Výsledky vyhledávání - "Desmond Maitland"

Boosted saquinavir hard gel formulation exposure in HIV-infected subjects: ritonavir 100 mg once daily versus twice daily

Autor: Desmond Maitland, David Back, Anton Pozniak, Graeme Moyle, Andrew F. Hill, Brian Gazzard, Laura Dickinson, Marta Boffito, Mark T. Nelson, Carl Fletcher

Publikováno v: Journal of Antimicrobial Chemotherapy. 55:542-545

The amount of ritonavir needed to enhance saquinavir hard gel (hg) plasma concentrations is unclear. Reduced ritonavir dosing may help to reduce ritonavir-related side effects and costs. This study examined the pharmacokinetics of twice-daily saquina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f379db6dc0ee954557781d5aa06eb5
https://doi.org/10.1093/jac/dki043

Zobrazit plný text záznamu

Influence of atazanavir 200 mg on the intracellular and plasma pharmacokinetics of saquinavir and ritonavir 1600/100 mg administered once daily in HIV-infected patients

Autor: Jennifer Ford, Desmond Maitland, Anton Pozniak, Graeme Moyle, Saye Khoo, David Back, Marta Boffito, Brian Gazzard, Andrew Hill, Mark T. Nelson

Publikováno v: The Journal of antimicrobial chemotherapy. 58(5)

Objectives: To examine cellular and plasma concentrations of atazanavir when given in combination with saquinavir/ritonavir in HIV+ patients. Methods: Twelve HIV+ patients were receiving saquinavir/atazanavir/ritonavir 1600/200/100 mg once daily and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e943ecb79305073b7770d4e3397d9d
https://pubmed.ncbi.nlm.nih.gov/16984898

Zobrazit plný text záznamu

Pharmacokinetics of saquinavir hard-gel/ritonavir and atazanavir when combined once daily in HIV Type 1-infected individuals administered different atazanavir doses

Autor: Marta Boffito, Andrew F. Hill, Mark T. Nelson, Brian Gazzard, Graeme Moyle, David Back, Laura Dickinson, Carl Fletcher, Desmond Maitland, Anton Pozniak

Publikováno v: AIDS research and human retroviruses. 22(8)

The pharmacokinetics and short-term safety of atazanavir 150 and 200 mg, when coadministered with saquinavir/ritonavir 1600/100 mg once daily, were evaluated. On day 1, atazanavir 150 mg once daily, was added to saquinavir/ritonavir regimens and samp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3914ef4872a440e7da97b60c4a177e
https://pubmed.ncbi.nlm.nih.gov/16910830

Zobrazit plný text záznamu

Practical perspectives on the use of tipranavir in combination with other medications: lessons learned from pharmacokinetic studies

Autor: Marta Boffito, Desmond Maitland, Anton Pozniak

Publikováno v: Journal of clinical pharmacology. 46(2)

Drug-drug interactions are a major practical concern for physicians treating human immunodeficiency virus (HIV) because of the many medications that HIV-positive patients must take. Pharmacokinetic drug interactions can occur at different levels (abs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54cecef65fdb199fdfd36d80ae76cac4
https://pubmed.ncbi.nlm.nih.gov/16432264

Zobrazit plný text záznamu

Early virologic failure in HIV-1 infected subjects on didanosine/tenofovir/efavirenz: 12-week results from a randomized trial

Autor: Brian Gazzard, Graeme Moyle, James Hand, Desmond Maitland, Sundhiya Mandalia, Marta Boffito, Mark T. Nelson

Publikováno v: AIDS (London, England). 19(11)

To compare the safety and efficacy of two once-daily antiretroviral regimens containing lamivudine (3TC) or tenofovir disoproxil fumarate (TDF), each administered with didanosine (ddI) and efavirenz (EFV) as initial therapy to HIV-1-infected subjects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb282b937430b7e141115a0f8a20750
https://pubmed.ncbi.nlm.nih.gov/15990571

Zobrazit plný text záznamu

The pharmacokinetics of HIV protease inhibitor combinations

Autor: Marta Boffito, Desmond Maitland, Anton Pozniak, Yohan Samarasinghe

Publikováno v: Current opinion in infectious diseases. 18(1)

Purpose of review The clinical use of double-boosted protease inhibitor regimens has evolved recently. This strategy offers a number of unique benefits, including pharmacokinetic enhancement of two different protease inhibitors with low dose ritonavi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a509eab29556903b46986eacc0a276c
https://pubmed.ncbi.nlm.nih.gov/15647693

Zobrazit plný text záznamu

Akademický článek

Boosted saquinavir hard gel formulation exposure in HIV-infected subjects: ritonavir 100?mg once daily versus twice daily.

Autor: Marta Boffito, Desmond Maitland, Laura Dickinson, David Back, Andrew Hill, Carl Fletcher, Graeme Moyle, Mark Nelson, Brian Gazzard, Anton Pozniak

Publikováno v: Journal of Antimicrobial Chemotherapy (JAC); Apr2005, Vol. 55 Issue 4, p542-545, 4p

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání