivastava, Raymond K. Tong, Mabel Tong, Kaitlin Xa, Alexander Yang, Yinhan Zhou, Padma Akkapeddi, Lakshman Annamalai, Kaja Bajc, Marie Blanchette, Gerald Maxwell Cherf, Timothy K. Earr, Audrey Gill, David Huynh, David Joy, Kristen N. Knight, Diana Lac, Amy Wing-Sze Leung, Katrina W. Lexa, Nicholas P. D. Liau, Isabel Becerra, Mario Malfavon, Joseph McInnes, Hoang N. Nguyen, Edwin I. Lozano, Michelle E. Pizzo, Elysia Roche, Patricia Sacayon, Meredith E. K. Calvert, Richard Daneman, Mark S. Dennis, Joseph Duque, Kapil Gadkar, Joseph W. Lewcock, Cathal S. Mahon, René Meisner, Hilda Solanoy, Robert G. Thorne, Ryan J. Watts, Y. Joy Yu Zuchero, Mihalis S. Kariolis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a16cb8fb950d46f9ab274a050ec42452
Autor:
Ryan J. Watts, Kathryn M. Monroe, Junhua Wang, Melina Lenser, Jennifer Hsiao-Nakamoto, Hoang Nguyen, Todd P. Logan, Do Jin Kim, Fen Huang, Ritesh Ravi, Gilbert Di Paolo, Anil Rana, Kannan Gunasekaran, Yaneth Robles-Colmenares, Gerald M. Cherf, Buyankhishig Tsogtbaatar, Ceyda Llapashtica, Kirk R. Henne, Hilda Solanoy, Pascal E. Sanchez, Yashas Rajendra, Mihalis Kariolis, Ray Lieh Yoon Low, Roni Chau, Laralynne Przybyla, Michelle E. Pizzo, Chi-Lu Chiu, Meng Fang, Anastasia G. Henry, Giuseppe Astarita, Mark S. Dennis, Adam L. Boxer, Sarah L. DeVos, Sonnet S. Davis, Hilary W. Heuer, René Meisner, Joseph W. Lewcock, Devendra B. Srivastava, Bradley F. Boeve, Meredith E. K. Calvert, Katrina W. Lexa, Rachel Prorok, Lukas L. Skuja, Dolores Diaz, Akhil Bhalla, Matthew Simon, Jung H. Suh, Ankita Srivastava, Timothy K. Earr, Howard J. Rosen, Joseph Duque, Bettina Van Lengerich, Elizabeth W. Sun
Publikováno v:
Cell
Cell, vol 184, iss 18
Cell, vol 184, iss 18
GRN mutations cause frontotemporal dementia (GRN-FTD) due to deficiency in progranulin (PGRN), a lysosomal and secreted protein with unclear function. Here, we found that Grn(−/−) mice exhibit a global deficiency in bis(monoacylglycero)phosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e8760616b55660b5a69ea73b7ad6da
https://europepmc.org/articles/PMC8489356/
https://europepmc.org/articles/PMC8489356/
Autor:
Frank DiMaio, Katryn J. Stacey, Yang Li, Parimala R. Vajjhala, Tian-Min Fu, Richard M. Siegel, Devendra B. Srivastava, Zongli Li, Hao Wu, Edward H. Egelman, Alvin Lu, Pawel A. Penczek, Anthony C. Cruz
Caspase-8 activation can be triggered by death receptor-mediated formation of the death-inducing signaling complex (DISC) and by the inflammasome adaptor ASC. Caspase-8 assembles with FADD at the DISC and with ASC at the inflammasome through its tand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ba3170b664d453fd7244955ea889cd
https://europepmc.org/articles/PMC5089849/
https://europepmc.org/articles/PMC5089849/
Autor:
Devendra B. Srivastava, Seth A. Darst
Transcription-repair coupling factor (TRCF; the product of the mfd gene) is a widely conserved bacterial protein that couples DNA repair with transcription. TRCF recognizes RNA polymerase stalled at a noncoding lesion in the DNA template strand, uses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcc06250ebfdc7f263f18f6bb53990c
https://europepmc.org/articles/PMC3031748/
https://europepmc.org/articles/PMC3031748/