Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Devaraja Rajasekaran"'
Autor:
Tyler Sniegowski, Devaraja Rajasekaran, Souad R. Sennoune, Sukumaran Sunitha, Fang Chen, Mohamed Fokar, Sudhir Kshirsagar, P. Hemachandra Reddy, Ksenija Korac, Mosharaf Mahmud Syed, Tanima Sharker, Vadivel Ganapathy, Yangzom D. Bhutia
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) cells have a great demand for nutrients in the form of sugars, amino acids, and lipids. Particularly, amino acids are critical for cancer growth and, as intermediates, connect glucose, lipid and nucleo
Externí odkaz:
https://doaj.org/article/8da0a1c1200e43b09d36b442c5a114e9
Autor:
Yangzom D. Bhutia, Jiro Ogura, Paul J. Grippo, Carolina Torres, Toshihiro Sato, Mitchell Wachtel, Sabarish Ramachandran, Ellappan Babu, Sathish Sivaprakasam, Devaraja Rajasekaran, Bradley Schniers, Nhu On, Logan Smoot, Muthusamy Thangaraju, Jaya P. Gnana-Prakasam, Vadivel Ganapathy
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 15, Iss 2, Pp 237-251 (2020)
Based on the evidence that hemochromatosis, an iron-overload disease, drives hepatocellular carcinoma, we hypothesized that chronic exposure to excess iron, either due to genetic or environmental causes, predisposes an individual to cancer. Using pan
Externí odkaz:
https://doaj.org/article/fa207eb435da45528dce5dad9ee9ba3b
Autor:
Prasanna K. Santhekadur, Maaged Akiel, Luni Emdad, Rachel Gredler, Jyoti Srivastava, Devaraja Rajasekaran, Chadia L. Robertson, Nitai D. Mukhopadhyay, Paul B. Fisher, Devanand Sarkar
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 353-361 (2014)
Staphylococcal nuclease domain containing-1 (SND1) is overexpressed in human hepatocellular carcinoma (HCC) patients and promotes tumorigenesis by human HCC cells. We now document that SND1 increases angiotensin II type 1 receptor (AT1R) levels by in
Externí odkaz:
https://doaj.org/article/28c938fd7fad4148a325f713857b46f5
Autor:
Devanand Sarkar, Arun J. Sanyal, Paul B. Fisher, Jolene J. Windle, Mark A. Subler, Chadia L. Robertson, Maaged A. Akiel, Ayesha Siddiq, Xue-Ning Shen, Rachel G. Mendoza, Devaraja Rajasekaran, Nidhi Jariwala
Analysis of MGLL and AT1R levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2901d521d7791cb4674494b9f4da779a
https://doi.org/10.1158/0008-5472.22413893
https://doi.org/10.1158/0008-5472.22413893
Autor:
Devanand Sarkar, Xiang-Yang Wang, Paul B. Fisher, Shah Giashuddin, Yidong Chen, Hung-I Harry Chen, Zhao Lai, Dawn K. Garcia, Jolene Windle, Mark A. Subler, Fang Yuan, Nidhi Jariwala, Chadia L. Robertson, Rachel G. Mendoza, Devaraja Rajasekaran, Xia Li, Chunqing Guo, Maaged Akiel
Fig. S1 describes creation of Igfbp7-/- mice. Fig. S2 shows histology of different organs of Igfbp7 / and -/- mice. Fig. S3 shows images of senescent hepatocytes. Fig. S4 shows quantification of all Western blots. Fig. S5 shows histology and GS stain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f18bb4db21d07318f308a16d93c24e8
https://doi.org/10.1158/0008-5472.22415384
https://doi.org/10.1158/0008-5472.22415384
Autor:
Devanand Sarkar, Arun J. Sanyal, Paul B. Fisher, Jolene J. Windle, Mark A. Subler, Chadia L. Robertson, Maaged A. Akiel, Ayesha Siddiq, Xue-Ning Shen, Rachel G. Mendoza, Devaraja Rajasekaran, Nidhi Jariwala
File contains text of supplementary methods and figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c107943ee886d5b6eff1a94ebc2216
https://doi.org/10.1158/0008-5472.22413890.v1
https://doi.org/10.1158/0008-5472.22413890.v1
Autor:
Devanand Sarkar, Arun J. Sanyal, Paul B. Fisher, Jolene J. Windle, Mark A. Subler, Chadia L. Robertson, Maaged A. Akiel, Ayesha Siddiq, Xue-Ning Shen, Rachel G. Mendoza, Devaraja Rajasekaran, Nidhi Jariwala
SND1, a subunit of the miRNA regulatory complex RISC, has been implicated as an oncogene in hepatocellular carcinoma (HCC). In this study, we show that hepatocyte-specific SND1 transgenic mice (Alb/SND1 mice) develop spontaneous HCC with partial pene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec75ace9e5ecc59c4830a0ad1448672f
https://doi.org/10.1158/0008-5472.c.6508844.v1
https://doi.org/10.1158/0008-5472.c.6508844.v1
Autor:
Devanand Sarkar, Paul B. Fisher, Jolene J. Windle, Mark A. Subler, Shobha Ghosh, Xiang-Yang Wang, Shah Giashuddin, Chunqing Guo, Xue-Ning Shen, Maaged Akiel, Devaraja Rajasekaran, Luni Emdad, Rachel Gredler, Ayesha Siddiq, Jyoti Srivastava, Chadia L. Robertson
Legends for Supplementary Tables S1-S7 and Supplementary Figures S1-S5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e465009c27f09bf0f0e07bd168e6b2
https://doi.org/10.1158/0008-5472.22406415
https://doi.org/10.1158/0008-5472.22406415
Autor:
Devanand Sarkar, Paul B. Fisher, Jolene J. Windle, Mark A. Subler, Shobha Ghosh, Xiang-Yang Wang, Shah Giashuddin, Chunqing Guo, Xue-Ning Shen, Maaged Akiel, Devaraja Rajasekaran, Luni Emdad, Rachel Gredler, Ayesha Siddiq, Jyoti Srivastava, Chadia L. Robertson
Differential count of bone marrow cells (% of total cell count).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fc43cb645f7d5354ac240c455938bd
https://doi.org/10.1158/0008-5472.22406406.v1
https://doi.org/10.1158/0008-5472.22406406.v1
Autor:
Devanand Sarkar, Paul B. Fisher, Jolene J. Windle, Mark A. Subler, Shobha Ghosh, Xiang-Yang Wang, Shah Giashuddin, Chunqing Guo, Xue-Ning Shen, Maaged Akiel, Devaraja Rajasekaran, Luni Emdad, Rachel Gredler, Ayesha Siddiq, Jyoti Srivastava, Chadia L. Robertson
Generation of AEG-1KO mouse (S1); Analysis of spleen cells of adult WT and AEG-1KO mice (S2); F4/80 staining for macrophages in spleen sections of aged (16 m) WT and AEG-1KO mouse. Magnification 400X (S3); Graphical representation of quantification o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0626f588edbd22ecb006fbb65edaaefc
https://doi.org/10.1158/0008-5472.22406412
https://doi.org/10.1158/0008-5472.22406412