Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Devarajan Karunagaran"'
Publikováno v:
Translational Oncology, Vol 48, Iss , Pp 102063- (2024)
Purpose: The aim of this research was to elucidate the role of miR-34b in cervical cancer progression and the underlying mechanism behind the miR-34b-mediated tumor suppression. The study revealed the role of miR-34b as a senescence inducer and serve
Externí odkaz:
https://doaj.org/article/d1641f8eea7e40539cd38031e0856ef2
Autor:
Prerna Bhalla, Raghunathan Rengaswamy, Devarajan Karunagaran, G. K. Suraishkumar, Swagatika Sahoo
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract The onset of colorectal cancer (CRC) is often attributed to gut bacterial dysbiosis, and thus gut microbiota are highly relevant in devising treatment strategies. Certain gut microbes, like Enterococcus spp., exhibit remarkable anti-neoplast
Externí odkaz:
https://doaj.org/article/73d685684b934b6780b651940d0f5b88
Autor:
Kaushik Neogi, Prashant R. Murumkar, Priyanshu Sharma, Poonam Yadav, Mallika Tewari, Devarajan Karunagaran, Prasanta Kumar Nayak, Mange Ram Yadav
Publikováno v:
Translational Oncology, Vol 19, Iss , Pp 101395- (2022)
Overactivation of Wnt/β-catenin signaling by accumulated β-catenin in the nucleus has been shown to play a crucial role in the etiology of cancer. Interaction of β-catenin with Transcription factor 4 (TCF4) is a key step for the activation of Wnt
Externí odkaz:
https://doaj.org/article/99e36f32cfa74c25a6c58acb867463f2
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120045 (2015)
Cervical cancer is the major cause of cancer related deaths in women, especially in developing countries and Human Papilloma Virus infection in conjunction with multiple deregulated signaling pathways leads to cervical carcinogenesis. TGF-β signalin
Externí odkaz:
https://doaj.org/article/1d30808cef8b428d88ea48e74977857a
Autor:
Siluveru KrishnaPriya, Sonal Omer, Satarupa Banerjee, Devarajan Karunagaran, G. K. Suraishkumar
Publikováno v:
Molecular Genetics and Genomics. 297:1353-1370
Development of colon adenocarcinoma (COAD) metastasis involves several mediators including fluid shear stress (FSS), intracellular ROS levels, and non-coding RNAs. In our present study, we identified and investigated the role of regulatory non-coding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa46435a761d1a7239c7bf9ea5bfe1c
https://doi.org/10.1007/s00438-022-01924-z
https://doi.org/10.1007/s00438-022-01924-z
Autor:
Vidya P Warrier, Anoosha Paruchuri, Sakthivel Ramasamy, Michael M Gromiha, Devarajan Karunagaran
Epidermal Growth Factor Receptor (EGFR) signaling is known to play essential roles in growth and development; nevertheless, overexpression and mutation of EGFR have been reported in several cancers. Non-small cell lung cancer (NSCLC), the most observ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e261944a50d22839726110ac185a6059
https://doi.org/10.1101/2023.01.29.526080
https://doi.org/10.1101/2023.01.29.526080
Autor:
Devarajan Karunagaran, Krishnamurthy Arvind, Latha Durai, Ramshankar Vijayalakshmi, Soundharya Ravindran
Publikováno v:
Molecular Biology Reports. 48:7443-7456
Survival rate of patients affected with anaplastic thyroid carcinoma (ATC) is less than 5% with current treatment. In ATC, BRAFV600E mutation is the major mutation that results in the transformation of normal cells in to an undifferentiated cancer ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450563fcb24f8cad294b37f98e2b8a98
https://doi.org/10.1007/s11033-021-06762-7
https://doi.org/10.1007/s11033-021-06762-7
Publikováno v:
OMICS: A Journal of Integrative Biology. 25:545-566
MicroRNAs (miRNAs) that are mutually modulated by their interacting partners (interactome) are being increasingly noted for their significant role in pathogenesis and treatment of various human cancers. Recently, miRNA interactome dissected with mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fdc294d661a6691f57b2fccf0db1c2
https://doi.org/10.1089/omi.2021.0087
https://doi.org/10.1089/omi.2021.0087
Autor:
K J Sindhu, Devarajan Karunagaran
Publikováno v:
Cancer Research. 83:3774-3774
Background: Cervical cancer is one of the most common cancers in women worldwide, particularly in low- and middle-income countries. Due to low surveillance and late detection, it is one of the major health issues leading to high mortality rates. Micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8caa8cbaaf792c529fa92c57956b10e4
https://doi.org/10.1158/1538-7445.am2023-3774
https://doi.org/10.1158/1538-7445.am2023-3774
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Rhythms in the pseudo-steady state (PSS) levels of reactive species (RS), particularly superoxide and hydroxyl radicals, exist in cancer cells. The RS rhythm characteristics, particularly frequency and amplitude, are entrained (reset) by the anticanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ab71f29335a224c6199f13f26ed7b4
http://link.springer.com/article/10.1038/s41598-020-58579-2
http://link.springer.com/article/10.1038/s41598-020-58579-2