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pro vyhledávání: '"Detlef Geiges"'
Autor:
Josef Pfeilschifter, Mirka Vanek, Detlef Geiges, Thomas Meyer, Georges Weissgerber, Doriano Fabbro, Andrea Huwiler, Silvia Stabel, Barbara M. Marte
Publikováno v:
Biochemical Pharmacology. 53:865-875
Protein kinase C (PKC) subtypes alpha, gamma, delta, epsilon, zeta, and eta have been expressed using the baculovirus expression system. The partially purified PKC subtypes have been studied for their substrate specificities and phospholipid-independ
Publikováno v:
Experimental Cell Research. 219:299-303
The spontaneously immortalized human skin keratinocytes HaCaT contain protein kinase C (PKC) alpha, -delta, -epsilon, and -zeta. All PKC isoenzymes except PKC zeta are down-regulated by TPA as well as by bryostatin. However, with PKC delta, bryostati