Zobrazeno 1 - 10
of 410
pro vyhledávání: '"Detlef K, Bartsch"'
Autor:
Max B. Albers, Martina Sevcik, Dominik Wiese, Jerena Manoharan, Anja Rinke, Moritz Jesinghaus, Detlef K. Bartsch
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Functioning pancreatic neuroendocrine neoplasms other than insulinomas and gastrinomas (rf-pNENs) are exceptionally rare tumours. Thus, their characteristics and long-term prognosis have not been well defined. This article aims to present da
Externí odkaz:
https://doaj.org/article/cdc97dfde5004dd783adf949c2640373
Autor:
Sebastian Foersch, Maxime Schmitt, Anne‐Sophie Litmeyer, Markus Tschurtschenthaler, Thomas Gress, Detlef K Bartsch, Nicole Pfarr, Katja Steiger, Carsten Denkert, Moritz Jesinghaus
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 5, Pp n/a-n/a (2024)
Abstract Antibody–drug conjugates (ADCs) directed to trophoblast cell surface antigen 2 (TROP2) have gained approval as a therapeutic option for advanced triple‐negative breast cancer, and TROP2 expression has been linked to unfavourable outcomes
Externí odkaz:
https://doaj.org/article/8a36804c34c64ace9a0a2bc6238a569b
Autor:
Anne‐Sophie Litmeyer, Björn Konukiewitz, Atsuko Kasajima, Sebastian Foersch, Felix Schicktanz, Maxime Schmitt, Franziska Kellers, Albert Grass, Paul Jank, Bettina Lehman, Thomas M Gress, Anja Rinke, Detlef K Bartsch, Carsten Denkert, Wilko Weichert, Günter Klöppel, Moritz Jesinghaus
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 6, Pp 498-509 (2023)
Abstract Complementary to synaptophysin and chromogranin A, insulinoma‐associated protein 1 (INSM1) has emerged as a sensitive marker for the diagnosis of neuroendocrine neoplasms. Since there are no comparative data regarding INSM1 expression in c
Externí odkaz:
https://doaj.org/article/341b6cb122f243fc92b1c5ab08d08acc
Autor:
Maren Stark, Marina Nicolai, Marina Tatura, Corinna U. Keber, Andreas Kaufmann, Ho‐Ryun Chung, Emily P. Slater, Christopher Heeschen, Rita T. Lawlor, Aldo Scarpa, Detlef K. Bartsch, Thomas M. Gress, Stefan Bauer, Malte Buchholz
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8542-8556 (2023)
Abstract Background Toll‐like receptors (TLRs) are gaining attention for their potential to influence tumor biology both on the level of the tumor cells as well as on the level of the surrounding inflammatory stroma. Previous studies resulted in pa
Externí odkaz:
https://doaj.org/article/d14b8a3d788f4c6caf9c5dd955d6c74f
Autor:
Felix O. Hofmann, Rainer C. Miksch, Maximilian Weniger, Tobias Keck, Matthias Anthuber, Helmut Witzigmann, Natascha C. Nuessler, Christoph Reissfelder, Jörg Köninger, Michael Ghadimi, Detlef K. Bartsch, Werner Hartwig, Martin K. Angele, Jan G. D’Haese, Jens Werner
Publikováno v:
BMC Surgery, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Non-resectability is common in patients with pancreatic ductal adenocarcinoma (PDAC) due to local invasion or distant metastases. Then, biliary or gastroenteric bypasses or both are often established despite associated morbidity a
Externí odkaz:
https://doaj.org/article/83c3e8e4cbb74cf59a3c87bb7f79b787
Autor:
Chung Shing Rex Ha, Martina Müller-Nurasyid, Agnese Petrera, Stefanie M Hauck, Federico Marini, Detlef K Bartsch, Emily P Slater, Konstantin Strauch
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280399 (2023)
BackgroundThe low five-year survival rate of pancreatic ductal adenocarcinoma (PDAC) and the low diagnostic rate of early-stage PDAC via imaging highlight the need to discover novel biomarkers and improve the current screening procedures for early di
Externí odkaz:
https://doaj.org/article/96931f55022e484289322de847023aee
Autor:
Sabine Wächter, Silvia Roth, Norman Gercke, Ulrike Schötz, Ekkehard Dikomey, Rita Engenhart-Cabillic, Elisabeth Maurer, Detlef K. Bartsch, Pietro Di Fazio
Publikováno v:
Life, Vol 13, Iss 6, p 1397 (2023)
Radiotherapy and immunotherapy have shown promising efficacy for the treatment of solid malignancies. Here, we aim to clarify the potential of a combined application of radiotherapy and programmed cell death-ligand 1 (PD-L1) monoclonal antibody atezo
Externí odkaz:
https://doaj.org/article/3ee6f125295c4a42903afedbaeba15c5
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
PurposeTo evaluate whether visualization of the colon perfusion with indocyanine green near-infrared fluoroangiography (ICG-NIFA) reduces the rate of anastomotic leakage (AL) after colorectal anastomosis.MethodsPatients who underwent elective left co
Externí odkaz:
https://doaj.org/article/42465f8729e94e739fa2fbe4356f2903
Autor:
Yesim Verel-Yilmaz, Juan Pablo Fernández, Agnes Schäfer, Sheila Nevermann, Lena Cook, Norman Gercke, Frederik Helmprobst, Christian Jaworek, Elke Pogge von Strandmann, Axel Pagenstecher, Detlef K. Bartsch, Jörg W. Bartsch, Emily P. Slater
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Due to a grim prognosis, there is an urgent need to detect pancreatic ductal adenocarcinoma (PDAC) prior to metastasis. However, reliable diagnostic imaging methods or biomarkers for PDAC or its precursor lesions are still scarce. ADAM8, a metallopro
Externí odkaz:
https://doaj.org/article/c3410811784b46d082946a8aab0a1d76
Autor:
Sabine Wächter, Franziska Knauff, Silvia Roth, Corinna Keber, Katharina Holzer, Jerena Manoharan, Elisabeth Maurer, Detlef K. Bartsch, Pietro Di Fazio
Publikováno v:
Cancer Investigation. 41:405-421
Anaplastic thyroid carcinoma (ATC) has poor prognosis, high mortality rate and lack of effective therapy. A synergic combination of PD-L1 antibody together with cell death promoting substances like deacetylase inhibitors (DACi) and multi-kinase inhib