Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Detlef Kozian"'
Publikováno v:
Journal of Urology. 197
Publikováno v:
Drug Development Research. 74:440-449
Preclinical Research Platelets are small anucleated cells produced by bone marrow megakaryocytes that circulate in the blood as sentinels of vascular integrity. They play a pivotal role in the regulation of vascular homeostasis through adhesion to th
Autor:
Bernhard O. Böhm, Sandrine Mace, Matthias Schäfer, Detlef Kozian, Bernhard J. Winkelmann, Andreas Evers, Jean-François Deleuze, Sanofi-Aventis Deutschland, Winfried März
Publikováno v:
Journal of Diabetes & Metabolism.
Aim: S1PR2 is one of five known sphingosine-1-phosphate receptors and has recently been discussed to be implicated in the development or progression of diabetes. Our aim was to identify S1PR2 polymorphisms in the coding region of the human S1PR2 gene
Autor:
Detlef Kozian, Jean-François Deleuze, Sandrine Mace, Martin Lorenz, Winfried März, Emmanuelle Cousin
Publikováno v:
Thrombosis and haemostasis. 103(5)
SummaryThe thrombin-activatable fibrinolysis inhibitor (TAFI) is a key mediator in the regulation of endogenous fibrinolysis, down-regulating clot lysis by degrading the C-terminal lysine residues from fibrin, which are important for binding and acti
Publikováno v:
The Journal of biological chemistry. 281(46)
The highly conserved protein eIF5A found in Archaea and all eukaryotes uniquely contains the posttranslationally formed amino acid hypusine. Despite being essential the functions of this protein and its modification remain unclear. To gain more insig
Autor:
Dominique Meyer, Valérie Proulle, Almut Nitsche, Detlef Kozian, Danièle Kerbiriou-Nabias, Matthias Herrmann, Marie-Carmen Martinez, Beatrice Schumann, Marie Galitzine, Jean-Marie Freyssinet
Publikováno v:
BMC Genomics, Vol 6, Iss 1, p 146 (2005)
BMC Genomics
BMC Genomics, BioMed Central, 2005, 6, pp.146. ⟨10.1186/1471-2164-6-146⟩
BMC Genomics
BMC Genomics, BioMed Central, 2005, 6, pp.146. ⟨10.1186/1471-2164-6-146⟩
BackgroundIn contrast to other agents able to induce apoptosis of cultured cells, Ca2+ionophore A23187 was shown to elicit direct activation of intracellular signal(s). The phenotype of the cells derived from patients having the hemorrhagic disease S
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 4(3)
Heparin and warfarin are the most widely used anticoagulants for the prophylaxis and treatment of thrombus-based diseases. These anticoagulants, however, have well-known clinical limitations, such as a slow onset of action and a narrow therapeutic wi
Publikováno v:
Journal of cell science. 108
Cadherins are a gene family encoding calcium-dependent cell adhesion proteins which are thought to act in the establishment and maintenance of tissue organization. M-cadherin, one member of the family, has been found in myogenic cells of somitic orig