Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Desmond Heng"'
Autor:
Sie Huey Lee, Wei Xuan Yap, Chloe Qiu Zhen Jiang, Wei Xuan Ler, Jeanette Woon Pei Teo, Say Kong Ng, Desmond Heng
Publikováno v:
Journal of Drug Delivery Science and Technology. 76:103820
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb0795203a12a61ff11ba6d4b6fb2e92
https://doi.org/10.1016/j.jddst.2022.103820
https://doi.org/10.1016/j.jddst.2022.103820
Publikováno v:
Crystal Growth & Design. 19:3402-3409
This study reports a new technique for the manufacture of micron-sized, hollow crystals of a poorly water-soluble pharmaceutical compound, spironolactone, by a continuous and scalable antisolvent p...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1808d640ebfd67f1d5fe6c146f56d98
https://doi.org/10.1021/acs.cgd.9b00292
https://doi.org/10.1021/acs.cgd.9b00292
Publikováno v:
Journal of Aerosol Science. 95:104-117
This study investigated the effect of modifying the Aerolizer® inhaler design and material on bipolar charging of a powder aerosol. The modified inhalers included various grid configurations, mouthpiece lengths, air inlet sizes, and were also constr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::066ab412e434c09c0a767af9df3e105a
https://doi.org/10.1016/j.jaerosci.2016.02.003
https://doi.org/10.1016/j.jaerosci.2016.02.003
Publikováno v:
Journal of Pharmaceutical Sciences. 105:1501-1512
Respiratory lung infections due to multidrug-resistant (MDR) superbugs are on a global upsurge and have very grim clinical outcomes. Their MDR profile makes therapeutic options extremely limited. Although a highly toxic antibiotic, colistin, is favor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3b0aa94eb91404c70bd5c90cf74a8c
https://doi.org/10.1016/j.xphs.2016.02.007
https://doi.org/10.1016/j.xphs.2016.02.007
Publikováno v:
International Journal of Pharmaceutics. 572:118740
In respiratory and genetic disorders such as asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis and cystic fibrosis (CF), the lungs produce excess mucus, resulting in a thickened mass, which clogs up the airways and reduces airf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9fe6960c65ebbde15be7033dc399db
https://doi.org/10.1016/j.ijpharm.2019.118740
https://doi.org/10.1016/j.ijpharm.2019.118740
Autor:
Desmond Heng, Reginald B. H. Tan, Jeanette W. P. Teo, Hak-Kim Chan, Wai Kiong Ng, Yanli Zhao, Li Teng Tan, Sie Huey Lee
Publikováno v:
European Journal of Pharmaceutical Sciences. 70:37-44
Airway mucus hypersecretion is a common clinical feature of many severe respiratory diseases, and when complicated by a recalcitrant bacterial infection, the whole treatment regimen thereby becomes more challenging and protracted. The accumulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bf7f501398089ee843b259298c7320
https://doi.org/10.1016/j.ejps.2015.01.005
https://doi.org/10.1016/j.ejps.2015.01.005
Autor:
Wai Kiong Ng, Hak-Kim Chan, Desmond Heng, Reginald B. H. Tan, Jerry Y. Y. Heng, Sie Huey Lee, Jin W. Kwek, Santoso Adi
Publikováno v:
Journal of Aerosol Science. 65:77-87
A dry powder inhaler (DPI) is effective in treating respiratory diseases if it can deliver consistent and reliable drug dosage with each actuation. De-agglomeration and subsequent detachment of the drug from the carrier particles upon actuation depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a122044cab25cf72977f0949f9a802
https://doi.org/10.1016/j.jaerosci.2013.07.011
https://doi.org/10.1016/j.jaerosci.2013.07.011
Autor:
Wai Kiong Ng, Hak-Kim Chan, Jeanette W. P. Teo, Desmond Heng, Reginald B. H. Tan, Sie Huey Lee
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 83:275-284
In combination antimicrobial therapy, the desired outcome is to broaden the antimicrobial spectrum and to achieve a possible synergistic effect. However, adverse antagonistic species may also emerge from such combinations, leading to treatment failur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049b514006b7f54be0d2a15898f427b6
https://doi.org/10.1016/j.ejpb.2012.09.002
https://doi.org/10.1016/j.ejpb.2012.09.002
Publikováno v:
Powder Technology. 226:253-260
In dry powder inhaler therapy, it is often highly desirable to maximise the fine particle fraction (FPF) while reducing the throat and inhaler retention. While there are a number of factors affecting aerosolization, there is at present no combinatori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13aabbd635b3c9f042b8a41c1cd6e359
https://doi.org/10.1016/j.powtec.2012.04.056
https://doi.org/10.1016/j.powtec.2012.04.056
Publikováno v:
International Journal of Pharmaceutics. 403:192-200
There has been an increasing interest in the development of protein nanotherapeutics for diseases such as cancer, diabetes and asthma. Spray drying with prior micro mixing is commonly used to obtain these powders. However, the separation and collecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eab9ea09398f9c0edf6fa379e45faa9
https://doi.org/10.1016/j.ijpharm.2010.10.012
https://doi.org/10.1016/j.ijpharm.2010.10.012