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pro vyhledávání: '"Desikan, Rajat"'
The COVID-19 pandemic has severely impacted health systems and economies worldwide. Significant global efforts are therefore ongoing to improve vaccine efficacies, optimize vaccine deployment, and develop new antiviral therapies to combat the pandemi
Externí odkaz:
http://arxiv.org/abs/2112.10500
Publikováno v:
CPT: Pharmacometrics and Systems Pharmacology, 2021
Optimal use and distribution of Covid-19 vaccines involves adjustments of dosing. Due to the rapidly-evolving pandemic, such adjustments often need to be introduced before full efficacy data are available. As demonstrated in other areas of drug devel
Externí odkaz:
http://arxiv.org/abs/2102.07610
Publikováno v:
In Journal of Pharmaceutical Sciences January 2024 113(1):22-32
Publikováno v:
Methods in Enzymology (Chapter Sixteen), 2021
Pore forming toxins (PFTs) are virulent proteins released by several species, including many strains of bacteria, to attack and kill host cells. In this article, we focus on the utility of molecular dynamics (MD) simulations and the molecular insight
Externí odkaz:
http://arxiv.org/abs/2010.13854
Publikováno v:
BioEssays, 2021
The affinity of antibodies (Abs) produced in vivo for their target antigens (Ags) is typically well below the maximum affinity possible. Nearly 25 years ago, Foote and Eisen explained how an 'affinity ceiling' could arise from constraints associated
Externí odkaz:
http://arxiv.org/abs/2002.02642
Autor:
Jayachandran, Priya1 (AUTHOR), Desikan, Rajat2 (AUTHOR), Krishnaswami, Sriram3 (AUTHOR) sriram.krishnaswami@pfizer.com, Hennig, Stefanie4,5 (AUTHOR)
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. Nov2023, Vol. 12 Issue 11, p1569-1572. 4p.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2020 Mar 01. 117(10), 5107-5108.
Externí odkaz:
https://www.jstor.org/stable/26929216
Autor:
Desikan, Rajat1 (AUTHOR) priya.jayachandran@pfizer.com, Jayachandran, Priya2 (AUTHOR)
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. Jan2023, Vol. 12 Issue 1, p5-7. 3p.
Autor:
Padmanabhan, Pranesh1 (AUTHOR), Desikan, Rajat2 (AUTHOR), Dixit, Narendra M.2,3 (AUTHOR) narendra@iisc.ac.in
Publikováno v:
PLoS Computational Biology. 12/8/2020, Vol. 16 Issue 12, p1-28. 28p. 1 Chart, 6 Graphs.
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