Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Devanshi Jain"'
Autor:
Rong Liu, Seth D. Kasowitz, David Homolka, N. Adrian Leu, Jordan T. Shaked, Gordon Ruthel, Devanshi Jain, Huijuan Lin, Scott Keeney, Mengcheng Luo, Ramesh S. Pillai, P. Jeremy Wang
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110110- (2021)
Summary: Mechanisms driving the prolonged meiotic prophase I in mammals are poorly understood. RNA helicase YTHDC2 is critical for mitosis to meiosis transition. However, YTHDC2 is highly expressed in pachytene cells. Here we identify an essential ro
Externí odkaz:
https://doaj.org/article/5e6e1c32c1214f81825e5a7b07b206dd
Publikováno v:
PLoS Genetics, Vol 17, Iss 2, p e1009265 (2021)
Piwi-interacting RNAs (piRNAs) play critical roles in protecting germline genome integrity and promoting normal spermiogenic differentiation. In mammals, there are two populations of piRNAs: pre-pachytene and pachytene. Transposon-rich pre-pachytene
Externí odkaz:
https://doaj.org/article/3652cb17792e47f59a1fba3e30233bcf
Publikováno v:
eLife, Vol 7 (2018)
Chromosome replication and transcription occur within a complex nuclear milieu whose functional subdomains are beginning to be mapped out. Here we delineate distinct domains of the fission yeast nuclear envelope (NE), focusing on regions enriched for
Externí odkaz:
https://doaj.org/article/65323f0785b04f658f1ac4668f115c33
Autor:
Devanshi Jain, M Rhyan Puno, Cem Meydan, Nathalie Lailler, Christopher E Mason, Christopher D Lima, Kathryn V Anderson, Scott Keeney
Publikováno v:
eLife, Vol 7 (2018)
Mechanisms regulating mammalian meiotic progression are poorly understood. Here we identify mouse YTHDC2 as a critical component. A screen yielded a sterile mutant, ‘ketu’, caused by a Ythdc2 missense mutation. Mutant germ cells enter meiosis but
Externí odkaz:
https://doaj.org/article/08ec398323f14159913426dc55b9377a
Autor:
Devanshi Jain, Cem Meydan, Julian Lange, Corentin Claeys Bouuaert, Nathalie Lailler, Christopher E Mason, Kathryn V Anderson, Scott Keeney
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006964 (2017)
Transcriptional silencing by heritable cytosine-5 methylation is an ancient strategy to repress transposable elements. It was previously thought that mammals possess four DNA methyltransferase paralogs-Dnmt1, Dnmt3a, Dnmt3b and Dnmt3l-that establish
Externí odkaz:
https://doaj.org/article/cde3a330bdbf428189a795ce541b1643
Autor:
Fiona Pryde, Devanshi Jain, Alastair Kerr, Rebecca Curley, Francesca Romana Mariotti, Maria Vogelauer
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5882 (2009)
Replication origins fire at different times during S-phase. Such timing is determined by the chromosomal context, which includes the activity of nearby genes, telomeric position effects and chromatin structure, such as the acetylation state of the su
Externí odkaz:
https://doaj.org/article/fe4856f4fe4e4e4ea683ea15fa68a3fd
Publikováno v:
Expert Opinion on Drug Safety. :1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fe8f3226865fb1320afbf14408d8b3a
https://doi.org/10.1080/14740338.2023.2189698
https://doi.org/10.1080/14740338.2023.2189698
Autor:
Yuhki Saito, Ben R. Hawley, M. Rhyan Puno, Shreya N. Sarathy, Christopher D. Lima, Samie R. Jaffrey, Robert B. Darnell, Scott Keeney, Devanshi Jain
Publikováno v:
Genes & Development. 36:180-194
Mechanisms regulating meiotic progression in mammals are poorly understood. The N6-methyladenosine (m6A) reader and 3′ → 5′ RNA helicase YTHDC2 switches cells from mitotic to meiotic gene expression programs and is essential for meiotic entry,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa0a85f8cc77c9b57f29c1d63f9b34bd
https://doi.org/10.1101/gad.349190.121
https://doi.org/10.1101/gad.349190.121
India is a large and growing market for the consumption of OTT content, there is very little research done to explain the factors that affect the consumers when they choose which platform to subscribe to. This study was conducted to understand the ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950b4990dec62106f4c8908a593a8b60
Autor:
Yuhki, Saito, Ben R, Hawley, M Rhyan, Puno, Shreya N, Sarathy, Christopher D, Lima, Samie R, Jaffrey, Robert B, Darnell, Scott, Keeney, Devanshi, Jain
Publikováno v:
Genesdevelopment. 36(3-4)
Mechanisms regulating meiotic progression in mammals are poorly understood. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5227ee7d460bd9c2bbbc54bd9af7ef34
https://pubmed.ncbi.nlm.nih.gov/35058317
https://pubmed.ncbi.nlm.nih.gov/35058317