Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Desislava Nesheva"'
Autor:
Sena Karachanak-Yankova, Dimitar Serbezov, Marta Mihaylova, Dragomira Nikolova, Lubomir Balabanski, Vera Damyanova, Olga Antonova, Rada Staneva, Mihail Ganev, Victoria Spasova, Blaga Rukova, Desislava Nesheva, Slavica Josifovska, Mikaela Stancheva, Diana Belejanska, Mariya Petrova, Shima Mehrabian, Latchezar Traykov, Savina Hadjidekova, Draga Toncheva
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 37, Iss 1, Pp 74-78 (2023)
AbstractIn an effort to better understand the complex genetic background of Alzheimer’s disease (AD) we performed high-coverage whole-exome sequencing of a DNA pool assembled of 66 Bulgarian AD patients. We focused our analysis on genes demonstrate
Externí odkaz:
https://doaj.org/article/9f16b95efe9046c1b5858050d17509bf
Autor:
Lubomir Balabanski, Dimitar Serbezov, Maya Atanasoska, Sena Karachanak-Yankova, Savina Hadjidekova, Dragomira Nikolova, Olga Boyanova, Rada Staneva, Radoslava Vazharova, Marta Mihailova, Vera Damyanova, Desislava Nesheva, Diana Belejanska, Shima Mehrabian, Lachezar Traykov, Draga Toncheva
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 35, Iss 1, Pp 1256-1262 (2021)
Contemporary genetic methods have not yet solved the ‘missing heritability’ problem of complex diseases such as Alzheimer’s disease (AD). The impact of rare or less common variation on human complex diseases and traits remains to date barely in
Externí odkaz:
https://doaj.org/article/69eab2e91aa343ae9dd277605a11f652
Autor:
Olga Antonova, Blaga Rukova, Boris Mladenov, Simeon Rangelov, Zora Hammoudeh, Desislava Nesheva, Rada Staneva, Viktoria Spasova, Evgeni Grigorov, Savina Hadjidekova, Chavdar Slavov, Draga Toncheva
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 34, Iss 1, Pp 506-514 (2020)
Many bladder cancer (BC) patients with early disease are asymptomatic and diagnosed at advanced stage when the therapeutic options are limited. This necessitates the development of reliable predictive molecular biomarkers that will ensure a positive
Externí odkaz:
https://doaj.org/article/3e62798fdd4d4d4db5aacf6122e602ed
Autor:
Mihail Ganev, Lubomir Balabanski, Dimitar Serbezov, Sena Karachanak-Yankova, Radoslava Vazharova, Desislava Nesheva, Zora Hammoudeh, Dragomira Nikolova, Olga Antonova, Rada Staneva, Marta Mihaylova, Vera Damyanova, Savina Hadjidekova, Draga Toncheva
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 1757-1765 (2019)
Coronary heart disease (CHD) is a major cause of mortality and morbidity in Europe. CHD is usually caused by atherosclerosis. Despite extensive studies that have identified a large number of genetic variants, strong evidence of association with CHD a
Externí odkaz:
https://doaj.org/article/bb04476f30124e098a0c0d56ae2bf45c
Autor:
Lubomir Balabanski MSc, Dimitar Serbezov PhD, Dragomira Nikolova PhD, Olga Antonova PhD, Desislava Nesheva PhD, Zora Hammoudeh PhD, Radoslava Vazharova PhD, Sena Karachanak-Yankova PhD, Rada Staneva PhD, Marta Mihaylova PhD, Vera Damyanova PhD, Savina Hadjidekova PhD, Draga Toncheva PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 19 (2020)
Objectives: The aim of the present study was to evaluate the clinical relevance of mutations in tumor suppressor genes using whole-exome sequencing data from centenarians and young healthy individuals. Methods: Two pools, one of centenarians and one
Externí odkaz:
https://doaj.org/article/0fe8fad5d789431cae223b2e68b77e63
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0233666 (2020)
Mitochondrial DNA variants associated with diseases are widely studied in contemporary populations, but their prevalence has not yet been investigated in ancient populations. The publicly available AmtDB database contains 1443 ancient mtDNA Eurasian
Externí odkaz:
https://doaj.org/article/bf2dbf030ae84faababf468e4180dbc2
Autor:
Shima Mehrabian, Håkan Thonberg, Margarita Raycheva, Lena Lilius, Katya Stoyanova, Charlotte Forsell, Lena Cavallin, Desislava Nesheva, Eric Westman, Draga Toncheva, Latchezar Traykov, Bengt Winblad, Caroline Graff
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208383 (2018)
BACKGROUND:The GGGGCC repeat expansion in the C9orf72 gene was recently identified as a major cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in several European populations. The objective of this study was to determine
Externí odkaz:
https://doaj.org/article/add95637bef840a3b4f9c5de3c500521
Autor:
Sena Karachanak, Viola Grugni, Simona Fornarino, Desislava Nesheva, Nadia Al-Zahery, Vincenza Battaglia, Valeria Carossa, Yordan Yordanov, Antonio Torroni, Angel S Galabov, Draga Toncheva, Ornella Semino
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e56779 (2013)
To better define the structure and origin of the Bulgarian paternal gene pool, we have examined the Y-chromosome variation in 808 Bulgarian males. The analysis was performed by high-resolution genotyping of biallelic markers and by analyzing the STR
Externí odkaz:
https://doaj.org/article/5e22306e87604d948684e910c0aca0c3
Autor:
Sena Karachanak-Yankova, Draga Toncheva, Marta Mihailova, Olga Boyanova, Dimitar Serbezov, Diana Belejanska, Lubomir Balabanski, Desislava Nesheva, Shima Mehrabian, Rada Staneva, Maya Atanasoska, Dragomira Nikolova, Vera Damyanova, Lachezar Traykov, Radoslava Vazharova, Savina Hadjidekova
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 35, Iss 1, Pp 1256-1262 (2021)
Contemporary genetic methods have not yet solved the ‘missing heritability’ problem of complex diseases such as Alzheimer’s disease (AD). The impact of rare or less common variation on human complex diseases and traits remains to date barely in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158130dacb4a2453fde11b47b567b8ba
https://doaj.org/article/69eab2e91aa343ae9dd277605a11f652
https://doaj.org/article/69eab2e91aa343ae9dd277605a11f652
Autor:
Petar Kalcev, Chiara Vergata, Rada Staneva, Martina Lari, Desislava Nesheva, Draga Toncheva, David Caramelli, Yordan Yordanov, Diana Dimitrova, Savina Hadjidekova, Olga Antonova, Alessandra Modi, Stefania Vai, Sena Karachanak-Yankova, Donata Luiselli, Angel S. Galabov, Stefania Sarno, Elena Pilli
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
One of the best documented Indo-European civilizations that inhabited Bulgaria is the Thracians, who lasted for more than five millennia and whose origin and relationships with other past and present-day populations are debated among researchers. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfdf130a19e819bf99ce3f3971fe18aa
http://link.springer.com/article/10.1038/s41598-019-41945-0
http://link.springer.com/article/10.1038/s41598-019-41945-0