Zobrazeno 1 - 10
of 567
pro vyhledávání: '"Deubiquitinating Enzyme CYLD"'
Autor:
Ana Claudia Rolim Branco, Bruna Mendes Almeida, Clóvis Antônio Lopes Pinto, Célia Antônia Xavier de Moraes Alves
Publikováno v:
Surgical & Cosmetic Dermatology, Vol 16 (2024)
Cylindroma is a rare benign neoplasm of probable origin in the eccrine sweat glands and is characterized by papular and nodular, painless, slow-growing lesions, generally located on the head, neck and scalp. When multiple, they can be part of heredit
Externí odkaz:
https://doaj.org/article/7bb172e85958489a8618b106051cc6eb
Publikováno v:
Biochemistry (Moscow). 87:957-964
Toll-like receptor 4 (TLR4) is a key pattern recognition receptor that can be activated by bacterial lipopolysaccharide to elicit inflammatory response. Proper activation of TLR4 is critical for the host defense against microbial infections. Since ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2279372fff02f208c009329c33d3af0
https://doi.org/10.1134/s0006297922090085
https://doi.org/10.1134/s0006297922090085
Autor:
Xuewen Xiao, Tianyan Xu, Hui Liu, Xixi Liu, Xinxin Liao, Yafang Zhou, Lu Zhou, Xin Wang, Yuan Zhu, Qijie Yang, Xiaoli Hao, Yingzi Liu, Hong Jiang, Jifeng Guo, Junling Wang, Beisha Tang, Jinchen Li, Lu Shen, Bin Jiao
Publikováno v:
Annals of Clinical and Translational Neurology. 9:1596-1601
CYLD was a novel causative gene for frontotemporal dementia (FTD) and amyotrophic lateral sclerosis. Given the clinical and pathological overlap of FTD and Alzheimer's disease (AD), it is necessary to screen CYLD in AD patients and FTD patients in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038e87c2dd3557c16e666e8ce8ca947f
https://doi.org/10.1002/acn3.51655
https://doi.org/10.1002/acn3.51655
Autor:
Zhengxin Chen, Shuai Wang, Hai-Lin Li, Hui Luo, Xiaoting Wu, Jiacheng Lu, Hong-Wei Wang, Yuanyuan Chen, Dan Chen, Wen-Ting Wu, Shuyu Zhang, Qiongqiong He, Daru Lu, Ning Liu, Yongping You, Wei Wu, Huibo Wang
Publikováno v:
Mol Ther
Proneural (PN) to mesenchymal (MES) transition (PMT) is a crucial phenotypic shift in glioblastoma stem cells (GSCs). However, the mechanisms driving this process remain poorly understood. Here, we report that Fos-like antigen 1 (FOSL1), a component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61d9bac10944ef64a130372f349775f
https://doi.org/10.1016/j.ymthe.2021.10.028
https://doi.org/10.1016/j.ymthe.2021.10.028
Akademický článek
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Publikováno v:
Nature Cell Biology. 23:978-991
The extracellular-signal-regulated kinases ERK1 and ERK2 (hereafter ERK1/2) represent the foremost mitogenic pathway in mammalian cells, and their dysregulation drives tumorigenesis and confers therapeutic resistance. ERK1/2 are known to be activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a2b516bddedc06df06c5f8b5c60047
https://doi.org/10.1038/s41556-021-00732-8
https://doi.org/10.1038/s41556-021-00732-8
Autor:
Lirong Tan, Xueting Yu, Xiaofan Yu, Jian Tong, Ruixin Yao, Tao Chen, Jianxiang Li, Nan Ouyang, Xiyuan Cao, Jin Wang, Rui Chen, Beibei Jia
Publikováno v:
International Journal of Biological Sciences
Lung cancer is one of the most common types of carcinoma worldwide. Cigarette smoking is considered the leading cause of lung cancer. Aberrant expression of several YT521-B homology (YTH) family proteins has been reported to be closely associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee852ac89d32461001e31db083bc5100
http://europepmc.org/articles/PMC8315025
http://europepmc.org/articles/PMC8315025
Publikováno v:
Chemical biologydrug designREFERENCES. 101(1)
Osteosarcoma is a common human malignancy with a high mortality rate worldwide. Recent studies have been focused on understanding the involvement of microRNA (miRNAs) in the pathogenesis of osteosarcoma. Therefore, the present study aimed to measure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d3d46c4e055f440fc2fa2343b3ec039
https://pubmed.ncbi.nlm.nih.gov/36098711
https://pubmed.ncbi.nlm.nih.gov/36098711
Autor:
Han Du, Zixin Huang, Xin Zhou, Xielan Kuang, Chongde Long, Han Tang, Jingshu Zeng, Hao Huang, Huijun Liu, Binbin Zhu, Licheng Fu, Ke Hu, ShuiBin Lin, Hua Wang, Qingjiong Zhang, Jianhua Yan, Huangxuan Shen
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 36(10)
Oxidative stress-induced damage to and dysfunction of retinal pigment epithelium (RPE) cells are important pathogenetic factors of age-related macular degeneration (AMD); however, the underlying molecular mechanism is not fully understood. Long nonco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e8d72c473aade2cd5a59ad7c2772e4
https://pubmed.ncbi.nlm.nih.gov/36165267
https://pubmed.ncbi.nlm.nih.gov/36165267
Publikováno v:
Chemico-biological interactions. 368
Ferroptosis is an iron-dependent cell death and contributes to doxorubicin-induced cardiotoxicity, but the mechanisms behind intracellular iron overload in cardiomyocyte after administration of doxorubicin remain largely unknown. Ferritinophagy is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a165e45c8c73d43eb559f1ceb1454fb
https://pubmed.ncbi.nlm.nih.gov/36195186
https://pubmed.ncbi.nlm.nih.gov/36195186