Neurotensin(8-13) analogs as dual NTS1 and NTS2 receptor ligands with enhanced effects on a mouse model of Parkinson's disease.

Autor: Kühl T; Pharmaceutical Biochemistry and Bioanalytics, Pharmaceutical Institute, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany., Georgieva MG; Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology 'Roumen Tsanev', Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, Sofia, 1113, Bulgaria., Hübner H; Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander- Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, D-91058, Erlangen, Germany., Lazarova M; Institute of Neurobiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 23, 1113, Sofia, Bulgaria., Vogel M; Federal Institute for Drugs and Medical Devices (BfArM), Kurt-Georg-Kiesinger-Allee 3, 53175, Bonn, Germany., Haas B; Federal Institute for Drugs and Medical Devices (BfArM), Kurt-Georg-Kiesinger-Allee 3, 53175, Bonn, Germany., Peeva MI; Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology 'Roumen Tsanev', Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, Sofia, 1113, Bulgaria., Balacheva AA; Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology 'Roumen Tsanev', Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, Sofia, 1113, Bulgaria., Bogdanov IP; Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology 'Roumen Tsanev', Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, Sofia, 1113, Bulgaria., Milella L; Department of Science, University of Basilicata, V.le dell'Ateneo Lucano 10, 85100, Potenza, Italy., Ponticelli M; Department of Science, University of Basilicata, V.le dell'Ateneo Lucano 10, 85100, Potenza, Italy., Garev T; UMBALSM 'N. I. Pirogov'-Hospital, 1606 Pette Kyosheta, Sofia, Bulgaria., Faraone I; Department of Science, University of Basilicata, V.le dell'Ateneo Lucano 10, 85100, Potenza, Italy; Innovative Startup Farmis s.r.l., Via Nicola Vaccaro 40, 85100, Potenza, Italy., Detcheva R; Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology 'Roumen Tsanev', Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, Sofia, 1113, Bulgaria., Minchev B; Institute of Neurobiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 23, 1113, Sofia, Bulgaria., Petkova-Kirova P; Institute of Neurobiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 23, 1113, Sofia, Bulgaria., Tancheva L; Institute of Neurobiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 23, 1113, Sofia, Bulgaria; Weizmann Institute of Science, 234 Herzl St., Rehovot, 7610001, Israel., Kalfin R; Institute of Neurobiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 23, 1113, Sofia, Bulgaria., Atanasov AG; Ludwig Boltzmann Institute for Digital Health and Patient Safety, Medical University of Vienna, Spitalgasse 23, 1090, Vienna, Austria; Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences, Jastrzebiec, 05-552, Magdalenka, Poland., Antonov L; Institute of Electronics, Bulgarian Academy of Sciences, Blvd. Tsarigradsko Chaussee 72, 1784, Sofia, Bulgaria., Pajpanova TI; Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology 'Roumen Tsanev', Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, Sofia, 1113, Bulgaria., Kirilov K; Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology 'Roumen Tsanev', Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, Sofia, 1113, Bulgaria; Department of Natural Sciences, New Bulgarian University, 21 Montevideo Str., Sofia, 1618, Bulgaria., Gastreich M; BioSolveIT GmbH, An der Ziegelei 79, 53757 St. Augustin, Germany., Gmeiner P; Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander- Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, D-91058, Erlangen, Germany., Imhof D; Pharmaceutical Biochemistry and Bioanalytics, Pharmaceutical Institute, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany., Tzvetkov NT; Department of Biochemical Pharmacology and Drug Design, Institute of Molecular Biology 'Roumen Tsanev', Bulgarian Academy of Sciences, Acad. G. Bonchev Str., bl. 21, Sofia, 1113, Bulgaria. Electronic address: ntzvetkov@bio21.bas.bg.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2023 Jun 05; Vol. 254, pp. 115386. Date of Electronic Publication: 2023 Apr 17.

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4-Hydroxybenzoic Acid-Based Hydrazide–Hydrazones as Potent Growth Inhibition Agents of Laccase-Producing Phytopathogenic Fungi That Are Useful in the Protection of Oilseed Crops.

Autor: Maniak, Halina¹ (AUTHOR) halina.maniak@pwr.edu.pl, Matyja, Konrad¹ (AUTHOR) anna.trusek@pwr.edu.pl, Pląskowska, Elżbieta² (AUTHOR) elzbieta.plaskowska@upwr.edu.pl, Jarosz, Joanna³ (AUTHOR) joanna.jarosz@iitd.pan.wroc.pl, Majewska, Paulina⁴ (AUTHOR) paulina_majewska7@tlen.pl, Wietrzyk, Joanna³ (AUTHOR) wietrzyk@iitd.pan.wroc.pl, Gołębiowska, Hanna⁵ (AUTHOR) hanna.golebiowska1@wp.pl, Trusek, Anna¹ (AUTHOR), Giurg, Mirosław⁶ (AUTHOR) halina.maniak@pwr.edu.pl

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