Zobrazeno 1 - 10
of 386
pro vyhledávání: '"Developmental Biology/Cell Differentiation"'
Autor:
Magdalena Paolino, Georg A. Holländer, Jason Mr Gill, Elisabeth Fayard, Debby Hynx, Brian A. Hemmings
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e992 (2007)
PLoS ONE
PLoS ONE
BACKGROUND: The thymus constitutes the primary lymphoid organ for the majority of T cells. The phosphatidyl-inositol 3 kinase (PI3K) signaling pathway is involved in lymphoid development. Defects in single components of this pathway prevent thymocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4575d8cf26d1b231211908d4af7c65c1
https://doi.org/10.1371/journal.pone.0000992
https://doi.org/10.1371/journal.pone.0000992
Autor:
Corina Anastasaki, John Maule, Robert N. Kelsh, Michal Grzmil, E. Elizabeth Patton, Daniel J. Whiting, James F. Amatruda, Chris J. Norbury
Publikováno v:
PLoS ONE, Vol 2, Iss 9, p e959 (2007)
Grzmil, M, Whiting, D, Maule, J, Anastasaki, C, Amatruda, J F, Kelsh, R N, Norbury, C J & Patton, E E 2007, ' The INT6 cancer gene and MEK signaling pathways converge during zebrafish development ', PLoS ONE, vol. 2, no. 9, pp. e959 . https://doi.org/10.1371/journal.pone.0000959
PLoS ONE
Grzmil, M, Whiting, D, Maule, J, Anastasaki, C, Amatruda, J F, Kelsh, R N, Norbury, C J & Patton, E E 2007, ' The INT6 cancer gene and MEK signaling pathways converge during zebrafish development ', PLoS ONE, vol. 2, no. 9, pp. e959 . https://doi.org/10.1371/journal.pone.0000959
PLoS ONE
Background. Int-6 (integration site 6) was identified as an oncogene in a screen of tumorigenic mouse mammary tumor virus (MMTV) insertions. INT6 expression is altered in human cancers, but the precise role of disrupted INT6 in tumorigenesis remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b25a4a1ed046756943cdb285d8fd0f
https://ora.ox.ac.uk/objects/uuid:d1bf24fc-8258-4e28-91d1-d2eb5571c72e
https://ora.ox.ac.uk/objects/uuid:d1bf24fc-8258-4e28-91d1-d2eb5571c72e
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 12, p e8392 (2009)
PLoS ONE, Vol 4, Iss 12, p e8392 (2009)
Nuclear receptors (NRs) comprise a family of ligand-regulated transcription factors that control diverse critical biological processes including various aspects of brain development. Eighteen NR genes exist in the Drosophila genome. To explore their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b362b3e322c40076fba27da31e8221b
https://ora.ox.ac.uk/objects/uuid:ae2d2262-095f-4ca5-9346-a14788c1989d
https://ora.ox.ac.uk/objects/uuid:ae2d2262-095f-4ca5-9346-a14788c1989d
Autor:
Steve J. Charette, Michael O. Hengartner, Ralf Schnabel, Günter Lochnit, Juan Cabello, Ufuk Günesdogan, Lukas J. Neukomm, Katharina Burkart
Publikováno v:
PLoS Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Biology, Vol 8, Iss 2, p e1000297 (2010)
Europe PubMed Central
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS Biology, Vol 8, Iss 2, p e1000297 (2010)
Europe PubMed Central
This is an open-access article distributed under the terms of the Creative Commons Attribution License.-- et al.
Wnt signalling pathways have extremely diverse functions in animals, including induction of cell fates or tumours, guidance of cell
Wnt signalling pathways have extremely diverse functions in animals, including induction of cell fates or tumours, guidance of cell
Publikováno v:
PLoS Biology
PLoS Biology, Vol 9, Iss 4, p e1000609 (2011)
PLoS Biology, Vol 9, Iss 4, p e1000609 (2011)
Retinoic acid (RA) is essential for the generation of GABAergic inhibitory neurons in the mouse forebrain, and RA treatment of embryonic stem cells induces the production of GABAergic neurons.
Although retinoic acid (RA) has been implicated as a
Although retinoic acid (RA) has been implicated as a
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001328 (2011)
PLoS Genetics
PLoS Genetics
Asymmetrical segregation of differentiated sister chromatids is thought to be important for cellular differentiation in higher eukaryotes. Similarly, in fission yeast, cellular differentiation involves the asymmetrical segregation of a chromosomal im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa80bb9a0b9af69d4f89730a0bc9798
http://wrap.warwick.ac.uk/34580/1/WRAP_Sayrac_Identification_Novel_Type_.pdf
http://wrap.warwick.ac.uk/34580/1/WRAP_Sayrac_Identification_Novel_Type_.pdf
Autor:
Elizabeth M. Hartfield, James B. Uney, Maeve A. Caldwell, Colin P. J. Glover, Federica Rinaldi, Liang-Fong Wong
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e14746 (2011)
PLoS ONE
PLoS ONE
BACKGROUND: Gap junction communication has been shown in glial and neuronal cells and it is thought they mediate inter- and intra-cellular communication. Connexin 36 (Cx36) is expressed extensively in the developing brain, with levels peaking at P14
Publikováno v:
PLoS Biology, Vol 9, Iss 2, p e1000593 (2011)
PLoS Biology
PLoS Biology, Vol 9, Iss 2, p e1001018 (2011)
e1000593
PLoS Biology
PLoS Biology, Vol 9, Iss 2, p e1001018 (2011)
e1000593
In frog and fish embryos, SNW1 is a protein required for the spatio-temporal activity of BMP signaling necessary for neural plate border formation and specification of neural crest tissue.
Bone morphogenetic protein (BMP) gradients provide posit
Bone morphogenetic protein (BMP) gradients provide posit
Autor:
Marcus-Oliver Schupp, Ramani Ramchandran, Indu Remadevi, Kallal Pramanik, Ganesh V. Samant, Chang Zoon Chun, George A. Wilkinson
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14732 (2011)
PLoS ONE
PLoS ONE
Background Vasculogenesis, the de novo formation of blood vessels from precursor cells is critical for a developing embryo. However, the signals and events that dictate the formation of primary axial vessels remain poorly understood. Methodology/Prin
Autor:
Jeanne F. Loring, Gabriel Nistor, Louise C. Laurent, David Ferguson, Hans S. Keirstead, L. S. Agapova, Magdalene J. Seiler, Nikolay A. Turovets, Gulsah Altun, Julie V. Harness
Publikováno v:
Harness, Julie V.; Turovets, Nikolay A.; Seiler, Magdalene J.; Nistor, Gabriel; Altun, Gulsah; Agapova, Larissa S.; et al.(2011). Equivalence of Conventionally-Derived and Parthenote-Derived Human Embryonic Stem Cells. PLoS ONE, 6(1). UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1t30n65h
PLoS ONE, Vol 6, Iss 1, p e14499 (2011)
PLoS ONE
PLoS ONE, Vol 6, Iss 1, p e14499 (2011)
PLoS ONE
Background As human embryonic stem cell (hESC) lines can be derived via multiple means, it is important to determine particular characteristics of individual lines that may dictate the applications to which they are best suited. The objective of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d90fa8f565bb6c1c6bd87380c30f90
http://www.escholarship.org/uc/item/1t30n65h
http://www.escholarship.org/uc/item/1t30n65h