Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Desire Ngoga"'
Glioblastoma Multiforme –(GBM) are infiltrative, impossible to resect totally and consequently recur almost always at the borders of the resection margin. There is no established chemotherapy regimen available to patients who recur. Systemic treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f87a1004aca912f460caee52424481
https://europepmc.org/articles/PMC5358608/
https://europepmc.org/articles/PMC5358608/
Publikováno v:
Neuro-Oncology. 20:i1-i1
Direct drug delivery to a brain tumours offers the surety of access, together with the potential to realise at least therapeutic concentrations. With previously used systemic drugs toxicity and removal mechanisms are avoided. With new formulations dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc33e4fd5941d66bbe54ab0806718dc
https://doi.org/10.1093/neuonc/nox237.000
https://doi.org/10.1093/neuonc/nox237.000
Autor:
Daniel A. Tennant, Kate E.R. Hollinshead, Yunpeng Liu, Desire Ngoga, Marina Vabistsevits, Garth Cruickshank, Katrin Lamszus, Weiqi Chen, Jean-Baptiste Cazier, Shan He, Daniel Swan
Gliomas are the most common type of brain tumour, yet their biology is still poorly understood. Despite recent advances in our understanding of low grade gliomas through the discovery of mutations in isocitrate dehydrogenase (IDH) enzymes 1&2 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7622f3d4e38df75990aa54d768433cb
https://europepmc.org/articles/PMC4638826/
https://europepmc.org/articles/PMC4638826/
Publikováno v:
Europe PubMed Central
INTRODUCTION: Low socioeconomic status is associated with increased frequency of chronic conditions, a higher frequency of mental health illness, greater use of primary care and hospital services and a lower relative cancer survival for some of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d3a35f889dd70ddddd92b1182dca49
https://europepmc.org/articles/PMC4200967/
https://europepmc.org/articles/PMC4200967/
Autor:
C. Mauffrey, Desire Ngoga
Publikováno v:
European Journal of Orthopaedic Surgery & Traumatology. 17:321-323
Diaphragmatic rupture occurs in 25% of blunt thoracic and abdominal trauma and is an important diagnosis to consider in the trauma setting. We report a case of a 45-year-old female driver admitted with chest and abdominal trauma following a road traf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc8641d98fdd747f3f07cbd9f6735839
https://doi.org/10.1007/s00590-006-0160-6
https://doi.org/10.1007/s00590-006-0160-6
Autor:
Garth Cruickshank, John C. Vickerman, Stuart Green, J. Doran, J. Hardie, C. Wojnecki, A. Chopra, M. Chester, Steven Ford, Allah Detta, Nicholas D. James, R. Braithwaite, G. Croswell, N. Graham, Nicholas P. Lockyer, Gavin Halbert, T. M. T. Sheehan, Desire Ngoga, R. Sugar, Alan V. Boddy, Heidi Steinfeldt, Mary Elliot, Z. Ghani
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 67(7-8)
This paper describes results to-date from a human pharmacokinetic study which began recruitment in December 2007. Results are presented for a single patient recruited in December 2007. A second patient was recruited in July 2008 but detailed data are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288ecaef7ad6f15846cf6064c564f8af
https://pubmed.ncbi.nlm.nih.gov/19447633
https://pubmed.ncbi.nlm.nih.gov/19447633
Publikováno v:
Neuro-Oncology. 17:v11.1-v11
BACKGROUND: Chemotherapy for brain tumours has been limited because of difficulty in achieving exposure to the tumour without systemic toxicity. Parenteral Irinotecan despite activity against glioma has an uncertain entry into the brain that has ques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea7fb2f9dc7d65469b8c2e492f38fc1
https://doi.org/10.1093/neuonc/nov205.05
https://doi.org/10.1093/neuonc/nov205.05
Autor:
Steven Ford, John F. Thompson, T. M. T. Sheehan, Mark A. Hill, Moira A. Elliott, Nicholas P. Lockyer, N. Graham, A. King, Garth Cruickshank, Alan V. Boddy, B. Phoenix, G. Croswell, Gavin Halbert, A. J. Mill, J. Doran, C. Wojnecki, John C. Vickerman, S. Green, Z. Ghani, Bleddyn Jones, Nicholas D. James, Desire Ngoga, M.W. Charles, A. Detta
Publikováno v:
Clinical Oncology. 23:S23-S24
This paper will review progress on two aspects of the Birmingham BNCT project. Firstly on evaluation of the effects of high and low LET radiations when delivered simultaneously, and secondly on attempts to optimise delivery of the boron carrier compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d0a019a0243861a8e22874a41fe6d3d
https://doi.org/10.1016/j.clon.2011.01.378
https://doi.org/10.1016/j.clon.2011.01.378
Autor:
Ben Phoenix, Desire Ngoga, Zahir Ghani, Nicholas P. Lockyer, Garth Cruickshank, S. Green, A. Detta
Publikováno v:
Neuro-Oncology. 16:v82-v82
BNCT is a biologically targeted radiotherapy where preferential boron uptake interacts with a neutron beam in cancerous cells causing irreparable alpha DNA damage. This requires the delivery of at least 30 parts per million (ppm) of 10B into tumour t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54146a4fca8a508bb9af3f597db7121d
https://doi.org/10.1093/neuonc/nou255.14
https://doi.org/10.1093/neuonc/nou255.14
Autor:
A. Detta, Nicholas P. Lockyer, Desire Ngoga, G.C. Cruickshank, B. Phoenix, Z. Ghani, S. Green
Publikováno v:
Neuro-Oncology. 16:ii67-ii67
BNCT is a biologically targeted form of enhanced cellular radiotherapy where preferential accumulation of boron in the cancerous as opposed to adjacent normal cells is able to interact with incident neutrons to cause irreversible alpha particle DNA d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d237c7ba7d35ac4a2627a4ffcff8d264
https://doi.org/10.1093/neuonc/nou174.255
https://doi.org/10.1093/neuonc/nou174.255