Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Despina Soteriou"'
Autor:
Inbal Maniv, Mahasen Sarji, Anwar Bdarneh, Alona Feldman, Roi Ankawa, Elle Koren, Inbar Magid-Gold, Noa Reis, Despina Soteriou, Shiran Salomon-Zimri, Tali Lavy, Ellina Kesselman, Naama Koifman, Thimo Kurz, Oded Kleifeld, Daniel Michaelson, Fred W. van Leeuwen, Bert M. Verheijen, Yaron Fuchs, Michael H. Glickman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Alzheimer’s disease (AD) is characterized by toxic protein accumulation in the brain. Ubiquitination is essential for protein clearance in cells, making altered ubiquitin signaling crucial in AD development. A defective variant, ubiquitin
Externí odkaz:
https://doaj.org/article/74e57d7f81c342d092153d856a153d11
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104016- (2022)
Summary: Atomic force microscopy (AFM) is widely used for quantifying the mechanical properties of soft materials such as cells. AFM force-indentation curves are conventionally fitted with a Hertzian model to extract elastic properties. These propert
Externí odkaz:
https://doaj.org/article/d43aba00d43a4f1985cf74e4fce46f50
Autor:
Martin Kräter, Shada Abuhattum, Despina Soteriou, Angela Jacobi, Thomas Krüger, Jochen Guck, Maik Herbig
Publikováno v:
Advanced Science, Vol 8, Iss 11, Pp n/a-n/a (2021)
Abstract Artificial intelligence (AI)‐based image analysis has increased drastically in recent years. However, all applications use individual solutions, highly specialized for a particular task. Here, an easy‐to‐use, adaptable, and open source
Externí odkaz:
https://doaj.org/article/4948e2f8e69840fd9dcc3b12d05b14be
Autor:
Elle Koren, Yahav Yosefzon, Roi Ankawa, Despina Soteriou, Avi Jacob, Alexander Nevelsky, Rahamim Ben-Yosef, Gil Bar-Sela, Yaron Fuchs
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The mechanisms regulating intestinal stem cell elimination remain unclear. Here, the authors identify that the pro-apoptotic protein ARTS (a Septin4 isoform) interacts with XIAP in the intestinal stem cell niche to regulate stem cell survival during
Externí odkaz:
https://doaj.org/article/3d2bd9fa6b9944f6b5e42563b3ccacf7
Autor:
Waseem Nasser, Aya Amitai-Lange, Despina Soteriou, Rana Hanna, Beatrice Tiosano, Yaron Fuchs, Ruby Shalom-Feuerstein
Publikováno v:
Cell Reports, Vol 22, Iss 2, Pp 323-331 (2018)
Summary: During morphogenesis, preserving tissue boundaries is essential for cell fate regulation. While embryonic tissues possess high plasticity and repair ability, the questions of whether and how adult tissues cope with acute stem cell (SC) loss
Externí odkaz:
https://doaj.org/article/d5c4b37b56c4485b8df1cf6b4053da3f
Autor:
Jinpei Ye, Nicola Bates, Despina Soteriou, Lisa Grady, Clare Edmond, Alex Ross, Alan Kerby, Philip A. Lewis, Tope Adeniyi, Ronnie Wright, Kay V. Poulton, Marcus Lowe, Susan J. Kimber, Daniel R. Brison
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-13 (2017)
Abstract Background Human embryonic stem cells (hESCs) hold tremendous promise for cell replacement therapies for a range of degenerative diseases. In order to provide cost-effective treatments affordable by public health systems, HLA-matched allogen
Externí odkaz:
https://doaj.org/article/057a476c34c54430a3b0a380c431892e
Autor:
