Výsledky vyhledávání - "Desmond O'Leary"

MP17-08 CLINICAL VALIDATION OF A NOVEL SIX-GENE RISK-STRATIFICATION SIGNATURE TO SUPPORT TREATMENT DECISIONS FOR MEN DIAGNOSED WITH PROSTATE CANCER

Autor: Agnieszka Krzyzanowska, Stephen Barron, Debra F. Higgins, Tony Loughman, Katherine M. Sheehan, Angel Chan-Ju Wang, Bozena Fender, Leah M. McGuire, David Galvin, Amanda O'Neil, Joanna Fay, Anthony O'Grady, Desmond O'Leary, R. William. G. Watson, Anders Bjartell, William M. Gallagher

Publikováno v: Journal of Urology. 209

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ab3a1e084eabfe100583bc4f18228dd
https://doi.org/10.1097/ju.0000000000003237.08

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Analytical Validation of a Novel 6-Gene Signature for Prediction of Distant Recurrence in Estrogen Receptor-Positive, HER2-Negative, Early-Stage Breast Cancer

Publikováno v: Clinical chemistry. 68(6)

Background OncoMasTR is a recently developed multigene prognostic test for early-stage breast cancer. The test has been developed in a kit-based format for decentralized deployment in molecular pathology laboratories. The analytical performance chara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193b09548b16f523d363b61704f5ab4d
https://pubmed.ncbi.nlm.nih.gov/35312747

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Abstract P4-08-31: Withdrawn

Autor: Cecily Quinn, Aurelie Fabre, Karin Jirström, Desmond O'Leary, Tony Loughman, Adrian P. Bracken, C-Ja Wang, Peter Dynoodt, C Lopez-Ruiz, S. Stapleton, William M. Gallagher, Bozena Fender, Björn Nodin, Stephen Barron

Publikováno v: Cancer Research. 79:P4-08

This abstract was withdrawn by the authors. Citation Format: Loughman T, Wang C-JA, Dynoodt P, Fender B, Lopez-Ruiz C, Barron S, Stapleton S, O'Leary D, Fabre A, Quinn C, Nodin B, Jirström K, Bracken A, Gallagher WM. Withdrawn [abstract]. In: Procee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d616fe89d235b977c871404114efd00
https://doi.org/10.1158/1538-7445.sabcs18-p4-08-31

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Prognostic value of the 6-gene OncoMasTR test in hormone receptor-positive HER2-negative early-stage breast cancer: Comparative analysis with standard clinicopathological factors

Publikováno v: European journal of cancer (Oxford, England : 1990). 152

The aim of the study was to assess the prognostic performance of a 6-gene molecular score (OncoMasTR Molecular Score [OMm]) and a composite risk score (OncoMasTR Risk Score [OM]) and to conduct a within-patient comparison against four routinely used

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b6d60eb5c7a208e2276d96bf897889
https://pubmed.ncbi.nlm.nih.gov/34090143

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Additional prognostic value of OncoMasTR multigene prognostic signature to clinicopathological information in patients with HR-positive, HER2-negative, lymph node-negative breast cancer from the TAILORx Tissue Bank, Ireland

Publikováno v: Journal of Clinical Oncology. 37:535-535

535 Background: Multigene prognostic signatures (MGPS) can identify early stage breast cancer patients who may require less aggressive treatment. To be clinically useful, MGPSs must provide additional prognostic information to clinicopathological inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c540df0563f78a7299e3bee76889b7c8
https://doi.org/10.1200/jco.2019.37.15_suppl.535

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Analytical validation of OncoMasTR, a multigene test for predicting risk of distant recurrence in hormone receptor-positive early stage breast cancer

Autor: Cecily Quinn, Karin Jirström, Aurelie Fabre, Desmond O'Leary, Björn Nodin, Adrian P. Bracken, Tony Loughman, William M. Gallagher, C. Lopez Ruiz, Bozena Fender, Stephen Barron, Peter Dynoodt, A. Chan-Ju Wang, S. Stapleton

Publikováno v: Annals of Oncology. 29:viii65

Background: OncoMasTR is a new multigene prognostic test that was discovered via a novel transcriptional network analysis method that identified upstream Master Transcription Regulators (MTRs), which regulate previously identified prognostic biomarke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3eef1118aa08d45bb1cfd15430af5a2d
https://doi.org/10.1093/annonc/mdy270.199

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Comparison of the prognostic performance between OncoMasTR and OncotypeDX multigene signatures in hormone receptor-positive, HER2-negative, lymph node-negative breast cancer

Autor: Seodhna M. Lynch, Verena Amberger-Murphy, Joanna Fay, Katherine M. Sheehan, Niamh Russell, Anthony O'Grady, Stephen Barron, Darran P. O'Connor, Catherine M. Kelly, Bozena Fender, John Crown, Anurati Saha, Chan-Ju Angel Wang, Tony Loughman, Desmond O'Leary, Peter Dynoodt, Cesar Lopez Ruiz, William M. Gallagher

Publikováno v: Journal of Clinical Oncology. 36:12074-12074

12074Background: Multigene prognostic signatures (MGPS) enable identification of early stage breast cancer (BC) patients requiring less aggressive treatment. OncoMasTR is a new MGPS found via a nov...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e91cb8911a697453015b661891bbb939
https://doi.org/10.1200/jco.2018.36.15_suppl.12074

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Evaluation of the OncoMasTR prognostic signature in postmenopausal women with primary ER-positive breast cancer

Autor: Richard Buus, Cesar Lopez Ruiz, Desmond O'Leary, Tony Loughman, Ivana Sestak, Chan-Ju Angel Wang, Jack Cuzick, William M. Gallagher, Peter Dynoodt, Bozena Fender, Mitchell Dowsett, Stephen Barron

Publikováno v: Journal of Clinical Oncology. 36:553-553

553Background: The assessment of distant recurrence (DR) risk in patients with early estrogen receptor (ER) positive breast cancer receiving adjuvant endocrine therapy is essential in making decisi...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf6fe36e49c27c4edf12b01b5a5e3e4b
https://doi.org/10.1200/jco.2018.36.15_suppl.553

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