Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Desy S Lee"'
Autor:
Sunny Sun-Kin Chan, Hui-Jing Li, Ying-Chang Hsueh, Desy S Lee, Jyh-Hong Chen, Shiaw-Min Hwang, Chen-Yun Chen, Emily Shih, Patrick C H Hsieh
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14414 (2010)
BACKGROUND: The fibroblast growth factor (FGF) family is essential to normal heart development. Yet, its contribution to cardiomyocyte differentiation from stem cells has not been systemically studied. In this study, we examined the mechanisms and ch
Externí odkaz:
https://doaj.org/article/703a457db3394fbfbe46407deeb5b360
Autor:
Chen-Yun Chen, Desy S. Lee, Oi Kuan Choong, Sheng-Kai Chang, Tien Hsu, Martin W. Nicholson, Li-Wei Liu, Po-Ju Lin, Shu-Chian Ruan, Shu-Wha Lin, Chung-Yi Hu, Patrick C. H. Hsieh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract MicroRNA-125b, the first microRNA to be identified, is known to promote cardiomyocyte maturation from embryonic stem cells; however, its physiological role remains unclear. To investigate the role of miR-125b in cardiovascular biology, cardi
Externí odkaz:
https://doaj.org/article/4026093012a24238a07b583c66e4a5a9
Publikováno v:
Non-coding RNA Research, Vol 2, Iss 2, Pp 100-110 (2017)
The emergence of non-coding RNAs (ncRNAs) has challenged the central dogma of molecular biology that dictates that the decryption of genetic information starts from transcription of DNA to RNA, with subsequent translation into a protein. Large number
Externí odkaz:
https://doaj.org/article/dc8374c058c7456a87dd537d8072c529
Autor:
Sheng-Kai Chang, Chung-Yi Hu, Oi Kuan Choong, Desy S. Lee, Patrick C.H. Hsieh, Po-Ju Lin, Shu-Wha Lin, Martin W. Nicholson, Tien Hsu, Shu-Chian Ruan, Chen-Yun Chen, Li-Wei Liu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
MicroRNA-125b, the first microRNA to be identified, is known to promote cardiomyocyte maturation from embryonic stem cells; however, its physiological role remains unclear. To investigate the role of miR-125b in cardiovascular biology, cardiac-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b470e0adb1e51fcb8cb08844237ada38
https://doi.org/10.1038/s41598-021-81700-y
https://doi.org/10.1038/s41598-021-81700-y
Autor:
Sho Tone Lee, Desy S. Lee, Chen-Yun Chen, Shiaw-Min Hwang, Yu-Ting Yan, Chia-Ning Shen, Patrick C.H. Hsieh
Publikováno v:
Stem Cells. 33:3468-3480
Leukemia inhibitory factor (LIF) regulates mouse embryonic stem cell (mESC) pluripotency through STAT3 activation, but the downstream signaling remains largely unelucidated. Using cDNA microarrays, we verified B cell leukemia/lymphoma 3 (Bcl3) as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20c79cc046da9755c05c94d0f696149
https://doi.org/10.1002/stem.2201
https://doi.org/10.1002/stem.2201
Publikováno v:
Cardiovascular Research. 114:S69-S69
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab1142f934ae86bc2a209a51d125e1d6
https://doi.org/10.1093/cvr/cvy060.190
https://doi.org/10.1093/cvr/cvy060.190
Publikováno v:
Annals of Translational Medicine. 5:143-143
There is a growing need for in vitro models which can serve as platforms for drug screening and basic research. Human adult cardiomyocytes cannot be readily obtained or cultured, and so pluripotent stem cell-derived cardiomyocytes appear to be an att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447e869e5ea2b4bee5a771f13a7e5469
https://doi.org/10.21037/atm.2017.01.44
https://doi.org/10.21037/atm.2017.01.44
Autor:
Chen Yun Chen, Emily Shih, Shiaw-Min Hwang, Sunny Sun Kin Chan, Patrick C.H. Hsieh, Ying Chang Hsueh, Hui Jing Li, Desy S. Lee, Jyh Hong Chen
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14414 (2010)
PLoS ONE
PLoS ONE
Background The fibroblast growth factor (FGF) family is essential to normal heart development. Yet, its contribution to cardiomyocyte differentiation from stem cells has not been systemically studied. In this study, we examined the mechanisms and cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae5a7271611d3024643195a531bd61f
https://doi.org/10.1371/journal.pone.0014414
https://doi.org/10.1371/journal.pone.0014414
Autor:
Shiaw-Min Hwang, Po Min Chiang, Sheng Nan Wu, Patrick C.H. Hsieh, Yu-Ting Yan, Shu Chien, Sho Tone Lee, Chung Hung Liu, Charles E. Murry, David J. Lundy, Chien-Chang Chen, Ru-Chi Shieh, Jyh Hong Chen, Lil Pabon, Desy S. Lee
Publikováno v:
Cell Reports, Vol 12, Iss 12, Pp 1960-1967 (2015)
SummaryPluripotent-cell-derived cardiomyocytes have great potential for use in research and medicine, but limitations in their maturity currently constrain their usefulness. Here, we report a method for improving features of maturation in murine and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771f0035b8f24dfca0901caf83517bee
Autor:
Desy S. Lee, Jyh-Hong Chen, David J. Lundy, Chung-Hung Liu, Shiaw-Min Hwang, Lil Pabon, Ru-Chi Shieh, Chien-Chang Chen, Sheng-Nan Wu, Yu-Ting Yan, Sho-Tone Lee, Po-Min Chiang, Shu Chien, Charles E. Murry, Patrick C.H. Hsieh
Publikováno v:
Cell Reports, Vol 12, Iss 12, Pp 1960-1967 (2015)
Pluripotent-cell-derived cardiomyocytes have great potential for use in research and medicine, but limitations in their maturity currently constrain their usefulness. Here, we report a method for improving features of maturation in murine and human e
Externí odkaz:
https://doaj.org/article/1e5368eca16c4c6fb87703916969648c