Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Desiré García-Pichardo"'
Autor:
Pedro Ortega, Desiré García-Pichardo, Marta San Martin-Alonso, Ana G. Rondón, Belén Gómez-González, Andrés Aguilera
Publikováno v:
Microbial Cell, Vol 7, Iss 7, Pp 190-198 (2020)
The stability and function of eukaryotic genomes is closely linked to histones and to chromatin structure. The state of the chromatin not only affects the probability of DNA to undergo damage but also DNA repair. DNA damage can result in genetic alte
Externí odkaz:
https://doaj.org/article/6e1436c1a9dd4bfd92467197dc41a687
Publikováno v:
Gowthaman, U, García-pichardo, D, Jin, Y, Schwarz, I & Marquardt, S 2020, ' DNA Processing in the Context of Noncoding Transcription ', Trends in Biochemical Sciences, vol. 45, no. 12, pp. 1009-1021 . https://doi.org/10.1016/j.tibs.2020.07.009
Trends in Biochemical Sciences
Trends in Biochemical Sciences
RNA polymerase (RNAP)II frequently transcribes non-protein-coding DNA sequences in eukaryotic genomes into long noncoding RNA (lncRNA). Distinct molecular mechanisms linked to the position of lncRNA relative to the coding gene illustrate how noncodin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47f1f7ca15d56ab519bc66a25f5a36c
https://doi.org/10.1016/j.tibs.2020.07.009
https://doi.org/10.1016/j.tibs.2020.07.009
Autor:
Marta San Martin-Alonso, Ana G. Rondón, Desiré García-Pichardo, Belén Gómez-González, Pedro A. Ortega, Andrés Aguilera
Publikováno v:
Microbial Cell
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Microbial Cell, Vol 7, Iss 7, Pp 190-198 (2020)
idUS. Depósito de Investigación de la Universidad de Sevilla
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Microbial Cell, Vol 7, Iss 7, Pp 190-198 (2020)
idUS. Depósito de Investigación de la Universidad de Sevilla
The stability and function of eukaryotic genomes is closely linked to histones and to chromatin structure. The state of the chromatin not only affects the probability of DNA to undergo damage but also DNA repair. DNA damage can result in genetic alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29a9c4581c31e652133335f1755be6d
http://europepmc.org/articles/PMC7328676
http://europepmc.org/articles/PMC7328676
Autor:
Sebastian Marquardt, Tineke L. Lenstra, Desiré García-Pichardo, Niels A. Müller, Heta P. Patel, Isabel Schwarz, Maxim Ivanov, Uthra Gowthaman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339547d6db1ee8940912e3577256980a
https://doi.org/10.15252/rc.2022873503
https://doi.org/10.15252/rc.2022873503
Autor:
Heta P. Patel, Niels A. Müller, Maxim Ivanov, Desiré García-Pichardo, Sebastian Marquardt, Tineke L. Lenstra, Isabel Schwarz, Uthra Gowthaman
Nucleosome-depleted regions (NDRs) at gene promoters support initiation of RNA Polymerase II transcription. Interestingly, transcription often initiates in both directions, resulting in an mRNA, and a divergent non-coding (DNC) transcript with an unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f21badd18835147092262aed4cadc28
https://doi.org/10.1101/2021.04.06.438606
https://doi.org/10.1101/2021.04.06.438606
RNA polymerase II (RNAPII) frequently transcribes non-protein coding DNA sequences in eukaryotic genomes into long non-coding RNA (lncRNA). Here, we focus on the impact of the act of lncRNA transcription on nearby functional DNA units. Distinct molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cec0afdf84e7e665a2a9d6e0854d425
https://doi.org/10.20944/preprints202007.0744.v1
https://doi.org/10.20944/preprints202007.0744.v1
Autor:
Desiré García-Pichardo, Juan C. Cañas, Belén Gómez-González, María L. García-Rubio, Andrés Aguilera, Ana G. Rondón
Publikováno v:
Molecular Cell
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS. Depósito de Investigación de la Universidad de Sevilla
R loops have positive physiological roles, but they can also be deleterious by causing genome instability, and the mechanisms for this are unknown. Here we identified yeast histone H3 and H4 mutations that facilitate R loops but do not cause instabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20a94c0225e2c571e84d989f0995532
https://hdl.handle.net/10668/11265
https://hdl.handle.net/10668/11265
Autor:
Heta P. Patel, Niels A. Müller, Tineke L. Lenstra, Isabel Schwarz, Uthra Gowthaman, Desiré García-Pichardo, Sebastian Marquardt, Maxim Ivanov
Publikováno v:
Gowthaman, U, Ivanov, M, Schwarz, I, Patel, H P, Müller, N A, Garcia-Pichardo, D, Lenstra, T L & Marquardt, S 2021, ' The Hda1 histone deacetylase limits divergent non-coding transcription and restricts transcription initiation frequency ', EMBO Journal, vol. 40, no. 23, 108903 . https://doi.org/10.15252/embj.2021108903
The EMBO Journal
The EMBO Journal
Nucleosome‐depleted regions (NDRs) at gene promoters support initiation of RNA polymerase II transcription. Interestingly, transcription often initiates in both directions, resulting in an mRNA and a divergent non‐coding (DNC) transcript of uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c96ba74981abd9fcaaf8a3b199776e4