Primary and Immortalized Human Respiratory Cells Display Different Patterns of Cytotoxicity and Cytokine Release upon Exposure to Deoxynivalenol, Nivalenol and Fusarenon-X

Autor: Silvia Ferreira Lopes, Gaëlle Vacher, Eleonora Ciarlo, Dessislava Savova-Bianchi, Thierry Roger, Hélène Niculita-Hirzel

Publikováno v: Toxins, Vol 9, Iss 11, p 337 (2017)

The type B trichothecene mycotoxins deoxynivalenol (DON), nivalenol (NIV) and fusarenon-X (FX) are structurally related secondary metabolites frequently produced by Fusarium on wheat. Consequently, DON, NIV and FX contaminate wheat dusts, exposing gr

Externí odkaz: https://doaj.org/article/5e4dfeb0c62e462797b15ea854a14430

Exposure to field vs. storage wheat dust: different consequences on respiratory symptoms and immune response among grain workers

Autor: Gabriel Reboux, Pascal Wild, Coralie Barrera, Hélène Niculita-Hirzel, Victor Dorribo, Laurence Millon, Peggy Krief, Dessislava Savova-Bianchi, Audrey Laboissière, Brigitta Danuser, Jacques A. Pralong

Publikováno v: International Archives of Occupational and Environmental Health, vol. 91, no. 6, pp. 745-757
International Archives of Occupational and Environmental Health
International Archives of Occupational and Environmental Health, Springer Verlag, 2018, 91 (6), pp.745-757. ⟨10.1007/s00420-018-1322-7⟩

The aim of this study was to understand the differential acute effects of two distinct wheat-related dusts, such as field or stored wheat dust handling, on workers' health and how those effects evolved at 6 month intervals. Exposure, work-related sym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f2096a669331f53b3a870f3affc23b
https://serval.unil.ch/resource/serval:BIB_D11C396C227A.P001/REF.pdf

Innate Immune Sensing ofFusarium culmorumby Mouse Dendritic Cells

Autor: Hélène Niculita-Hirzel, Eleonora Ciarlo, Gregoire Hantier, Thierry Roger, Didier Le Roy, Dessislava Savova-Bianchi, Gaëlle Vacher

Publikováno v: Journal of Toxicology and Environmental Health-Part a-Current Issues

Chronic inhalation of grain dust is associated with asthma and chronic bronchitis in grain worker populations. Exposure to fungal particles was postulated to be an important etiologic agent of these pathologies. Fusarium species frequently colonize g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc60064ba16e90a2ae81a935be9d575f
https://doi.org/10.1080/15287394.2015.1051201

Workers exposed to wood dust have an increased micronucleus frequency in nasal and buccal cells: results from a pilot study

Autor: Nancy B. Hopf, Evin Danisman Bruschweiler, Pascal Wild, Nicole Charrière, Brigitta Danuser, Dessislava Savova-Bianchi, Maryam Hor, Michael Fenech, Philip Thomas, Cong Khanh Huynh

Publikováno v: Mutagenesis. 29:201-207

Wood dust is recognised as a human carcinogen, based on the strong association of wood dust exposure and the elevated risk of malignant tumours of the nasal cavity and paranasal sinuses [sino-nasal cancer (SNC)]. The study aimed to assess genetic dam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba8b46839e507e7ca2905044085ba88
https://doi.org/10.1093/mutage/geu003

Assessment of airborne virus contamination in wastewater treatment plants

Autor: Anne Oppliger, Frédéric G. Masclaux, Drita Gashi, Philipp Hotz, Dessislava Savova-Bianchi

Publikováno v: Environmental Research, vol. 133, pp. 260-265

Introduction Occupational exposure to bioaerosols in wastewater treatment plants (WWTP) and its consequence on workers׳ health are well documented. Most studies were devoted to enumerating and identifying cultivable bacteria and fungi, as well as me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d99b189e11855053f6a31693d7600f22
https://pubmed.ncbi.nlm.nih.gov/24981824