Zobrazeno 1 - 10
of 398
pro vyhledávání: '"Desmoglein-2"'
Autor:
Wendy E. Heywood, Jon Searle, Richard Collis, Ivan Doykov, Michael Ashworth, Neil Sebire, Andrew Bamber, Mathias Gautel, Simon Eaton, Caroline J. Coats, Perry M. Elliott, Kevin Mills
Publikováno v:
Life, Vol 14, Iss 8, p 970 (2024)
Proteomics studies often explore phenotypic differences between whole organs and systems. Within the heart, more subtle variation exists. To date, differences in the underlying proteome are only described between whole cardiac chambers. This study, u
Externí odkaz:
https://doaj.org/article/c8a6dfe6be694246b433b3a2ecda8baf
Autor:
Kay K. Myo Min, Charlie B. Ffrench, Barbara J. McClure, Michael Ortiz, Emma L. Dorward, Michael S. Samuel, Lisa M. Ebert, Mỹ G. Mahoney, Claudine S. Bonder
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Desmoglein-2 (DSG2) is a calcium-binding single pass transmembrane glycoprotein and a member of the large cadherin family. Until recently, DSG2 was thought to only function as a cell adhesion protein embedded within desmosome junctions designed to en
Externí odkaz:
https://doaj.org/article/f4ce993d01f14417bead657be6745a94
Desmoglein‐2 expression is an independent predictor of poor prognosis patients with multiple myeloma
Autor:
Lisa M. Ebert, Kate Vandyke, M. Zahied Johan, Mark DeNichilo, Lih Y. Tan, Kay K. Myo Min, Benjamin M. Weimann, Brenton W. Ebert, Stuart M. Pitson, Andrew C. W. Zannettino, Craig T. Wallington‐Beddoe, Claudine S. Bonder
Publikováno v:
Molecular Oncology, Vol 16, Iss 6, Pp 1221-1240 (2022)
Multiple myeloma (MM) is the second most common haematological malignancy and is an incurable disease of neoplastic plasma cells (PC). Newly diagnosed MM patients currently undergo lengthy genetic testing to match chromosomal mutations with the most
Externí odkaz:
https://doaj.org/article/3c6fe6a110d5445e84fcd27cd4ff16e5
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background High temperature requirement A (HtrA) is an active serine protease secreted by the group-I carcinogen Helicobacter pylori (H. pylori). The human cell adhesion protein and tumor suppressor E-cadherin (hCdh1) expressed on the surfac
Externí odkaz:
https://doaj.org/article/16a0e2b933244d749b94d26a156c2a11
Akademický článek
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Akademický článek
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Publikováno v:
International Medical Case Reports Journal, Vol Volume 14, Pp 307-313 (2021)
Rui Huang,1,* YinHua Luo,2,* Jingbo Zhao,1 Ke Su,1 YuHua Lei,1 Yuanhong Li1 1Cardiovascular Disease Center, Central Hospital of Tujia and Miao Autonomous Prefecture, Enshi Clinical College of Wuhan University, Enshi Prefecture, 445000, Hubei Province
Externí odkaz:
https://doaj.org/article/c26e04d071d44c3b9a325c74d5ba7410
Autor:
Shuhang Qin, Yuandong Liao, Qiqiao Du, Wei Wang, Jiaming Huang, Pan Liu, Chunliang Shang, Tianyu Liu, Meng Xia, Shuzhong Yao
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background The pathogenesis and developmental mechanism of early-stage (FIGO 2009 IA2-IIA2) cervical cancer (CC) remain unclear. Seeking novel molecular biomarkers based on The Cancer Genome Atlas (TCGA) will facilitate the understanding of
Externí odkaz:
https://doaj.org/article/ae960597de614206b9a82de3a2f36586
Autor:
Bing‐Xia Zhou, Yan Li
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 36, Iss 5, Pp 336-343 (2020)
Abstract Desmoglein‐2 (DSG2) is an integral component of desmosomes, maintaining cell‐cell adhension in multiple cancers. It has been well studied in epithelial cells, cardiomyocytes and primary prostate cancer, colon cancer, skin squamous cell c
Externí odkaz:
https://doaj.org/article/c244c09ab75c4625817be199601d653e
Publikováno v:
Cells, Vol 11, Iss 20, p 3184 (2022)
Background: Arrhythmogenic cardiomyopathy (ACM) is a genetic heart muscle disease characterized by progressive fibro-fatty replacement of cardiac myocytes. Up to now, the existing therapeutic modalities for ACM are mostly palliative. About 50% of ACM
Externí odkaz:
https://doaj.org/article/27460e443eab4bfeace90358f6919d13