Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Development at A Glance"'
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The lateral plate mesoderm (LPM) forms the progenitor cells that constitute the heart and cardiovascular system, blood, kidneys, smooth muscle lineage and limb skeleton in the developing vertebrate embryo. Despite this central role in development and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee49a47c19e2a9fa35d71be10a555752
https://pubmed.ncbi.nlm.nih.gov/32561665
https://pubmed.ncbi.nlm.nih.gov/32561665
Autor:
Denis Duboule, Christopher Chase Bolt
Publikováno v:
Development (Cambridge, England)
Regulatory landscapes have been defined in vertebrates as large DNA segments containing diverse enhancer sequences that produce coherent gene transcription. These genomic platforms integrate multiple cellular signals and hence can trigger pleiotropic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32cf11493724be7425473ab60de0f8e
https://doi.org/10.1242/dev.171736
https://doi.org/10.1242/dev.171736
Autor:
James M. Wells, Heather A. McCauley
Publikováno v:
Development. 144:958-962
Pluripotent stem cell (PSC)-derived organoids are miniature, three-dimensional human tissues generated by the application of developmental biological principles to PSCs in vitro. The approach to generate organoids uses a combination of directed diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db1842bf48130d3238e11714734eac2
https://doi.org/10.1242/dev.140731
https://doi.org/10.1242/dev.140731
Publikováno v:
Development
Collective cell migration is the coordinated movement of a physically connected group of cells and is a prominent driver of development and metastasis. Interactions between cells within migrating collectives, and between migrating cells and other cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc021047578b8604fdf974011440b07
https://doi.org/10.1242/dev.172056
https://doi.org/10.1242/dev.172056
Autor:
Gregg Duester, Norbert B. Ghyselinck
Publikováno v:
Development
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2019, 146 (13), pp.dev167502. ⟨10.1242/dev.167502⟩
Development (Cambridge, England), 2019, 146 (13), pp.dev167502. ⟨10.1242/dev.167502⟩
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2019, 146 (13), pp.dev167502. ⟨10.1242/dev.167502⟩
Development (Cambridge, England), 2019, 146 (13), pp.dev167502. ⟨10.1242/dev.167502⟩
Retinoic acid (RA), a metabolite of retinol (vitamin A), functions as a ligand for nuclear RA receptors (RARs) that regulate development of chordate animals. RA-RARs can activate or repress transcription of key developmental genes. Genetic studies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2950e8692f2b56a5c0419963c2f3e9
https://doi.org/10.1242/dev.167502
https://doi.org/10.1242/dev.167502
Autor:
Kenneth S. Zaret, Makiko Iwafuchi-Doi
Publikováno v:
Development. 143:1833-1837
Distinct combinations of transcription factors are necessary to elicit cell fate changes in embryonic development. Yet within each group of fate-changing transcription factors, a subset called ‘pioneer factors’ are dominant in their ability to en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ac0dec0014f47e7222b5f0bdb1f194
https://doi.org/10.1242/dev.133900
https://doi.org/10.1242/dev.133900
Publikováno v:
Development. 142:1390-1395
Lysophosphatidic acid (LPA) is a bioactive phospholipid that is present in all tissues examined to date. LPA signals extracellularly via cognate G protein-coupled receptors to mediate cellular processes such as survival, proliferation, differentiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd9313a4d1752336e9f1f5a56da469d
https://doi.org/10.1242/dev.121723
https://doi.org/10.1242/dev.121723
Autor:
Paolo Bianco, Pamela Gehron Robey
Publikováno v:
Handbook of Stem Cells
Most bones develop from mesenchymal condensations giving rise to cartilaginous rudiments via a prechondrogenic blastema. The outermost portion of the chondrogenic blastema later evolves into a perichondrium and further into a primitive periosteum at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5005d4c74439bb535b501bd3aabd7d8
https://doi.org/10.1242/dev.102210
https://doi.org/10.1242/dev.102210
Publikováno v:
Development. 141:5-9
Sphingosine 1-phosphate (S1P) is a lipid mediator formed by the metabolism of sphingomyelin. In vertebrates, S1P is secreted into the extracellular environment and signals via G protein-coupled S1P receptors to regulate cell-cell and cell-matrix adhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9bedea6b2da68894094ad007dd12bd3
https://doi.org/10.1242/dev.094805
https://doi.org/10.1242/dev.094805
Publikováno v:
Development. 140:1615-1620
The brassinosteroid (BR) class of steroid hormones regulates plant development and physiology. The BR signal is transduced by a receptor kinase-mediated signal transduction pathway, which is distinct from animal steroid signalling systems. Recent stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc2208554fc844fc55ee43903a9c767
https://doi.org/10.1242/dev.060590
https://doi.org/10.1242/dev.060590