Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Dev Samarasinghe"'
Publikováno v:
In Hepatology 2001 34(4) Part 2:A456-A456
Publikováno v:
In Hepatology 2001 34(4) Part 2:A360-A360
Autor:
Vi Nguyen, Kathy Jackson, Dev Samarasinghe, A. Glass, Miriam T. Levy, Susan Holdaway, Astrid-Jane Greenup, Ushmi Chatterjee, Stephen Locarnini, Scott Davison, Pok Kern Tan
Publikováno v:
Journal of Hepatology. 61:502-507
Background & Aims Perinatal transmission of hepatitis B virus still occurs despite immunoprophylaxis in approximately 9% of children from highly viraemic mothers. Antiviral therapy in this setting has been suggested, however with limited evidence to
Autor:
Geoffrey C. Farrell, Rita Lin, Jacob George, Mahbub Khan, Martin Weltman, Dev Samarasinghe, Christopher Liddle, Karen Byth, James G. Kench, Evelyn Crewe, Shirley A Coverdale
Publikováno v:
American Journal of Gastroenterology. 99:636-644
Fibrotic severity, biochemical indices of poor liver function, and sporadic transmission are independent predictors of liver complications among people with chronic hepatitis C. After accounting for these factors, we tested whether interferon treatme
Autor:
Karen Byth, Dev Samarasinghe, Geoffrey C. Farrell, Rita Lin, James G. Kench, Christopher Liddle, Mahbub Khan, Jacob George, Evelyn Crewe, Shirley A Coverdale
Publikováno v:
American Journal of Gastroenterology. 98:1384-1390
We tested whether fibrotic progression in chronic hepatitis C could be predicted by liver tests, antipyrine clearance, or platelet count.In 58 patients (6 untreated, 52 interferon-treated), a second liver biopsy was taken median 4.5 yr after first hi
Autor:
Rita Lin, Linda Frost, Adamandia D. Kriketos, Geoffrey C. Farrell, Christopher Liddle, Shivakumar Chitturi, Jacob George, Dev Samarasinghe
Publikováno v:
Hepatology. 36:403-409
Nonalcoholic steatohepatitis (NASH) is a disorder characterized by hepatic steatosis, inflammation, and fibrosis. Leptin is an adipocyte-derived antiobesity hormone that in rodents prevents "lipotoxicity" by limiting triglyceride accumulation and als
Autor:
Dev Samarasinghe, Christopher Liddle, Jacob George, Shivakumar Chitturi, Martin Weltman, David McDonald, Rita Lin, Geoffrey C. Farrell, Shehan Abeygunasekera
Publikováno v:
Hepatology. 36:142-149
There is conflicting evidence regarding inheritance of hemochromatosis gene (HFE) mutations and influence of hepatic iron deposition as cofactors for development of fibrosis in patients with nonalcoholic steatohepatitis (NASH). We studied hepatic iro
Autor:
Jason M. Hui, Geoffrey C. Farrell, Rita Lin, Christopher Liddle, Dev Samarasinghe, Jacob George, Evelyn Crewe
Publikováno v:
The American Journal of Gastroenterology. 97:1003-1009
In chronic hepatitis B patients treated with lamivudine, the incidence of drug resistance increases with the duration of therapy. The effect of drug resistance on hepatic synthetic function is not well defined. The aim of the present study was to ass
Autor:
Jason M. Hui, Dev Samarasinghe, Rita Lin, Jane Holmes-Walker, Martin Weltman, Shehan Abeygunasekera, Christopher Liddle, Shivakumar Chitturi, Jacob George, Rooshdiya Z. Karim, Caroline L.-S. Fung, Geoffrey C. Farrell
Publikováno v:
Hepatology. 35:373-379
Nonalcoholic steatohepatitis (NASH) is often linked with disorders that are clearly associated with insulin resistance (IR): obesity, type 2 diabetes mellitus, and hypertriglyceridemia. We tested the hypotheses that (1) IR is an essential requirement
Autor:
Geoffrey C. Farrell, Dev Samarasinghe
Publikováno v:
Hepatology. 24:1230-1237
The role of individual cell types in hepatic hypoxia-reoxygenation (reperfusion) injury has not been completely defined. We therefore examined the effects of hypoxia and hypoxia-reoxygenation on the viability of rat hepatocytes, Kupffer cells, and si