Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Desmond J, Tobin"'
Autor:
Thierry Passeron, Brett King, Julien Seneschal, Martin Steinhoff, Ali Jabbari, Manabu Ohyama, Desmond J. Tobin, Simran Randhawa, Aaron Winkler, Jean-Baptiste Telliez, David Martin, Alexandre Lejeune
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Alopecia areata (AA) is an autoimmune disease that has a complex underlying immunopathogenesis characterized by nonscarring hair loss ranging from small bald patches to complete loss of scalp, face, and/or body hair. Although the etiopathogenesis of
Externí odkaz:
https://doaj.org/article/d8ae4e485ad24e7283726a80f1591e07
Autor:
Shahnawaz D. Jadeja, Desmond J. Tobin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Alopecia areata (AA) is a chronic, multifactorial, polygenic, and heterogeneous disorder affecting growing hair follicles in susceptible individuals, which results in a non-scarring and reversible hair loss with a highly unpredictable course. Despite
Externí odkaz:
https://doaj.org/article/99399c51266d415a87a5de7b575c762c
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The prevalence of Type 2 diabetes mellitus (T2DM) is escalating globally. Patients suffer from multiple complications including the development of chronic wounds that can lead to amputation. These wounds are characterised by an inflammatory
Externí odkaz:
https://doaj.org/article/04923bfd79f942aaa9dce1c01d951110
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cutaneous melanoma can be a most challenging neoplasm of high lethality, in part due to its extreme heterogeneity and characteristic aggressive and invasive nature. Indeed, its moniker ‘the great masquerader’ reflects that not all melanomas are c
Externí odkaz:
https://doaj.org/article/c0857677738a46c3934ddef35d783fd9
Autor:
Ayelet M Rosenberg, Shannon Rausser, Junting Ren, Eugene V Mosharov, Gabriel Sturm, R Todd Ogden, Purvi Patel, Rajesh Kumar Soni, Clay Lacefield, Desmond J Tobin, Ralf Paus, Martin Picard
Publikováno v:
eLife, Vol 10 (2021)
Background: Hair greying is a hallmark of aging generally believed to be irreversible and linked to psychological stress. Methods: Here, we develop an approach to profile hair pigmentation patterns (HPPs) along individual human hair shafts, producing
Externí odkaz:
https://doaj.org/article/35d0dd96c5ff465ebd75a8acc8547e1f
Autor:
Kaustubh Adhikari, Javier Mendoza-Revilla, Anood Sohail, Macarena Fuentes-Guajardo, Jodie Lampert, Juan Camilo Chacón-Duque, Malena Hurtado, Valeria Villegas, Vanessa Granja, Victor Acuña-Alonzo, Claudia Jaramillo, William Arias, Rodrigo Barquera Lozano, Paola Everardo, Jorge Gómez-Valdés, Hugo Villamil-Ramírez, Caio C. Silva de Cerqueira, Tábita Hunemeier, Virginia Ramallo, Lavinia Schuler-Faccini, Francisco M. Salzano, Rolando Gonzalez-José, Maria-Cátira Bortolini, Samuel Canizales-Quinteros, Carla Gallo, Giovanni Poletti, Gabriel Bedoya, Francisco Rothhammer, Desmond J. Tobin, Matteo Fumagalli, David Balding, Andrés Ruiz-Linares
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Pigmentation variation in humans is influenced by complex genetic architecture in different populations. Here, the authors perform a genome-wide association analysis involving > 6,000 Latin Americans for pigmentation of skin and eyes, and identify kn
Externí odkaz:
https://doaj.org/article/86c730a9ce5e412d8c65dc5984f7c306
Autor:
Shahnawaz D. Jadeja, Desmond J. Tobin
Publikováno v:
Kompass Dermatologie. 11:4-13
Alopecia areata (AA) ist eine chronische, multifaktorielle, polygene und heterogene Erkrankung, die wachsende Haarfollikel bei anfälligen Personen betrifft und zu einem nicht vernarbenden und reversiblen Haarausfall mit höchst unvorhersehbarem Verl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a5f8500e282f2b29181a5fe40ccbaba
https://doi.org/10.1159/000529035
https://doi.org/10.1159/000529035
Publikováno v:
Indian Journal of Dermatology, Vol 62, Iss 3, Pp 304-308 (2017)
Background: The incidence of self-reported premature hair graying (PHG) seems to be on the rise. PHG has a profound impact on the patient's quality of life. It remains an incompletely understood etiology with limited and modest treatment options. Aim
Externí odkaz:
https://doaj.org/article/6dd01a8a7be34b54aac27136f742fa40
Autor:
Stephanie M. Bollard, Cristina Casalou, Chia Yin Goh, Desmond J. Tobin, Pamela Kelly, Amanda McCann, Shirley M. Potter
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 475 (2020)
Malignant melanoma, one of the most aggressive human malignancies, is responsible for 80% of skin cancer deaths. Whilst early detection of disease progression or metastasis can improve patient survival, this remains a challenge due to the lack of rel
Externí odkaz:
https://doaj.org/article/59281281657c48bdb0bb8faa6fa7e0f4
Autor:
Kaustubh Adhikari, Tania Fontanil, Santiago Cal, Javier Mendoza-Revilla, Macarena Fuentes-Guajardo, Juan-Camilo Chacón-Duque, Farah Al-Saadi, Jeanette A. Johansson, Mirsha Quinto-Sanchez, Victor Acuña-Alonzo, Claudia Jaramillo, William Arias, Rodrigo Barquera Lozano, Gastón Macín Pérez, Jorge Gómez-Valdés, Hugo Villamil-Ramírez, Tábita Hunemeier, Virginia Ramallo, Caio C. Silva de Cerqueira, Malena Hurtado, Valeria Villegas, Vanessa Granja, Carla Gallo, Giovanni Poletti, Lavinia Schuler-Faccini, Francisco M. Salzano, Maria-Cátira Bortolini, Samuel Canizales-Quinteros, Francisco Rothhammer, Gabriel Bedoya, Rolando Gonzalez-José, Denis Headon, Carlos López-Otín, Desmond J. Tobin, David Balding, Andrés Ruiz-Linares
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
By examining Latin American individuals of mixed European, Native American and African ancestry, Adhikari et al. identify novel loci influencing various features of facial and scalp hair. The study also provides experimental evidence that one of the
Externí odkaz:
https://doaj.org/article/0f97fbb66079458f805844b2d61b335e