Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Desmond She"'
Autor:
Ming-Sound Tsao, Frances A. Shepherd, Melania Pintilie, Chang-Qi Zhu, Shingo Sakashita, Desmond She, David W. Cescon
Purpose: Genomic profiling of lung squamous cell carcinomas (SCC) has identified NRF2 pathway alterations, which activate oxidative response pathways, in one third of tumors. Preclinical data suggest these tumors may be resistant to platinum-based ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74937c7a4b87e1a5a81ba6acac9b0978
https://doi.org/10.1158/1078-0432.c.6524135.v1
https://doi.org/10.1158/1078-0432.c.6524135.v1
Autor:
Ming-Sound Tsao, Frances A. Shepherd, Melania Pintilie, Chang-Qi Zhu, Shingo Sakashita, Desmond She, David W. Cescon
Supplemental Tables S1-2 and Figures S1-2. Table S1 - primers used for sequencing of NRF2 and KEAP1; Table S2 - Lists of differentially expressed genes comprising NRF2ACT signature; Figure S1- Distribution of NRF2 and KEAP1 IHC H-scores; Figure S2 -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e56339dfa58a8c33c6debba5a2609e
https://doi.org/10.1158/1078-0432.22459124
https://doi.org/10.1158/1078-0432.22459124
Autor:
Chang-Qi Zhu, Melania Pintilie, Desmond She, Frances A. Shepherd, Shingo Sakashita, David W. Cescon, Ming-Sound Tsao
Publikováno v:
Clinical Cancer Research. 21:2499-2505
Purpose: Genomic profiling of lung squamous cell carcinomas (SCC) has identified NRF2 pathway alterations, which activate oxidative response pathways, in one third of tumors. Preclinical data suggest these tumors may be resistant to platinum-based ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135de72cf152ecfb74c7aec58d5fafd2
https://doi.org/10.1158/1078-0432.ccr-14-2206
https://doi.org/10.1158/1078-0432.ccr-14-2206
Autor:
Carl Laflamme, Paul S. Maddox, Desmond She, Jonas F. Dorn, Damien Ramel, Gregory Emery, Gloria Assaker
Publikováno v:
The Journal of Cell Biology
Drosophila Evi5 is a Rab-GAP that acts on the membrane-trafficking mediator Rab11 to promote guidance receptor polarization during border cell migration.
Membrane trafficking has well-defined roles during cell migration. However, its regulation
Membrane trafficking has well-defined roles during cell migration. However, its regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198f26574e073fe844c24dc0505bf43a
http://europepmc.org/articles/PMC3392932
http://europepmc.org/articles/PMC3392932
Autor:
David W. Cescon, Melania Pintilie, Desmond She, Ming-Sound Tsao, Shingo Sakashita, Frances A. Shepherd, Chang-Qi Zhu
Publikováno v:
Journal of Clinical Oncology. 31:7517-7517
7517 Background: Genomic profiling of SqCC in TCGA identified somatic alterations that activate the NRF2 transcriptional program – a master regulator of the oxidative stress response – in ~35% of tumors (NFE2L2 mutations/amplifications, KEAP1 or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::756ac2f04237f92e70d7a4318bac8e65
https://doi.org/10.1200/jco.2013.31.15_suppl.7517
https://doi.org/10.1200/jco.2013.31.15_suppl.7517