Correction to: Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution

Autor: Vaia Florou, Andrew E. Rosenberg, Eric Wieder, Krishna V. Komanduri, Despina Kolonias, Mohamed Uduman, John C. Castle, Jennifer S. Buell, Jonathan C. Trent, Breelyn A. Wilky

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-1 (2019)

Following publication of the original article [1], the authors have reported that the following sentence “While of the same IgG1 class as ipilimumab, preclinical data suggests this molecule may have enhanced activity against T regulatory cells”.

Externí odkaz: https://doaj.org/article/e32b3b6c9236477c9ca35134e4621765

Deep functional immunophenotyping predicts risk of cytomegalovirus reactivation after hematopoietic cell transplantation

Autor: Eric D. Wieder, Krishna V. Komanduri, Deukwoo Kwon, Erik Kimble, Cara L. Benjamin, Jose F. Camargo, Xi Steven Chen, Despina Kolonias

Publikováno v: Blood. 133:867-877

Cytomegalovirus (CMV) is the most common viral infection in hematopoietic cell transplantation (HCT) recipients. We performed deep phenotyping of CMV-specific T cells to predict CMV outcomes following allogeneic HCT. By using 13-color flow cytometry,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70111f3f127ad268c61febcc7991437b
https://doi.org/10.1182/blood-2018-10-878918

Correction to: Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution

Autor: Andrew E. Rosenberg, Jonathan C. Trent, Vaia Florou, Breelyn A. Wilky, John C. Castle, Mohamed Uduman, Despina Kolonias, Eric D. Wieder, Krishna V. Komanduri, Jennifer Buell

Publikováno v: Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-1 (2019)
Journal for immunotherapy of cancer, vol 7, iss 1

Angiosarcoma is an uncommon endothelial malignancy and a highly aggressive soft tissue sarcoma. Due to its infiltrative nature, successful management of localized angiosarcoma is often challenging. Systemic chemotherapy is used in the metastatic sett

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6549621f3f50374444b04fb87f532718
http://europepmc.org/articles/PMC6833228

Axitinib plus pembrolizumab in patients with advanced sarcomas including alveolar soft-part sarcoma: a single-centre, single-arm, phase 2 trial

Autor: Deukwoo Kwon, Jaime R. Merchan, Ty K. Subhawong, Breelyn A. Wilky, Matteo Trucco, Vaia Florou, Jonathan C. Trent, Eric D. Wieder, Andrew E. Rosenberg, Darcy A. Kerr, Despina Kolonias, Efrosyni Sfakianaki, Krishna V. Komanduri, Mark Foley, Wungki Park

Publikováno v: The Lancet. Oncology. 20(6)

Summary Background VEGF promotes an immunosuppressive microenvironment and contributes to immune checkpoint inhibitor resistance in cancer. We aimed to assess the activity of the VEGF receptor tyrosine-kinase inhibitor axitinib plus the anti-PD-1 imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377d16b365aeb4035901cd9b0f0170ec
https://pubmed.ncbi.nlm.nih.gov/31078464

Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay

Autor: Fernando Pastor, Despina Kolonias, Paloma H. Giangrande, Eli Gilboa

Publikováno v: Nature. 465:227-230

Whereas tumor progression in cancer patients can elicit a weak immune response which keeps the tumor in check, albeit transiently, the weak antigenicity of the tumor provides the time and opportunity for the tumor to elaborate immune evasion mechanis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb9cc18748d64a1a62687e8c5171f5d
https://doi.org/10.1038/nature08999