Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Detlef Grunow"'
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200507 (2018)
Glycome modulations have been described in the onset and progression of many diseases. Thus, many studies have proposed glycans from blood glycoproteins as disease markers. Astonishingly, little effort has been given unraveling preanalytical conditio
Externí odkaz:
https://doaj.org/article/0a0b32d45aa843adb056282aaa746b13
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1934
Enzymatic sequencing of oligosaccharides provides structural information on sequence of monosaccharides and type of linkage within the oligosaccharide chain. This data can be obtained by stepwise enzymatic digestion of a single, isolated oligosacchar
Autor:
Detlef, Grunow, Véronique, Blanchard
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1934
Glycosylation, one of the most frequent protein posttranslational modifications, is involved in the mechanisms of cell-cell interactions and immune reactions and is modulated in the course of diseases. In contrary to chemical glycan release, enzymati
Autor:
Detlef Grunow, Véronique Blanchard
Publikováno v:
Post-Translational Modification of Proteins ISBN: 9781493990535
Glycosylation, one of the most frequent protein posttranslational modifications, is involved in the mechanisms of cell-cell interactions and immune reactions and is modulated in the course of diseases. In contrary to chemical glycan release, enzymati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45d0f568cc1f30b863dd7e2f9adceee9
https://doi.org/10.1007/978-1-4939-9055-9_4
https://doi.org/10.1007/978-1-4939-9055-9_4
Publikováno v:
Post-Translational Modification of Proteins ISBN: 9781493990535
Methods in Molecular Biology™ ISBN: 9781588297198
Methods in Molecular Biology™ ISBN: 9781588297198
Enzymatic sequencing of oligosaccharides gives structural information on sequence of monosaccharides and type of linkage within the oligosaccharide chain. This data can be obtained by stepwise enzymatic digestion of a single, isolated oligosaccharide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01d49ead24e018a2a7d8d930dba3614
https://doi.org/10.1007/978-1-4939-9055-9_5
https://doi.org/10.1007/978-1-4939-9055-9_5
Autor:
Martin Zimmermann-Kordmann, Thomas Jacobs, Daniel Gröbe, Detlef Grunow, Werner Reutter, Véronique Blanchard, Thorsten Lieke, Rudolf Tauber
Publikováno v:
Glycoconjugate Journal. 28:31-37
The etiologic agent of Chagas' disease, Trypanosoma cruzi, is widely distributed in South America, affecting millions of people with thousands of deaths every year. Adherence of the infectious trypomastigote to host cells is mediated by sialic acid.
Autor:
Peter Nollau, Christoph Wagener, Lothar Lucka, Valentina Bogoevska, Carl G. Gahmberg, Liisa M. Uotila, Alexandra Samsen, Birgit Klampe, Detlef Grunow
Publikováno v:
Glycobiology. 17:324-333
Intercellular adhesion molecule-3 (ICAM-3) binds to the alpha(L)beta(2) integrin and mediates the contact between T cells and antigen-presenting cells. It has been suggested that dendritic cell-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a C-type
Autor:
Stefan Porwoll, Christoph Kannicht, Detlef Grunow, Rudolf Tauber, Werner Reutter, Nikolaus Loch, Rolf Nuck
Publikováno v:
Journal of Biological Chemistry. 273:1075-1085
Primary rat hepatocytes and two hepatoma cell lines have been used to study whether high mannose-type N-glycans of plasma membrane glycoproteins may be modified by the removal of mannose residues even after transport to the cell surface. To examine g
Autor:
Peter Bringmann, Werner Reutter, Rolf Nuck, Detlef Grunow, Christoph Kannicht, Günther Baude, Martin Gohlke, Peter Donner
Publikováno v:
Journal of Biological Chemistry. 271:7381-7386
DSPAalpha1 (Desmodus rotundus salivary plasminogen activator), a plasminogen activator from the saliva of the vampire bat Desmodus rotundus, is an effective thrombolytic agent. An unusual type of posttranslational modification, in which L-fucose is O
Autor:
Rolf Nuck, Reinhard Zeitler, Detlef Grunow, Holger Kayser, Werner Reutter, Christoph Kannicht
Publikováno v:
Journal of Biological Chemistry. 267:16934-16938
In this study it could be shown that in rat the normally occurring N-acetyl neuraminic acid can be modified in its N-acyl moiety by in vivo administration of the chemically synthesized N-propanoyl precursors, N-propanoyl-D-glucosamine or N-propanoyl-