Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Detlev Riesner"'
Publikováno v:
Viruses, Vol 16, Iss 3, p 360 (2024)
Theodor (“Ted”) Otto Diener (* 28 February 1921 in Zürich, Switzerland; † 28 March 2023 in Beltsville, MD, USA) pioneered research on viroids while working at the Plant Virology Laboratory, Agricultural Research Service, USDA, in Beltsville. H
Externí odkaz:
https://doaj.org/article/525f4aa56a7d419b8342b9ce39947de4
Autor:
Marlene Pils, Alexandra Dybala, Fabian Rehn, Lara Blömeke, Tuyen Bujnicki, Victoria Kraemer-Schulien, Wolfgang Hoyer, Detlev Riesner, Dieter Willbold, Oliver Bannach
Publikováno v:
Diagnostics, Vol 13, Iss 10, p 1702 (2023)
Protein misfolding and aggregation are pathological hallmarks of various neurodegenerative diseases. In Alzheimer’s disease (AD), soluble and toxic amyloid-β (Aβ) oligomers are biomarker candidates for diagnostics and drug development. However, a
Externí odkaz:
https://doaj.org/article/a2e5358ebe9c4be7984a66f0da50eda1
Publikováno v:
Molecules, Vol 25, Iss 13, p 3100 (2020)
Deoxyribozymes (DNAzymes) with RNA hydrolysis activity have a tremendous potential as gene suppression agents for therapeutic applications. The most extensively studied representative is the 10-23 DNAzyme consisting of a catalytic loop and two substr
Externí odkaz:
https://doaj.org/article/39ce5b52238e488e9f5fc4dab73e5511
Autor:
Lars Luers, Oliver Bannach, Jan Stöhr, Michael Marius Wördehoff, Martin Wolff, Luitgard Nagel-Steger, Detlev Riesner, Dieter Willbold, Eva Birkmann
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72623 (2013)
Prion diseases are transmissible spongiform encephalopathies in humans and animals, including scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle, chronic wasting disease (CWD) in deer, and Creutzfeldt-Jakob disease (CJD) in humans. Th
Externí odkaz:
https://doaj.org/article/90264ae12c074bb1b9292aa470c403e4
Autor:
Oliver Bannach, Eva Birkmann, Elke Reinartz, Karl-Erich Jaeger, Jan P M Langeveld, Robert G Rohwer, Luisa Gregori, Linda A Terry, Dieter Willbold, Detlev Riesner
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36620 (2012)
Prion diseases are transmissible neurodegenerative diseases affecting humans and animals. The agent of the disease is the prion consisting mainly, if not solely, of a misfolded and aggregated isoform of the host-encoded prion protein (PrP). Transmiss
Externí odkaz:
https://doaj.org/article/6a1aa95a6b26452eb9c09990d83524e1
Autor:
Giannantonio Panza, Lars Luers, Jan Stöhr, Luitgard Nagel-Steger, Jürgen Weiss, Detlev Riesner, Dieter Willbold, Eva Birkmann
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14283 (2010)
Prion diseases like Creutzfeldt-Jakob disease in humans, Scrapie in sheep or bovine spongiform encephalopathy are fatal neurodegenerative diseases, which can be of sporadic, genetic, or infectious origin. Prion diseases are transmissible between diff
Externí odkaz:
https://doaj.org/article/b2431ef0d6374eac9693093cffcd8333
Autor:
Jan Borggräfe, Julian Victor, Hannah Rosenbach, Aldino Viegas, Christoph G. W. Gertzen, Christine Wuebben, Helena Kovacs, Mohanraj Gopalswamy, Detlev Riesner, Gerhard Steger, Olav Schiemann, Holger Gohlke, Ingrid Span, Manuel Etzkorn
Publikováno v:
Nature 601, 144-149 (2022). doi:10.1038/s41586-021-04225-4
The 10–23 DNAzyme is one of the most prominent catalytically active DNA sequences1,2. Its ability to cleave a wide range of RNA targets with high selectivity entails a substantial therapeutic and biotechnological potential2. However, the high expec
Autor:
Detlev Riesner, Hans Süssmuth
Publikováno v:
Neues aus Wissenschaft und Lehre ISBN: 9783110720037
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8511fa2dae30583ea5d827652ebd5e9
https://doi.org/10.1515/9783110720037-067
https://doi.org/10.1515/9783110720037-067
Publikováno v:
European Biophysics Journal. 47:333-343
Sequence specific cleavage of RNA can be achieved by hammerhead ribozymes as well as DNAzymes. They comprise a catalytic core sequence flanked by regions that form double strands with complementary RNA. While different types of ribozymes have been di
Autor:
Detlev Riesner, Gerhard Steger
Publikováno v:
Nucleic Acids Research
Viroids were described 47 years ago as the smallest RNA molecules capable of infecting plants and autonomously self-replicating without an encoded protein. Work on viroids initiated the development of a number of innovative methods. Novel chromatogra