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Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.

Autor: Pishesha N; Whitehead Institute for Biomedical Research, Cambridge, MA 02142.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142.; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115., Bilate AM; Whitehead Institute for Biomedical Research, Cambridge, MA 02142., Wibowo MC; Whitehead Institute for Biomedical Research, Cambridge, MA 02142.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142., Huang NJ; Whitehead Institute for Biomedical Research, Cambridge, MA 02142., Li Z; Whitehead Institute for Biomedical Research, Cambridge, MA 02142.; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115., Deshycka R; Whitehead Institute for Biomedical Research, Cambridge, MA 02142.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142., Bousbaine D; Whitehead Institute for Biomedical Research, Cambridge, MA 02142.; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142., Li H; Whitehead Institute for Biomedical Research, Cambridge, MA 02142., Patterson HC; Whitehead Institute for Biomedical Research, Cambridge, MA 02142., Dougan SK; Whitehead Institute for Biomedical Research, Cambridge, MA 02142., Maruyama T; Whitehead Institute for Biomedical Research, Cambridge, MA 02142., Lodish HF; Whitehead Institute for Biomedical Research, Cambridge, MA 02142; lodish@wi.mit.edu hidde.ploegh@childrens.harvard.edu.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142., Ploegh HL; Whitehead Institute for Biomedical Research, Cambridge, MA 02142; lodish@wi.mit.edu hidde.ploegh@childrens.harvard.edu.; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Mar 21; Vol. 114 (12), pp. 3157-3162. Date of Electronic Publication: 2017 Mar 07.