Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Desislava Met Doycheva"'
Autor:
Shucai Xie, Xili Jiang, Desislava Met Doycheva, Hui Shi, Peng Jin, Ling Gao, Rui Liu, Jie Xiao, Xiao Hu, Jiping Tang, Lina Zhang, John H. Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-15 (2021)
Abstract Background Hypoxic–ischemic encephalopathy (HIE) is a severe anoxic brain injury that leads to premature mortality or long-term disabilities in infants. Neuroinflammation is a vital contributor to the pathogenic cascade post-HIE and a medi
Externí odkaz:
https://doaj.org/article/d3eded81a55841ee914704588c636fc3
Autor:
Ningbo Xu, Xifeng Li, Jun Weng, Chunhua Wei, Zhenyan He, Desislava Met Doycheva, Cameron Lenahan, Wenhui Tang, Jian Zhou, Yanchao Liu, Qiang Xu, Yahong Liu, Xuying He, Jiping Tang, John H. Zhang, Chuanzhi Duan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adiponectin (APN), a fat-derived plasma hormone, is a classic anti-inflammatory agent. Multiple studies have demonstrated the beneficial role of APN in acute brain injury, but the effect of APN in germinal matrix hemorrhage (GMH) is unclear, and the
Externí odkaz:
https://doaj.org/article/b1233ba1c91543cfb90e53d879fe9062
Autor:
Shufeng Yu, Desislava Met Doycheva, Marcin Gamdzyk, Yijun Yang, Cameron Lenahan, Gaigai Li, Dujuan Li, Lifei Lian, Jiping Tang, Jun Lu, John H. Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-20 (2021)
Abstract Background Microglia-mediated neuroinflammation plays a crucial role in the pathogenesis of hypoxic-ischemic (HI)-induced brain injury. Activation of melanocortin-1 receptor (MC1R) has been shown to exert anti-inflammatory and neuroprotectiv
Externí odkaz:
https://doaj.org/article/b354140e710d4c65a6093bda7180e996
Rh-CSF1 attenuates neuroinflammation via the CSF1R/PLCG2/PKCε pathway in a rat model of neonatal HIE
Autor:
Xiao Hu, Shirong Li, Desislava Met Doycheva, Lei Huang, Cameron Lenahan, Rui Liu, Juan Huang, Shucai Xie, Jiping Tang, Gang Zuo, John H. Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Hypoxic-ischemic encephalopathy (HIE) is a life-threatening cerebrovascular disease. Neuroinflammation plays an important role in the pathogenesis of HIE, in which microglia are key cellular mediators in the regulation of neuroinf
Externí odkaz:
https://doaj.org/article/1d24f5209391424bb43084180cff0ecb
Autor:
Juan Huang, Weitian Lu, Desislava Met Doycheva, Marcin Gamdzyk, Xiao Hu, Rui Liu, John H. Zhang, Jiping Tang
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Inhibition of inositol-requiring enzyme-1 alpha (IRE1α), one of the sensor signaling proteins associated with endoplasmic reticulum (ER) stress, has been shown to alleviate brain injury and improve neurological behavior in a neon
Externí odkaz:
https://doaj.org/article/cfc07738a13542d88036f0108ded558c
Autor:
Jing Peng, Min Wu, Desislava Met Doycheva, Yi He, Qiongzhen Huang, Wei Chen, Nathanael Matei, Jun Ding, Kangning Chen, Ningbo Xu, Zhenhua Zhou
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Carotid artery dissection (CAD) is the leading cause of ischemic stroke in young patients; however, the etiology and pathophysiology of CAD remain largely unknown. In our study, two types of dissections (length × width: 1.5 cm × 1/3 circumference o
Externí odkaz:
https://doaj.org/article/984550645a624a0886d3f9499c1f3680
Publikováno v:
Neurobiology of Disease, Vol 95, Iss , Pp 111-121 (2016)
Objective: Hypoxic ischemic (HI) encephalopathy remains the leading cause of perinatal brain injury resulting in long term disabilities. Stabilization of blood brain barrier (BBB) after HI is an important target, therefore, in this study we aim to de
Externí odkaz:
https://doaj.org/article/1f97f556c2214ec586599d83a79bfc06
Autor:
Shufeng Yu, Desislava Met Doycheva, Marcin Gamdzyk, Yuanyuan Gao, Yong Guo, Zachary D. Travis, Jiping Tang, Wen-Xiong Chen, John H. Zhang
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2022 (2022)
Oxidative Medicine and Cellular Longevity, Vol 2022 (2022)
Neuronal apoptosis induced by oxidative stress plays an important role in the pathogenesis and progression of hypoxic-ischemic encephalopathy (HIE). Previous studies reported that activation of melanocortin-1 receptor (MC1R) exerts antioxidative stre