Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Desmond N. Jackson"'
Autor:
Cho X. J. Chan, Sofiane El-Kirat-Chatel, Ivor G. Joseph, Desmond N. Jackson, Caleen B. Ramsook, Yves F. Dufrêne, Peter N. Lipke
Publikováno v:
mSphere, Vol 1, Iss 4 (2016)
ABSTRACT Many fungal adhesins have short, β-aggregation-prone sequences that play important functional roles, and in the Candida albicans adhesin Als5p, these sequences cluster the adhesins after exposure to shear force. Here, we report that Sacchar
Externí odkaz:
https://doaj.org/article/65b42140a4394f67846fdf7799990f66
Publikováno v:
mBio, Vol 7, Iss 1 (2016)
ABSTRACT There is increasing evidence that many amyloids in living cells have physiological functions. On the surfaces of fungal cells, amyloid core sequences in adhesins can aggregate into 100- to 1,000-nm-wide patches to form high-avidity adhesion
Externí odkaz:
https://doaj.org/article/358f61866c054fd7b5f3a8d69a8297ca
Autor:
Yves F. Dufrêne, Peter N. Lipke, Stephen A. Klotz, Desmond N. Jackson, Melissa C. Garcia-Sherman
Publikováno v:
Microbiology and Molecular Biology Reviews. 82
SUMMARY Cellular aggregation is an essential step in the formation of biofilms, which promote fungal survival and persistence in hosts. In many of the known yeast cell adhesion proteins, there are amino acid sequences predicted to form amyloid-like
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:6032-6038
Xanthochymol and garcinol, isoprenylated benzophenones purified from Garcinia xanthochymus fruits, showed multiple activities against Candida albicans biofilms. Both compounds effectively prevented emergence of fungal germ tubes and were also cytosta
Autor:
Peter N. Lipke, Stephen A. Klotz, Michael Bois, Cho X. J. Chan, Melissa C. Garcia-Sherman, Desmond N. Jackson, Caleen B. Ramsook
Publikováno v:
New journal of science
We tell of a journey that led to discovery of amyloids formed by yeast cell adhesins and their importance in biofilms and host immunity. We begin with the identification of the adhesin functional amyloid-forming sequences that mediate fiber formation
Autor:
David Alsteens, Yves F. Dufrêne, Peter N. Lipke, Audrey Beaussart, Sofiane El-Kirat-Chatel, Desmond N. Jackson
Publikováno v:
Nanoscale. 5:1105-1115
The advent of fungal pathogens that are resistant to the classic repertoire of antifungal drugs has increased the need for new therapeutic agents. A prominent example of such a novel compound is caspofungin, known to alter cell wall biogenesis by inh
Autor:
Peter N. Lipke, Yves F. Dufrêne, Cho X. J. Chan, Desmond N. Jackson, Sofiane El-Kirat-Chatel, Caleen B. Ramsook, Ivor G. Joseph
Publikováno v:
mSphere, Vol 1, Iss 4 (2016)
mSphere, Vol 1, Iss 4, p e00128-16 (2016)
mSphere
mSphere, Vol. 1, no.4, p. e00128-16 (2016)
MSphere
MSphere, American Society for Microbiology., 2016, 1 (4), ⟨10.1128/mSphere.00128-16⟩
mSphere, Vol 1, Iss 4, p e00128-16 (2016)
mSphere
mSphere, Vol. 1, no.4, p. e00128-16 (2016)
MSphere
MSphere, American Society for Microbiology., 2016, 1 (4), ⟨10.1128/mSphere.00128-16⟩
The Saccharomyces cerevisiae flocculins mediate the formation of cellular aggregates and biofilm-like mats, useful in clearing yeast from fermentations. An important property of fungal adhesion proteins, including flocculins, is the ability to form c
Publikováno v:
mBio, Vol 7, Iss 1, p e01815-15 (2016)
mBio
mBio, American Society for Microbiology, 2016, 7 (1), pp.296-303. ⟨10.1128/mBio.01815-15⟩
mBio, Vol 7, Iss 1 (2016)
mBio
mBio, American Society for Microbiology, 2016, 7 (1), pp.296-303. ⟨10.1128/mBio.01815-15⟩
mBio, Vol 7, Iss 1 (2016)
There is increasing evidence that many amyloids in living cells have physiological functions. On the surfaces of fungal cells, amyloid core sequences in adhesins can aggregate into 100- to 1,000-nm-wide patches to form high-avidity adhesion nanodomai
Publikováno v:
Planta Medica. 81
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0129152 (2015)
PLoS ONE, Vol 10, Iss 6, p e0129152 (2015)
Candida albicans adhesins have amyloid-forming sequences. In Als5p, these amyloid sequences cluster cell surface adhesins to create high avidity surface adhesion nanodomains. Such nanodomains form after force is applied to the cell surface by atomic