Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Desiree, Kunkel"'
Autor:
Gerardina Gallaccio, Meng Wang, Stephan Schlickeiser, Desiree Kunkel, Chotima Böttcher, Camila Fernández-Zapata
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103038- (2024)
Summary: Phenotypic and compositional changes of immune cells in cerebrospinal fluid (CSF) can be used as biomarkers to help diagnose and track disease activity for neuroinflammatory and neurodegenerative diseases. Here, we present a workflow to perf
Externí odkaz:
https://doaj.org/article/1324c7d061b341a38ebd136fbc3b6eaa
Autor:
Meng Wang, Adeline Dehlinger, Camila Fernández Zapata, Maya Golan, Gerardina Gallaccio, Leif E. Sander, Stephan Schlickeiser, Desiree Kunkel, Tanja Schmitz-Hübsch, Birgit Sawitzki, Arnon Karni, Julian Braun, Lucie Loyal, Andreas Thiel, Judith Bellmann-Strobl, Friedemann Paul, Lil Meyer-Arndt, Chotima Böttcher
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Disease-modifying therapies (DMTs) are widely used in neuroimmunological diseases such as multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). Although these treatments are known to predispose patients to infections an
Externí odkaz:
https://doaj.org/article/d27cf0ad534841919c3c0921b0dd34df
Autor:
Camila Fernández Zapata, Ginevra Giacomello, Eike J. Spruth, Jinte Middeldorp, Gerardina Gallaccio, Adeline Dehlinger, Claudia Dames, Julia K. H. Leman, Roland E. van Dijk, Andreas Meisel, Stephan Schlickeiser, Desiree Kunkel, Elly M. Hol, Friedemann Paul, Maria Kristina Parr, Josef Priller, Chotima Böttcher
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Multiple state-of-the-art analyses of immune cells in 117 blood, 117 cerebrospinal fluid, 13 choroid plexus and 13 brain parenchyma samples reveal differential characteristics of immune cells in different body compartments and different diseases.
Externí odkaz:
https://doaj.org/article/0d65d08cd80c43d8a1abeff32711616d
Autor:
Camila Fernandez Zapata, Ginevra Giacomello, Eike Spruth, Jinte Middeldorp, Gerardina Gallaccio, Adeline Dehlinger, Claudia Dames, Roland E Van Dijk, Andreas Meisel, Stephan Schlickeiser, Desiree Kunkel, Elly Hol, Friedemann Paul, Maria Parr, Josef Priller, Chotima Böttcher
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S275-S276 (2023)
Externí odkaz:
https://doaj.org/article/5677e88b77ab4a0f9d4df05e30ac7650
Autor:
Christos Nikolaou, Kerstin Muehle, Stephan Schlickeiser, Alberto Sada Japp, Nadine Matzmohr, Desiree Kunkel, Marco Frentsch, Andreas Thiel
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-19 (2021)
Abstract Background Immune ageing is a result of repetitive microbial challenges along with cell intrinsic or systemic changes occurring during ageing. Mice under ‘specific-pathogen-free’ (SPF) conditions are frequently used to assess immune agei
Externí odkaz:
https://doaj.org/article/8d32dcc8dc104467bb34b78befd1178c
Autor:
Chotima Böttcher, Marlijn van der Poel, Camila Fernández-Zapata, Stephan Schlickeiser, Julia K. H. Leman, Cheng-Chih Hsiao, Mark R. Mizee, Adelia, Maria C. J. Vincenten, Desiree Kunkel, Inge Huitinga, Jörg Hamann, Josef Priller
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-18 (2020)
Abstract Myeloid cells contribute to inflammation and demyelination in the early stages of multiple sclerosis (MS), but it is still unclear to what extent these cells are involved in active lesion formation in progressive MS (PMS). Here, we have harn
Externí odkaz:
https://doaj.org/article/006079524a1148c4a991c13d07a96ce0
Autor:
Jörn F. Ziegler, Chotima Böttcher, Marilena Letizia, Cansu Yerinde, Hao Wu, Inka Freise, Yasmina Rodriguez-Sillke, Ani K. Stoyanova, Martin E. Kreis, Patrick Asbach, Desiree Kunkel, Josef Priller, Ioannis Anagnostopoulos, Anja A. Kühl, Konstanze Miehle, Michael Stumvoll, Florian Tran, Broder Fredrich, Michael Forster, Andre Franke, Christian Bojarski, Rainer Glauben, Britt-Sabina Löscher, Britta Siegmund, Carl Weidinger
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The adipokine leptin modulates intestinal inflammation in mice. Here the authors describe a patient with inflammatory bowel disease and lipodystrophy, providing evidence that leptin aggravates intestinal inflammation with proinflammatory effects on l
Externí odkaz:
https://doaj.org/article/930d669ed7b944499b66502ad66aa5e6
Autor:
Raphael Brandt, Thomas Sell, Mareen Lüthen, Florian Uhlitz, Bertram Klinger, Pamela Riemer, Claudia Giesecke-Thiel, Silvia Schulze, Ismail Amr El-Shimy, Desiree Kunkel, Beatrix Fauler, Thorsten Mielke, Norbert Mages, Bernhard G. Herrmann, Christine Sers, Nils Blüthgen, Markus Morkel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
KRASG12V and BRAFV600E are oncogenic mutations that activate ERK signalling. Here, the authors use single cell analysis in intestinal organoids and show that BRAFV600E activates ERK in all intestinal cell types, while KRASG12V induces ERK activation
Externí odkaz:
https://doaj.org/article/4dc8feb67d344b21b71aced69388d1f8
Autor:
Christos Nikolaou, Kerstin Muehle, Stephan Schlickeiser, Alberto Sada Japp, Nadine Matzmohr, Desiree Kunkel, Marco Frentsch, Andreas Thiel
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/e41d050784bf48ae96cfdbe1dc51cf05
Autor:
Chotima, Böttcher, Stephan, Schlickeiser, Marjolein A M, Sneeboer, Desiree, Kunkel, Anniki, Knop, Evdokia, Paza, Pawel, Fidzinski, Larissa, Kraus, Gijsje J L, Snijders, René S, Kahn, Axel R, Schulz, Henrik E, Mei, Elly M, Hol, Britta, Siegmund, Rainer, Glauben, Eike J, Spruth, Lot D, de Witte, Josef, Priller
Publikováno v:
Epilepsy Currents
Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry Böttcher C, Schlickeiser S, Sneeboer MAM, et al. Nat Neurosci. 2019;22(1):78-90.Microglia, the specialized innate immune cells of the central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09daca5b1cc1a094ca2c42c06425cfec
https://pubmed.ncbi.nlm.nih.gov/31032668
https://pubmed.ncbi.nlm.nih.gov/31032668