Alexandru‐Emil Matei, Markéta Kubánková, Liyan Xu, Andrea‐Hermina Györfi, Evgenia Boxberger, Despina Soteriou, Maria Papava, Julia Prater, Xuezhi Hong, Christina Bergmann, Martin Kräter, Georg Schett, Jochen Guck, Jörg H. W. Distler
Publikováno v:
Arthritis & Rheumatology
ObjectivePathologically activated circulating immune cells, including monocytes, play major roles in systemic sclerosis (SSc). Their functional characterization can provide crucial information with direct clinical relevance. However, tools for the ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e611733706f82a5e0bd08e5372f3096f
https://hdl.handle.net/21.11116/0000-000C-CDAE-A21.11116/0000-000D-0A87-0
https://hdl.handle.net/21.11116/0000-000C-CDAE-A21.11116/0000-000D-0A87-0
Autor:
Despina Soteriou, Markéta Kubánková, Christine Schweitzer, Rocío López-Posadas, Rashmita Pradhan, Oana-Maria Thoma, Andrea-Hermina Györfi, Alexandru-Emil Matei, Maximilian Waldner, Jörg H. W. Distler, Stefan Scheuermann, Jens Langejürgen, Markus Eckstein, Regine Schneider-Stock, Raja Atreya, Markus F. Neurath, Arndt Hartmann, Jochen Guck
Publikováno v:
nature biomedical engineering
During surgery, rapid and accurate histopathological diagnosis is essential for clinical decision making. Yet the prevalent method of intra-operative consultation pathology is intensive in time, labour and costs, and requires the expertise of trained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760e0d54fbfa22e893d53d8f7e1d18c6
https://hdl.handle.net/21.11116/0000-000C-F245-521.11116/0000-0009-9484-A
https://hdl.handle.net/21.11116/0000-000C-F245-521.11116/0000-0009-9484-A
Autor:
Luz del Carmen Martínez-Sánchez, Phuong Anh Ngo, Rashmita Pradhan, Lukas-Sebastian Becker, David Boehringer, Despina Soteriou, Marketa Kubankova, Christine Schweitzer, Tatyana Koch, Veronika Thonn, Lena Erkert, Iris Stolzer, Claudia Günther, Christoph Becker, Benno Weigmann, Monika Klewer, Christoph Daniel, Kerstin Amann, Stefan Tenzer, Raja Atreya, Martin Bergo, Cord Brakebusch, Alastair J M Watson, Jochen Guck, Ben Fabry, Imke Atreya, Markus F Neurath, Rocío López-Posadas
Publikováno v:
Martínez-Sánchez, L D C, Ngo, P A, Pradhan, R, Becker, L-S, Boehringer, D, Soteriou, D, Kubankova, M, Schweitzer, C, Koch, T, Thonn, V, Erkert, L, Stolzer, I, Günther, C, Becker, C, Weigmann, B, Klewer, M, Daniel, C, Amann, K, Tenzer, S, Atreya, R, Bergo, M, Brakebusch, C, Watson, A J M, Guck, J, Fabry, B, Atreya, I, Neurath, M F & López-Posadas, R 2023, ' Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation ', Gut, vol. 72, no. 2, pp. 275-294 . https://doi.org/10.1136/gutjnl-2021-325520
Gut
Gut
ObjectiveIncreased apoptotic shedding has been linked to intestinal barrier dysfunction and development of inflammatory bowel diseases (IBD). In contrast, physiological cell shedding allows the renewal of the epithelial monolayer without compromising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16fe74d36fb6f2e53d3dc23124ec32a
https://ueaeprints.uea.ac.uk/id/eprint/83973/
https://ueaeprints.uea.ac.uk/id/eprint/83973/
Autor:
Ahmad Ahsan Nawaz, Despina Soteriou, Catherine K. Xu, Ruchi Goswami, Maik Herbig, Jochen Guck, Salvatore Girardo
Publikováno v:
Lab on a Chip
Sorting cells is an essential primary step in many biological and clinical applications such as high-throughput drug screening, cancer research and cell transplantation. Cell sorting based on their mechanical properties has long been considered as a