Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Devanjali, Dutta"'
Autor:
Devanjali Dutta, L. Francisco Lorenzo-Martín, François Rivest, Nicolas Broguiere, Lucie Tillard, Simone Ragusa, Nathalie Brandenberg, Sylke Höhnel, Damien Saugy, Sylvie Rusakiewicz, Krisztian Homicsko, George Coukos, Matthias P. Lutolf
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-7 (2024)
Abstract Immunotherapy has emerged as a new standard of care for certain cancer patients with specific cellular and molecular makeups. However, there is still an unmet need for ex vivo models able to readily assess the effectiveness of immunotherapeu
Externí odkaz:
https://doaj.org/article/500b8010d8694a5e80a921b03b5440e1
Autor:
Annie S. P. Yang, Devanjali Dutta, Kai Kretzschmar, Delilah Hendriks, Jens Puschhof, Huili Hu, Kim E. Boonekamp, Youri van Waardenburg, Susana M. Chuva de Sousa Lopes, Geert-Jan van Gemert, Johannes H. W. de Wilt, Teun Bousema, Hans Clevers, Robert W. Sauerwein
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Plasmodium falciparum (Pf) parasite development in liver represents the initial step of the life-cycle in the human host after a Pf-infected mosquito bite. While an attractive stage for life-cycle interruption, understanding of parasite-hepa
Externí odkaz:
https://doaj.org/article/5c88670c6cde4830afc419a55a86cad4
Autor:
Flavio Bonanini, Dorota Kurek, Sara Previdi, Arnaud Nicolas, Delilah Hendriks, Sander de Ruiter, Marine Meyer, Maria Clapés Cabrer, Roelof Dinkelberg, Silvia Bonilla García, Bart Kramer, Thomas Olivier, Huili Hu, Carmen López-Iglesias, Frederik Schavemaker, Erik Walinga, Devanjali Dutta, Karla Queiroz, Karel Domansky, Bob Ronden, Jos Joore, Henriette L. Lanz, Peter J. Peters, Sebastiaan J. Trietsch, Hans Clevers, Paul Vulto
Publikováno v:
Angiogenesis
Angiogenesis, 25(4), 455-470. Springer, Cham
Angiogenesis, 25(4), 455-470. Springer Netherlands
Angiogenesis, 25(4), 455-470. Springer, Cham
Angiogenesis, 25(4), 455-470. Springer Netherlands
With recent progress in modeling liver organogenesis and regeneration, the lack of vasculature is becoming the bottleneck in progressing our ability to model human hepatic tissues in vitro. Here, we introduce a platform for routine grafting of liver
Autor:
Inha Heo, Hans Clevers, Ninouk Akkerman, Adriana Martinez-Silgado, Aurelia Saftien, Cayetano Pleguezuelos-Manzano, Charelle Boot, Joep Beumer, Amy de Waal, Devanjali Dutta, Jens Puschhof
Publikováno v:
Nature Protocols. 16(10):4633-4649
Adult-stem-cell-derived organoids model human epithelial tissues ex vivo, which enables the study of host–microbe interactions with great experimental control. This protocol comprises methods to coculture organoids with microbes, particularly focus
Autor:
Devanjali Dutta, Adam J. Dobson, Philip L. Houtz, Christine Gläßer, Jonathan Revah, Jerome Korzelius, Parthive H. Patel, Bruce A. Edgar, Nicolas Buchon
Publikováno v:
Cell Reports, Vol 12, Iss 2, Pp 346-358 (2015)
Deciphering contributions of specific cell types to organ function is experimentally challenging. The Drosophila midgut is a dynamic organ with five morphologically and functionally distinct regions (R1–R5), each composed of multipotent intestinal
Externí odkaz:
https://doaj.org/article/3c3866e48896413cb1b78ec8f8334b2d
Autor:
Norman Zielke, Jerome Korzelius, Monique van Straaten, Katharina Bender, Gregor F.P. Schuhknecht, Devanjali Dutta, Jinyi Xiang, Bruce A. Edgar
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 588-598 (2014)
Summary: One promising approach for in vivo studies of cell proliferation is the FUCCI system (fluorescent ubiquitination-based cell cycle indicator). Here, we report the development of a Drosophila-specific FUCCI system (Fly-FUCCI) that allows one t
Externí odkaz:
https://doaj.org/article/10f4c6471766437b83cc97a413d40b5d
Autor:
Ana C.F. Bolhaqueiro, Nizar Hami, Devanjali Dutta, Nobuo Sasaki, Onno Kranenburg, Judith Vivié, Marc van de Wetering, Peter M. Lansdorp, Robert G.J. Vries, Alexander van Oudenaarden, Geert J. P. L. Kops, Hans Clevers, Diana C.J. Spierings, Hugo J. Snippert, Ingrid Verlaan-Klink, Bas Ponsioen, Emre Kucukkose, Richard H. van Jaarsveld, Bjorn Bakker, Sjoerd J Klaasen, Floris Foijer, Sylvia F. Boj
Publikováno v:
Nature Genetics, 51(5), 824-834. Nature Publishing Group
Nature Genetics, 51(5), 824. Nature Publishing Group
Nature Genetics
Nature Genetics, 51(5), 824. Nature Publishing Group
Nature Genetics
Chromosome segregation errors cause aneuploidy and genomic heterogeneity, which are hallmarks of cancer in humans. A persistent high frequency of these errors (chromosomal instability (CIN)) is predicted to profoundly impact tumor evolution and thera
Autor:
Simone Ragusa, Krisztian Homicsko, Francois Rivest, Devanjali Dutta, Nicolas Broguiere, Nathalie Brandenberg, Damien Saugy, Sylke Hohnel, Matthias P. Lutolf, Sylvie Rusakiewicz, L. Francisco Lorenzo-Martín, Lucie Tillard, George Coukos
Immunotherapy has shown promise as an approach to fight cancer by harnessing the immune system. However, due to the lack of biomarkers to guide treatment regimens and predict response rates, there is an unmet need for more robust ex vivo and in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6904e0ba640f51373e3011ba8934e2cd
https://doi.org/10.1101/2021.03.30.437679
https://doi.org/10.1101/2021.03.30.437679
Autor:
Jens, Puschhof, Cayetano, Pleguezuelos-Manzano, Adriana, Martinez-Silgado, Ninouk, Akkerman, Aurelia, Saftien, Charelle, Boot, Amy, de Waal, Joep, Beumer, Devanjali, Dutta, Inha, Heo, Hans, Clevers
Publikováno v:
Nature protocols. 16(10)
Adult-stem-cell-derived organoids model human epithelial tissues ex vivo, which enables the study of host-microbe interactions with great experimental control. This protocol comprises methods to coculture organoids with microbes, particularly focusin
Autor:
Kim E Boonekamp, Antoni P. A. Hendrickx, Benedetta Artegiani, Deborah A. Schaefer, Michael W. Riggs, Inha Heo, Devanjali Dutta, Robert J L Willems, Nino Iakobachvili, Roberta M. O'Connor, Gregory D. Bowden, Hans Clevers, Norman Sachs, Peter J. Peters
Publikováno v:
Nature Microbiology, 3(7), 814-823. Nature Publishing Group
Nature Microbiology, 3(7), 814. Nature Publishing Group
Nature Microbiology
Nature Microbiology, 3(7), 814. Nature Publishing Group
Nature Microbiology
Stem-cell-derived organoids recapitulate in vivo physiology of their original tissues, representing valuable systems to model medical disorders such as infectious diseases. Cryptosporidium, a protozoan parasite, is a leading cause of diarrhoea and a